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Repository of published systemic AAV experiments

rtyjteu
Updated November 14th 2024
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Capsid Result Species Target Promoter Cargo Dose Injection Incubation Doi Addgene Genome

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

104061

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

104061

PHP.S

NEG

Mouse, C57BL/6J

CNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

104061

PHP.S

POS

Mouse, C57BL/6J

PNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

104061

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

99129

PHP.eB

POS

Mouse, C57BL/6J

CNS, oligodendrocytes

MBP

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

99135

PHP.eB

POS

Mouse, C57BL/6J

CNS, serotonergic neurons

Ple67

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

49138

PHP.eB

POS

Mouse, C57BL/6J

CNS, catecholaminergic neurons

mTH

FP

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/nn.4593

99128

PHP.eB

POS

Mouse, C57BL/6J

CNS, purkinje neurons

Ple155

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/nn.4593

49140

PHP.eB

POS

Mouse, C57BL/6J

CNS, gabaergic interneurons

mDLX

FP

3E11 vg/animal

RO

8 weeks

https://doi.org/10.1038/nn.4593

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nbt.3440

37825

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/nbt.3440

37825

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

2E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nbt.3440

37825

PHP.B

POS

Mouse, GAD2-Cre

CNS, excitatory neurons

CaMKIIa

Sensor jRCaMP1b

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.neuron.2017.04.017

PHP.B

POS

Mouse, GAD2-Cre

CNS, GAD+ neurons

EF1a DIO

Sensor GCaMP6f

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.neuron.2017.04.017

PHP.B

POS

Mouse, SST-Cre

CNS, SST+ neurons

CAG DIO

Sensor GCaMP6f

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.neuron.2017.04.017

PHP.B

POS

Mouse, PV-Cre

CNS, PV+ neurons

CAG DIO

Sensor GCaMP6f

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.neuron.2017.04.017

PHP.B

POS

Mouse, Tac2-Cre

CNS, Tac2+ neurons

hSyn1 DIO

Rescue P2A FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.cell.2018.03.037

PHP.B

POS

Mouse, Tac2-Cre

CNS, Tac2+ neurons

hSyn1 DIO

Rescue P2A FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.cell.2018.03.037

PHP.B

POS

Mouse, Tac2-Cre

CNS, Tac2+ neurons

hSyn1 DIO

Chemogenetic hM3D(Gq)

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.cell.2018.03.037

44361

PHP.B

POS

Mouse, Tac2-Cre

CNS, Tac2+ neurons

hSyn1 DIO

FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.cell.2018.03.037

50459

PHP.B

POS

Mouse, Trim9 -/-

CNS, all

CAG

Rescue

1.5E12 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.celrep.2018.12.055

PHP.B

POS

Mouse, Trim9 -/-

CNS, all

CAG

FP

1.5E12 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.celrep.2018.12.055

PHP.S

POS

Mouse, Chat-Cre

PNS, cardiac ganglia, cholinergic neurons

CAG DIO

FP

3E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-019-09770-1

104058, 104059

PHP.S

POS

Mouse, Chat-Cre

PNS, cardiac ganglia, cholinergic neurons

CAG DIO

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-019-09770-1

127090

PHP.S

POS

Mouse, Chat-Cre

PNS, cardiac ganglia, cholinergic neurons

CAG DIO

Opsin, ChR2(H134R)-FP

1E12 vg/animal

RO

5 weeks

https://doi.org/10.1038/s41467-019-09770-1

PHP.eB

POS

Mouse, Nf1+/-

CNS, catecholaminergic neurons

rTh

FP

1E11 vg/animal

RO

<3 weeks

https://doi.org/10.7554/eLife.48983

133268, 99131, 99114, 99113

PHP.eB

NEG

Mouse, C57BL/6J

CNS, cortical neurons

hSyn1

Opsin, ChR2(H134R)-FP

5E11 vg/animal

RO

https://doi.org/10.1038/s41592-019-0583-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortical neurons

hSyn1

Opsin, ChRger2

5E11 vg/animal

RO

https://doi.org/10.1038/s41592-019-0583-8

127237

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortical neurons

hSyn1

Opsin, CoChR

1E11 vg/animal

RO

https://doi.org/10.1038/s41592-019-0583-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortical neurons

hSyn1

Opsin, ChRger2

1E11 vg/animal

RO

https://doi.org/10.1038/s41592-019-0583-8

127237

PHP.eB

POS

Mouse, C57BL/6J

CNS, excitatory neurons

CaMKIIa

Opsin, CoChR

1E11 vg/animal

RO

https://doi.org/10.1038/s41592-019-0583-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, excitatory neurons

CaMKIIa

Opsin, ChRger2

1E11 vg/animal

RO

https://doi.org/10.1038/s41592-019-0583-8

127238

PHP.eB

NEG

Mouse, Dat-Cre

CNS, dopaminergic neurons

CAG DIO

Opsin, ChR2(H134R)-FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-019-0583-8

PHP.eB

POS

Mouse, Dat-Cre

CNS, dopaminergic neurons

CAG DIO

Opsin, ChRger2

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-019-0583-8

127239

PHP.eB

NEG

Mouse, C57BL/6J

CNS, excitatory neurons

CaMKIIa

Opsin, ChR2(H134R)-FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-019-0583-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, excitatory neurons

CaMKIIa

Opsin, ChRger2

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-019-0583-8

127238

PHP.S

POS

Mouse, C57BL/6J aged

PNS, myenteric neurons

hSyn1-tTA TRE

Rescue

3.5E11 vg/animal

RO

2 weeks, 10 weeks

https://doi.org/10.1038/s41593-020-0589-7

99120

PHP.S

POS

Mouse, C57BL/6J aged

PNS, myenteric neurons

hSyn1-tTA TRE

Sensor, jRGECO1a

3.5E11 vg/animal

RO

2 weeks, 10 weeks

https://doi.org/10.1038/s41593-020-0589-7

99120

PHP.S

POS

Mouse, C57BL/6J aged

PNS, myenteric neurons

hSyn1-tTA TRE

Opsin, ChR2(H134R)-FP

1E11 vg/animal

RO

2 weeks, 10 weeks

https://doi.org/10.1038/s41593-020-0589-7

PHP.S

POS

Mouse, ASO aged

PNS, myenteric neurons

hSyn1-tTA TRE

Rescue

3.5E11 vg/animal

RO

2 weeks, 10 weeks

https://doi.org/10.1038/s41593-020-0589-7

PHP.S

POS

Mouse, ASO aged

PNS, myenteric neurons

hSyn1-tTA TRE

Sensor, jRGECO1a

3.5E11 vg/animal

RO

2 weeks, 10 weeks

https://doi.org/10.1038/s41593-020-0589-7

PHP.S

POS

Mouse, ASO aged

PNS, myenteric neurons

hSyn1-tTA TRE

Opsin, ChR2(H134R)-FP

1E11 vg/animal

RO

2 weeks, 10 weeks

https://doi.org/10.1038/s41593-020-0589-7

PHP.eB

POS

Mouse, FVB/B6

CNS, neurons

hSyn1

shRNA FP

RO

5 weeks

https://doi.org/10.1038/s41586-020-2156-5

PHP.V1

POS

Mouse, C57BL/6J

CNS, endothelial astrocytes

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

99134

PHP.V1

POS

Mouse, Tek-Cre

CNS, endothelial

CAG DIO

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-020-0799-7

104052

PHP.V1

POS

Mouse, Ai14

CNS, endothelial

Ple261

iCre

3E11 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-020-0799-7

49113

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.C1

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.N

POS

Mouse, C57BL/6J

CNS, neurons

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.N

POS

Mouse, C57BL/6J

CNS, neurons

CAG

FP

2E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.V1

NEG

Mouse, BALB/cJ

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.N

NEG

Mouse, BALB/cJ

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.B

NEG

Mouse, BALB/cJ

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.V1

POS

Mouse, FVB

CNS, endothelial astrocytes

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.N

POS

Mouse, FVB

CNS, neuron

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.C2

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.C3

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.C1

POS

Mouse, BALB/cJ

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.C2

POS

Mouse, BALB/cJ

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.C3

POS

Mouse, BALB/cJ

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.V2

POS

Mouse, C57BL/6J

CNS, endothelial astrocytes

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.V2

POS

Mouse, Tek-Cre

CNS, endothelial

CAG DIO

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-020-0799-7

104052

PHP.V2

POS

Mouse, GFAP-Cre

CNS, astrocytes

CAG DIO

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-020-0799-7

104052

PHP.V1

POS

Mouse, C57BL/6J

CNS, astrocytes

GfABC1D

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-020-0799-7

104053

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GfABC1D

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-020-0799-7

104053

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1.5E10 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41467-020-15818-4

37825

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

FP

1E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.celrep.2021.108754

163509

CAP-B10

POS

Mouse, C57BL/6J

CNS, neurons

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-021-00969-4

104061

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons, astrocyte bias, oligodendrocytes

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-021-00969-4

104061

PHP.eB

NHP, marmoset

CNS, all

CAG

HA-FXN

7E13 vg/kg

femoral vein, cephalic vein, saphenous vein

32 - 42 days

https://doi.org/10.1038/s41593-021-00969-4

CAP-B10

POS

NHP, marmoset

CNS, neuron bias, cortical, sub-cortex, cerebellum, spinal cord, dorsal root ganglia (DRG)

CAG

HA-FXN

7E13 vg/kg

femoral vein, cephalic vein, saphenous vein

32 - 42 days

https://doi.org/10.1038/s41593-021-00969-4

CAP-B22

POS

NHP, marmoset

CNS, cortex, astrocyte bias

CAG

HA-FXN

7E13 vg/kg

femoral vein, cephalic vein, saphenous vein

32 - 42 days

https://doi.org/10.1038/s41593-021-00969-4

PHP.eB

POS

Mouse, C57BL/6J

CNS, retinal neurons, photoreceptors

CAG

FP

1E11 vg/animal

RO

5 weeks

https://doi.org/10.1007/978-3-030-27378-1_18

59462

PHP.eB

POS

Mouse, C57BL/6J

CNS, retinal neurons, photoreceptors

CAG

FP

1E10 vg/animal

Subretinal

5 weeks

https://doi.org/10.1007/978-3-030-27378-1_18

59462

PHP.eB

NEG

Mouse, C57BL/6J

CNS, retinal neurons, photoreceptors

CAG

FP

1E10 vg/animal

Intravitreal

5 weeks

https://doi.org/10.1007/978-3-030-27378-1_18

59462

PHP.eB

POS

Rat, Sprague-Dawley

CNS, all

CAG

FP

1.2E13 vg/kg

Tail vein

4 weeks

https://doi.org/10.1038/s41434-018-0028-5

PHP.eB

POS

Rat, Sprague-Dawley

CNS, all

CAG

FP

3.6E13 vg/kg

Tail vein

4 weeks

https://doi.org/10.1038/s41434-018-0028-5

PHP.eB

POS

Rat, Sprague-Dawley

CNS, all

CAG

FP

1.2E14 vg/kg

Tail vein

4 weeks

https://doi.org/10.1038/s41434-018-0028-5

PHP.eB

POS

Mouse, C57BL/6J

CNS, excitatory neurons

CaMKIIa

FP

IV

3 weeks

https://doi.org/10.1038/s41596-019-0148-4

PHP.eB

POS

Mouse, C57BL/6J

CNS, inhibitory interneurons

mDLX

FP

IV

3 weeks

https://doi.org/10.1038/s41596-019-0148-4

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes, glutamatergic neurons, GABAergic neurons

CAG-NLS

FP

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes, neurons

CAG-NLS

FP

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

CAP-B10

POS

Mouse, C57BL/6J

CNS, glutamatergic neurons bias, GABAergic neurons, astrocytes

CAG-NLS

FP

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

CAP-B10

POS

Mouse, C57BL/6J

CNS, neurons bias, astrocytes

CAG-NLS

FP

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.V1

POS

Mouse, C57BL/6J

CNS, endothelial vascular cells bias, Myoc+ astrocytes

CAG-NLS

FP

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes (neuronal tropism not analyzed in this assay)

CAG-NLS

FP

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.V1

POS

Mouse, C57BL/6J

CNS, endothelial vascular cells bias, Myoc+ astrocytes

CAG-NLS

FP, RNA barcode

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes (neuronal tropism not analyzed in this assay)

CAG-NLS

FP, RNA barcode

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.eB

POS

Mouse, C57BL/6J

CNS, endothelial vascular cells bias, Myoc- astrocytes

CAG-NLS

FP

1.5E11vg/animal

RO

3 days

https://doi.org/10.3389/fimmu.2021.730825

PHP.eB

POS

Mouse, C57BL/6J

CNS, Myoc- astrocytes bias, glutamatergic neurns, GABAergic neurons, endothelial vascular cells

CAG-NLS

FP

1.5E11vg/animal

RO

25 days

https://doi.org/10.3389/fimmu.2021.730825

PHP.eB

POS

Mouse, C57BL/6J

CNS, Myoc- astrocytes

UBC

FP, RNA barcode

1.5E11 vg/variant (1.05E12/animal)

RO

3 weeks

https://doi.org/10.3389/fimmu.2021.730825

CAP-B10

POS

Mouse, C57BL/6J

CNS, glutamatergic neurons

UBC

FP, RNA barcode

1.5E11 vg/variant (1.05E12/animal)

RO

3 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.V1

POS

Mouse, C57BL/6J

CNS, endothelial vascular cells

UBC

FP, RNA barcode

1.5E11 vg/variant (1.05E12/animal)

RO

3 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.B

POS

Mouse, C57BL/6J

CNS, GABAergic neurons

UBC

FP, RNA barcode

1.5E11 vg/variant (1.05E12/animal)

RO

3 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.C1

NEG

Mouse, C57BL/6J

CNS, all

UBC

FP, RNA barcode

1.5E11 vg/variant (1.05E12/animal)

RO

3 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.C2

POS

Mouse, C57BL/6J

CNS, Myoc- astrocytes, endothelial vascular cells, and vascular LMCs

UBC

FP, RNA barcode

1.5E11 vg/variant (1.05E12/animal)

RO

3 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.B

POS

Mouse, Npc1m1N/m1N

CNS, hippocampus, striatum, cerebelllar molecular cell layer, and vestibular nucleus

EF1a(s)

FP

1.21E12 vg/animal

RO

5.5 weeks

10.26508/lsa.202101040

PHP.B

POS

Mouse, Npc1+/+

CNS, hippocampus, striatum, cerebelllar molecular cell layer, and vestibular nucleus

EF1a(s)

FP

1.21E12 vg/animal

RO

5.5 weeks

10.26508/lsa.202101040

PHP.B

POS

Mouse, Npc1m1N/m1N

CNS, cerebrum and cerebellum

EF1a(s)

Rescue

1.43E12 vg/animal

RO

5.5 weeks

10.26508/lsa.202101040

PHP.eB

POS

Mouse, 5xFAD

CNS, all

hSyn1

CRISPR, SaCas9, sgRNA

1E13 vg/animal

RO

3 months

10.1038/s41551-021-00759-0

PHP.eB

POS

Mouse, 5xFAD

CNS, hippocampus, cortex, medulla, and brain stem

hSyn1

CRISPR, SaCas9, sgRNA

1E13 vg/animal

RO

3 months

10.1038/s41551-021-00759-0

PHP.eB

POS

Mouse, Aldh1l1-Cre/ERT2

CNS, astrocytes, kidney, liver

CAG-FLEx

FP, Rescue, iBARK-mCherry

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.neuron.2021.05.023

117693

PHP.eB

POS

Mouse, Aldh1l1-Cre/ERT2

CNS, astrocytes, kidney, liver

CAG-FLEx

FP, Rescue, iBARK D110A-mCherry

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.neuron.2021.05.023

117694

PHP.B

POS

Mouse, C57BL/6J

CNS, cortial, striatal, and hippocampal neurons

CAG

FP

1E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1093/braincomms/fcab105

PHP.B

NEG

Mouse, CBA/Ca

CNS, all

CAG

FP

1E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1093/braincomms/fcab105

PHP.eB

POS

Mouse, C57BL/6J

Liver and CNS, cortex, striatum, hippocampus, cerebellum, brainstem

CAG

FP

1E11 vg/animal

Tail vein

2 hours

https://doi.org/10.1093/braincomms/fcab105

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortex, pyramidal tract (PT) neurons in L5 layer

mscRE4-pBCmin

FP

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortex, pyramidal tract (PT) neurons in L5 layer bias

mscRE4-pBCmin

FP

1-4E10 vg/site

Intracranial (VISp)

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortex, intratelencephalic (IT) neurons in L5 layer bias

mscRE16-pBCmin

FP

1-4E9 vg/site

Intracranial (VISp)

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortex, pyramidal tract (PT) neurons in L5 layer

3x Core mscRE4-pCMVmin

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai65F

CNS, cortex, pyramidal tract (PT) neurons in L5, dense labeling

mscRE4-pBCmin

Recombinase, FlpO

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai14

CNS, cortex nonspecific

mscRE4-pBCmin

Recombinase, dgCre

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai14

CNS, cortex exitatory neurons in L5 and L6

mscRE4-pBCmin

Recombinase, iCre

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai63

CNS, cortex, neurons in L5, sparse labeling

mscRE4-pBCmin

Inducer, tTA2

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai65F

CNS, cortex, pyramidal tract (PT) neurons in L5, dense labeling

mscRE4-pBCmin

Recombinase, FlpO

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai65F

CNS, cortex, corticothamic (CT) neurons in L6 bias, sparse labeling

mscRE10-pBCmin

Recombinase, FlpO

1E10 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai65F

CNS, cortex, CT, IT, and PT neurons in L5 and L6

mscRE13-pBCmin

Recombinase, FlpO

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai65F

CNS, cortex, intratelencephalic (IT) neurons in L5 bias

mscRE16-pBCmin

Recombinase, FlpO

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai65F/wt; Ai140/wt (double reporter)

CNS, cortex, intratelencephalic (IT) neurons in L5

mscRE16-pBCmin

Recombinase, FlpO

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai65F/wt; Ai140/wt (double reporter)

CNS, cortex, pyramidal tract (PT) neurons in L5

mscRE4-pBCmin

Recombinase, iCre

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, neurons

pSyn

Recombinase, Cre

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, neurons

pSyn

Recombinase, FlpO

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, neurons

pSyn

Recombinase, oNigri

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, pan-neuronal

pSyn

Recombinase, Cre

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, pan-neuronal

pSyn

Recombinase, FlpO

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, pan-neuronal

pSyn

Recombinase, oNigri

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, distinct neuronal subclasses

hl56i

Recombinase, iCre-4X2C

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, distinct neuronal subclasses

mscRE4

Recombinase, FlpO

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, distinct neuronal subclasses

mscRE16

Recombinase, oNigri

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Human, neocortical slice culture

CNS, cortex, sparse labeling L2-L6

mscRE4

FP, Recombinase, FlpO

direct application to slice

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.S

POS

Mouse, NAMPT:MPZ-Cre

PNS, DRG neurons

hSyn1

FP

Intrathecal

2 weeks

https://doi.org/10.1523/JNEUROSCI.3304-17.2018

50465

PHP.S

POS

Mouse, C57BL/6J

CNS, cerebellum vestibular ganglion neurons

CAG

FP

3.4E11 vg/animal

posterior semicircular canal

2 weeks

https://doi.org/10.7554/eLife.44964

59462

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1-H2B

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163509

PHP.eB

POS

Mouse, C57BL/6J

CNS, telencephalic interneurons

hDLXI56i-minBG

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163493

PHP.eB

POS

Mouse, C57BL/6J

CNS, SLC17a7+ neurons, excitatory IT neurons in L56 bias

eHGT_078h-minBG

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163495

PHP.eB

POS

Mouse, C57BL/6J

CNS, RORB+ neurons in L4, excitatory IT neurons in L56

eHGT_058h-minBG

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163494

PHP.eB

POS

Mouse, C57BL/6J

CNS, LAMP5+ inhibitory neurons

eHGT_019h-minBG

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163496

PHP.eB

POS

Mouse, C57BL/6J

CNS, SST+ neuronal bias, VIP+ neurons

eHGT_017h-minBG

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163497

PHP.eB

POS

Mouse, C57BL/6J

CNS, PVALB+ neurons

eHGT_128h-minRho

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163498

PHP.eB

POS

Mouse, C57BL/6J

CNS, PVALB+ neurons

eHGT_079h-minRho

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163501

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortex, PVALB+ neurons, midbrain structures, deep cerebellar nuclei, and main olfactory bulb

eHGT_082h-minRho

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163502

PHP.eB

POS

Mouse, C57BL/6J

CNS, PVALB+ neurons

eHGT_140h-minRho

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163503

PHP.eB

POS

Mouse, C57BL/6J

CNS, PVALB+ neurons

eHGT_359h-minRho

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163504

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortex, PVALB+ neurons bias, SST+ neurons, cerebellar Purkinje cells, mid/hindbrain nuclei, hippocampus, and main olfactory bulb neurons

eHGT_023h-minBG

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163499

PHP.eB

POS

Mouse, C57BL/6J

CNS, PVALB+ neurons bias, SST+ neurons

eHGT_064h-minBG

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163500

PHP.eB

POS

NHP, Macaca mulatta

CNS, PVALB+ neurons

eHGT_079h_minRho

FP

1-2E11 vg/site

Intracranial (occipital)

51-113 days

10.1016/j.celrep.2021.108754

163501

PHP.eB

POS

NHP, Macaca nemestrina

CNS, PVALB+ neurons

eHGT_082h-minRho

FP

1-2E11 vg/site

Intracranial (occipital)

51-113 days

10.1016/j.celrep.2021.108754

163502

PHP.eB

POS

NHP, Macaca mulatta

CNS, PVALB+ neurons

eHGT_128h-minRho

FP

1-2E11 vg/site

Intracranial (occipital)

51-113 days

10.1016/j.celrep.2021.108754

163498

PHP.eB

POS

NHP, Macaca nemestrina

CNS, PVALB+ neurons

eHGT_359h-minRho

FP

1-2E11 vg/site

Intracranial (occipital)

51-113 days

10.1016/j.celrep.2021.108754

163504

PHP.eB

POS

NHP, Macaca mulatta

CNS, PVALB+ neurons

eHGT_140h-minRho

FP

1-2E11 vg/site

Intracranial (occipital)

51-113 days

10.1016/j.celrep.2021.108754

163503

PHP.eB

POS

NHP, Macaca mulatta

CNS, PVALB+ neurons

eHGT_140h-minRho

FP

1-2E11 vg/site

Intracranial (temporal)

51-113 days

10.1016/j.celrep.2021.108754

163503

PHP.eB

POS

NHP, Macaca nemestrina

CNS, PVALB+ neurons

eHGT_140h-minRho

FP

1-2E11 vg/site

Intracranial (somatosensory)

51-113 days

10.1016/j.celrep.2021.108754

163503

PHP.eB

POS

NHP, Macaca nemestrina

CNS, PVALB+ neurons

eHGT_140h-minRho

FP

1-2E11 vg/site

Intracranial (motor)

51-113 days

10.1016/j.celrep.2021.108754

163503

PHP.eB

POS

NHP, Macaca nemestrina, temporal cortex brain slice culture

CNS, L2–L6 excitatory neurons

eHGT_078m-minBG

FP

2-3E10 vg/slice

direct application to slice

1-2 weeks

10.1016/j.celrep.2021.108754

163508

PHP.eB

POS

NHP, Macaca nemestrina, temporal cortex brain slice culture

CNS, L3–L5 pyramidal neurons

eHGT_058h-minBG

FP

2-3E10 vg/slice

direct application to slice

1-2 weeks

10.1016/j.celrep.2021.108754

163494

PHP.eB

POS

NHP, Macaca nemestrina, temporal cortex brain slice culture

CNS, GAD1+ GABAergic neurons

DLX2.0_minBG

FP

2-3E10 vg/slice

direct application to slice

1-2 weeks

10.1016/j.celrep.2021.108754

163505

PHP.eB

POS

NHP, Macaca nemestrina, temporal cortex brain slice culture

CNS, GAD1+ and PVALB+ low specificity

eHGT_079h_minRho

FP

2-3E10 vg/slice

direct application to slice

1-2 weeks

10.1016/j.celrep.2021.108754

163501

PHP.eB

POS

NHP, Macaca nemestrina, temporal cortex brain slice culture

CNS, GAD1+ and PVALB+ low specificity

eHGT_082h-minRho

FP

2-3E10 vg/slice

direct application to slice

1-2 weeks

10.1016/j.celrep.2021.108754

163502

PHP.eB

POS

NHP, Macaca nemestrina, temporal cortex brain slice culture

CNS, GAD1+ and PVALB+ low specificity

eHGT_128h-minRho

FP

2-3E10 vg/slice

direct application to slice

1-2 weeks

10.1016/j.celrep.2021.108754

163498

PHP.eB

POS

NHP, Macaca nemestrina, temporal cortex brainslice culture

CNS, GAD1+ and PVALB+ low specificity

eHGT_140h-minRho

FP

2-3E10 vg/slice

direct application to slice

1-2 weeks

10.1016/j.celrep.2021.108754

163503

PHP.eB

POS

Human, temportal cortex brain slice culture

CNS, GAD1+ inhibitory neurons

hDLXI56i-minBG

FP

2-3E10 vg/slice

direct application to slice

8, 13, 28, and 69 days

10.1016/j.celrep.2021.108754

163493

PHP.eB

POS

Human, temportal cortex brain slice culture

CNS, GAD1+ inhibitory neurons

DLX2.0_minBG

FP

2-3E10 vg/slice

direct application to slice

7, 7, 14, and 34 days

10.1016/j.celrep.2021.108754

163505

PHP.eB

POS

Mouse, Ai14

CNS, cortex

EF1a

Recombinase, Cre

4-8E10 vg/animal

ICV

2 weeks

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Ai14

CNS, cortex

EF1a

Recombinase, Cre

--

RO

2 weeks

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Ai66R

CNS, cortex

EF1a

Recombinase, CDreV

4-8E10 vg/animal

ICV

2 weeks

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Ai66R

CNS, cortex

Syn

Recombinase, NDreV

4-8E10 vg/animal

ICV

2 weeks

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Ai75

CNS, cortex

EF1a

Recombinase, iCreV

4-8E10 vg/animal

ICV

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Ai65F

CNS, cortex

EF1a

Recombinase, iFlpV

4-8E10 vg/animal

ICV

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Rbp4-Cre

CNS, cortex

EF1a, FSF-FLEX

FP

1-2E10 vg/animal

Intracranial (cortex)

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Rbp4-Cre

CNS, cortex

EF1a

Recombinase, iFlpV

1-2E10 vg/animal

Intracranial (cortex)

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Sst-IRES-FlpO x Ai65

CNS, cortex, somatostatin-positive inhibitory interneurons

EF1a

Recombinase, iCreV

--

RO

https://doi.org/10.1038/s41592-020-0774-3

Cu64labeled-PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1.5E10 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41467-020-15818-4

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1.5E10 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41467-020-15818-4

37825

Cu64labeled-PHP.eB

POS

Mouse, C57BL/6J

CNS and spleen

CAG

FP

1.5E10 vg/animal

Tail vein

4 hours

https://doi.org/10.1038/s41467-020-15818-4

Cu64labeled-PHP.eB

POS

Mouse, C57BL/6J

CNS bias and spleen

CAG

FP

1.5E10 vg/animal

Tail vein

21 hours

https://doi.org/10.1038/s41467-020-15818-4

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

FP

3E11 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

3E11 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41596-018-0097-3

104053

PHP.eB

POS

Mouse, C57BL/6J

CNS, oligodendrocytes

MBP

FP

3E11 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41596-018-0097-3

104054

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

CAG miR-204TS

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

CAG miR-708TS

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.S

POS

Mouse, TH-IRES-Cre

PNS, paravertebral ganglia

CAG DIO

FP

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41596-018-0097-3

104058

PHP.S

POS

Mouse, TH-IRES-Cre

PNS, paravertebral ganglia

hSyn1

FP

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41596-018-0097-3

99135

PHP.S

POS

Mouse, TRPV1-IRES-Cre

PNS, nodose ganglion

CAG DIO

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

104052

PHP.S

POS

Mouse, TRPV1-IRES-Cre

PNS, DRG

CAG DIO

FP

3E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41596-018-0097-3

104058, 104059

PHP.S

POS

Mouse, C57BL/6J

PNS, duodenum, myenteric plexus, submucosal plexus

mTH

FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.S

POS

Mouse, C57BL/6J

PNS, duodenum, myenteric plexus, submucosal plexus

hSyn

FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

104060

PHP.S

POS

Mouse, C57BL/6J

Heart

CAG

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41596-018-0097-3

104061

PHP.S

POS

Mouse, C57BL/6J

Heart, cardiac muscle

CAG

FP

1E12 vg/animal

RO

11 days

https://doi.org/10.1038/s41596-018-0097-3

99134, 99123, 99122

PHP.S

POS

Mouse, TRPV1-IRES-Cre

PNS, cardiac nerves

CAG DIO

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

99133, 104058, 104059

PHP.S

POS

Mouse, ChAT-IRES-Cre

PNS, cardiac ganglion

Ef1a DIO

ChR2, FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

20298

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

99134

PHP.B

POS

Mouse, FVB/NCrl

CNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

99134

PHP.B

POS

Mouse, 129S1/SvlmJ

CNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

99134

PHP.B

NEG

Mouse, BALB/cJ

CNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

99134

PHP.eB

POS

Mouse, 129T2/SvEmsJ

CNS, all

CAG

FP

3E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.eB

POS

Rat, Fischer

CNS, all

CAG

FP

3E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.eB

POS

Rat, Long-Evans

CNS, neurons, liver detarget

CMV-hSyn1 miR122TS

Sensor, GCaMP6f

1E13 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.B

POS

Mouse, FVB/NCrl

CNS, neurons

CaMKIIa

Sensor, CaMPARI

3E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

Sensor, SPOTlight

3E11 vg/animal

RO

2 weeks

https://doi.org/10.1126/science.abe1931

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1126/science.abe1931

PHP.S

POS

Mouse, Mrgpra3Cre; NmbrCre; RosaTdtf/+

PNS, spinal neurons

CAG DIO

Opsin, ChR2, FP

7.5E10 vg/animal

Intrathecal

3 weeks

https://doi.org/10.1016/j.neuron.2021.12.007

PHP.B

POS

Rat, Sprague-Dawley, neonate

CNS, all

CBA

FP

1.9E12 vg/animal

Facial vein

4 weeks

https://doi.org/10.3389/fnmol.2016.00116

PHP.B

POS

Rat, Sprague-Dawley

CNS, neurons

Syn

FP

3.8E13 vg/kg

RO or Tail vein

4 weeks

https://doi.org/10.3389/fnmol.2016.00116

PHP.B

POS

Rat, Sprague-Dawley, neonate

CNS, all

CBA

Disease model

1.6E12 vg/animal

Facial vein

<10 days

https://doi.org/10.3389/fnmol.2016.00116

PHP.B

POS

Rat, Sprague-Dawley

CNS, all

CBA

Disease model

3E13 vg/kg

RO or Tail vein

2 weeks

https://doi.org/10.3389/fnmol.2016.00116

PHP.B

POS

Mouse, FRMD7tm1a(KOMP)Wtsi

CNS, all

EF1a

Sensor, GCaMP6s

1.7E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4566

PHP.B

POS

Mouse, BChE KO

CNS, all

Rescue

1E13 vg/animal

Tail vein

3 weeks

https://doi.org/10.3390/molecules22071145

PHP.B

POS

Mouse, C57BL/6J

CNS, purkinje neurons

L7-6

FP

3E12 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2017.07.006

PHP.B

POS

Mouse, AβPPswe/PS-1

CNS, hippocampus

IE4/5

Rescue

Intracranial (hippocampus)

2.5 weeks

https://doi.org/10.1093/brain/awx272

PHP.B

POS

Mouse, AβPPswe/PS-1

CNS, hippocampus

IE4/5

FP

Intracranial (hippocampus)

2.5 weeks

https://doi.org/10.1093/brain/awx272

PHP.B

POS

Mouse, C57BL/6J

CNS, all, DRG, Sympathetic ganglia

CBA

FP

2E12 vg/animal

Tail vein

3-5 weeks

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, neonate

CNS, all, Spinal cord

CBA

FP

1.5E11 vg/animal

Facial vein

3 weeks

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, Ai9

CNS, all

CBA

Recombinase, Cre

1E9 - 1E12 vg/animal

Tail vein

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, NeuroD6-Cre

CNS, neurons cortex hippocampus

CBA FLEX

FP

2E12 vg/animal

Tail vein

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, PV-Cre

CNS, gabaergic interneurons

CBA FLEX

FP

2E12 vg/animal

Tail vein

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, Dat-Cre

CNS, dopaminergic neurons

CBA FLEX

FP

2E12 vg/animal

Tail vein

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, Olig2-Cre

CNS, oligodendrocytes

CBA FLEX

FP

2E12 vg/animal

Tail vein

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, PV-Cre

CNS, gabaergic interneurons

Syn FLEX

Chemogenetic DREADDM4, FP

2E12 vg/animal

Tail vein

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, Tsc1f/f

CNS, all

CBA

Recombinase, Cre

2E12 vg/animal

Tail vein

1 week

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, Tsc1f/f

CNS, all

CBA

Recombinase, Cre

1E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, A53T-SCNA

CNS, all

EF1a

Rescue, FP

2E12 vg/animal

Tail vein

3 - 5 months

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, C57BL/6J

CNS, all, reduced periphery

CBA

FP

2E12 vg/animal

Carotid artery

3 weeks

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, C57BL/6J

CNS, all

FP

5E13 vg/kg

https://doi.org/10.1016/j.ymthe.2018.01.018

PHP.B

NEG

Mouse, BALB/cJ

CNS, all

FP

5E13 vg/kg

https://doi.org/10.1016/j.ymthe.2018.01.018

PHP.B

NEG

NHP, rhesus macaque

CNS, all

FP

7.5E13 vg/kg

5 days

https://doi.org/10.1016/j.ymthe.2018.01.018

PHP.B

NEG

NHP, rhesus macaque

CNS, all

FP

2E13 vg/kg

3 weeks

https://doi.org/10.1016/j.ymthe.2018.01.018

PHP.B

POS

Mouse, C57BL/6J

CNS, all

Sensor, GCaMP6s

RO

https://doi.org/10.1038/nbt.4034

PHP.B

NEG

NHP, marmoset

CNS, all

CBh

FP

5E13 vg/kg

femoral vein

6 weeks

https://doi.org/10.1016/j.neulet.2017.11.049

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBh

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.neulet.2017.11.049

PHP.B

POS

Mouse, Rho+/P23H

Retina

CBA

FP

1E12 vg/animal

Intravitreal

2 weels

https://doi.org/10.1093/hmg/ddx438

PHP.B

POS

Mouse, Rho+/P23H

Retina

TetO

CRISPR, SpCas9-VQR

1E12 vg/animal

Intravitreal

2 weels

https://doi.org/10.1093/hmg/ddx438

PHP.B

POS

Mouse, Rho+/P23H

Retina

hRho

CRISPR, sgRNA, Inducer

1E12 vg/animal

Intravitreal

2 weels

https://doi.org/10.1093/hmg/ddx438

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBA self complimentary

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41434-018-0005-z

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBA self complimentary

FP

2.5E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41434-018-0005-z

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn self complimentary

FP

2E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41434-018-0005-z

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn self complimentary

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41434-018-0005-z

PHP.B

POS

Mouse, Gja10-Cre

Retina

Ef1a DIO

Rescue

3E14 vg/kg

RO

4-5 weeks

https://doi.org/10.1016/j.neuron.2018.06.001

PHP.B

POS

Mouse, Gja10Cre × PV-Flp × Flp-GFP-reporter

Retina

Ef1a DIO

Rescue

3E14 vg/kg

RO

4-5 weeks

https://doi.org/10.1016/j.neuron.2018.06.001

PHP.B

POS

Mouse, C57BL/6J

Spinal cord

hSyn

Rescue

1E12 vg/animal

Tail vein

8 weeks

https://doi.org/10.1016/j.cell.2018.06.005

PHP.B

POS

Mouse, C57BL/6J

Spinal cord

hSyn

FP

1E12 vg/animal

Tail vein

8 weeks

https://doi.org/10.1016/j.cell.2018.06.005

PHP.B

POS

Mouse, Chat-Cre

Spinal cord

hSyn FLEX

Rescue

1E12 vg/animal

Tail vein

8 weeks

https://doi.org/10.1016/j.cell.2018.06.005

PHP.B

POS

Mouse, Vglut2-Cre

Spinal cord

hSyn FLEX

Rescue

1E12 vg/animal

Tail vein

8 weeks

https://doi.org/10.1016/j.cell.2018.06.005

PHP.B

POS

Mouse, Vgat-Cre

Spinal cord

hSyn FLEX

Rescue

1E12 vg/animal

Tail vein

8 weeks

https://doi.org/10.1016/j.cell.2018.06.005

PHP.B

POS

Mouse

Cochlea neurons

hSyn

Opsin, Chronos

1-2E9 vg/animal

Cochlea

4-12 weeks

https://doi.org/10.15252/embj.201899649

PHP.B

POS

Mouse, neonate

Cochlea neurons

hSyn

Opsin, Chronos

1-2E9 vg/animal

Cochlea

4-12 weeks

https://doi.org/10.15252/embj.201899649

PHP.eB

POS

Mouse, GFAP-mCAT

CNS, astrocytes

GFAP

FP

5E10 vg/animal

RO

3 weeks

https://doi.org/10.1038/s42255-018-0031-6

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Sensor, GCaMP6s

6E11 vg/animal

Tail vein

4-8 weeks

https://doi.org/10.1117/1.NPh.6.2.025014

PHP.eB

POS

Mouse, fos-cre −/−

CNS, neurons

hSyn

Sensor, GCaMP6s

6E11 vg/animal

Tail vein

4-8 weeks

https://doi.org/10.1117/1.NPh.6.2.025014

PHP.eB

NEG

Mouse, C57BL/6J

Inner ear

CAG

FP

3.6E9 vg/animal

Round window membrane

https://doi.org/10.1038/s41467-019-11687-8

PHP.eB

POS

Mouse, C57BL/6J aged

CNS, oligodendrocytes

CMV

CRISPR, SpCas9

5E11 vg/animal

Tail vein

4 weeks

https://doi.org/10.1038/s41586-019-1484-9

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, oligodendrocytes

CMV

CRISPR, SpCas9

5E10 vg/animal

Tail vein

4 weeks

https://doi.org/10.1038/s41586-019-1484-9

PHP.eB

POS

Mouse, Sim1-Cre

CNS, neurons

hSyn FLEX

Recombinase, FLPo

RO

https://doi.org/10.1016/j.cell.2019.07.042

122503

PHP.eB

POS

Mouse, Sim1-Cre

CNS, neurons

CAG FRT

FP

RO

https://doi.org/10.1016/j.cell.2019.07.042

122504

PHP.eB

POS

Mouse, AKR/J

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

POS

Mouse, C57L/J

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

POS

Mouse, DBA/J

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

NEG

Mouse, BALB/cJ

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

POS

Mouse, FVB/NJ

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

POS

Mouse, LP/J

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

POS

Mouse, MOLF/EiJ

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

NEG

Mouse, CAST/EiJ

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

NEG

Mouse, CBA/J

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

NEG

Mouse, NOD/ShiLtJ

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

NEG

Mouse, NZB/B1NJ

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

NEG

Mouse, PWK/PhJ

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

POS

Mouse, C57BL/6J aged

CNS, all

CAG

FP

4E11 vg/animal

6-12 months

https://doi.org/10.1186/s13059-019-1866-1

PHP.eB

POS

Mouse, C57BL/6J aged

CNS, all

CAG

Rescue, FP

4E11 vg/animal

6-12 months

https://doi.org/10.1186/s13059-019-1866-1

PHP.eB

POS

Mouse, C57BL/6N or 6J

CNS, neurons

NSE

FP

6.4E11 vg/animal

RO

1 month

https://doi.org/10.1038/s41596-019-0240-9

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBh

Rescue, FP

1-3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.nbd.2018.10.014

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBA self complimentary

FP

1E12 vg/animal

Tail vein

3 weeks

10.3791/58960

PHP.B

POS

Mouse, GAAKO

CNS, all

CMV/CB

Rescue

5E12 vg/kg

RO

14 weeks

https://doi.org/10.1016/j.omtm.2019.01.006

PHP.B

POS

Mongolian gerbil

Inner ear neurons

hSyn

Opsin, ChR2 CatCH

1E10 vg/animal

cochlea spiral ganglion

4 weeks

https://doi.org/10.1038/s41467-019-09980-7

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

NEG

Mouse, BALB/cJ

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

NEG

Mouse, Ly6a-KO

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

POS

Mouse, 129S1/SvlmJ

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

POS

Mouse, DBA/2J

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

POS

Mouse, FVB/NJ

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

NEG

Mouse, C3H/HeJ

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

NEG

Mouse, CBA/J

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

NEG

Mouse, A/J

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1007/s12035-018-1366-4

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

rNSE

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1007/s12035-018-1366-4

PHP.B

NEG

Rat, Sprague-Dawley

CNS

FP

4-5E13 vg/kg

3 weeks

https://doi.org/10.1007/s12035-018-1366-4

PHP.B

NEG

Mouse

Inner ear

CMV

FP

1E7 vg/animal

Round window membrane

3 weeks

https://doi.org/10.1016/j.omtm.2019.01.002

PHP.B

POS

Mouse, C57BL/6J neonate

Inner ear

CBA

FP

5E10 vg/animal

Round window membrane

5 days

https://doi.org/10.1016/j.omtm.2018.11.003

PHP.B

POS

Mouse, CD1 neonate

Inner ear

CBA

FP

5E10 vg/animal

Round window membrane

5 days

https://doi.org/10.1016/j.omtm.2018.11.003

PHP.B

POS

Mouse, Crln1−/− neonate

Inner ear

CBA

Rescue

7.4E10 vg/animal

Round window membrane

4 weeks

https://doi.org/10.1016/j.omtm.2018.11.003

PHP.B

POS

Mouse, Crln1−/− neonate

Inner ear

CBA

Rescue

1.8E11 vg/animal

Round window membrane

4 weeks

https://doi.org/10.1016/j.omtm.2018.11.003

PHP.B

POS

Mouse, C57BL/6J

Retina

CBA

FP

2.1E9 vg/animal

subretinal

8 days

https://doi.org/10.1016/j.omtm.2018.11.003

PHP.B

NHP, cynologous monkey

Inner ear

CBA

FP

3E11 vg/animal

Round window membrane

7 weeks

https://doi.org/10.1016/j.omtm.2018.11.003

PHP.B

POS

Mouse, C57BL/6J

PNS, sciatic nerve

CMV

FP

2E11 vg/animal

Tail vein

5 weeks

https://doi.org/10.1016/j.neulet.2019.05.010

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

3E10 vg/animal

jugular vein

https://doi.org/10.1016/j.ymthe.2019.07.017

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

3E10 vg/animal

Carotid artery

https://doi.org/10.1016/j.ymthe.2019.07.017

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

3E10 vg/animal

lateral ventricle

https://doi.org/10.1016/j.ymthe.2019.07.017

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

3E10 vg/animal

intrathecal, cisterna magna

https://doi.org/10.1016/j.ymthe.2019.07.017

PHP.B

NEG

NHP, rhesus macaque juvenile

CNS, all

CAG

FP

1E12 vg/kg

Carotid artery

https://doi.org/10.1016/j.ymthe.2019.07.017

PHP.B

NEG

NHP, rhesus macaque juvenile

CNS, all

CAG

FP

1E12 vg/kg

intrathecal, cisterna magna

https://doi.org/10.1016/j.ymthe.2019.07.017

PHP.eB

POS

Mouse, C3H/He-C57BL/6 hybrid

CNS, all, Retina

CAG

FP

3.3E9 vg/animal

Tail vein

3 weeks

doi:10.7150/thno.42611

PHP.eB

POS

Mouse, Meg+/+, 129/svJ background

CNS, all

CAG

FP

5E10 vg/animal

Tail vein

3 weeks

https://doi.org/10.1093/braincomms/fcaa135

37825

PHP.eB

POS

Mouse, Meg+/-, 129/svJ background

CNS, all

CAG

FP

5E10 vg/animal

Tail vein

3 weeks

https://doi.org/10.1093/braincomms/fcaa135

37825

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

EF1a

Opsin, LINuS

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.bbrc.2019.11.023

PHP.eB

POS

Mouse, Fah−/−/Rag2−/−/Il2rg−/− (FRG)

CNS, all

CMV

FP

3.3E9 vg/animal

Tail vein

7 days

https://doi.org/10.1089/hum.2019.264

PHP.B

POS

Mouse, B6/C3H neonate

CNS, all

CAG

FP

1.5E8 vg/site

ICV

30 days

https://doi.org/10.1186/s13024-020-00361-z

PHP.eB

POS

Mouse, B6/C3H neonate

CNS, all

CAG

FP

3.6E8 vg/site

ICV

30 days

https://doi.org/10.1186/s13024-020-00361-z

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CBA-iMecp2

Rescue

1E11 vg/animal

Tail vein

up to 15 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CBA-iMecp2

Rescue

1E12 vg/animal

Tail vein

up to 15 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

NEG

Mouse, Mecp2-/y

CNS, all

CBA-iMecp2

Rescue

1E9 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2-/y

CNS, all

CBA-iMecp2

Rescue

1E10 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2-/y

CNS, all

CBA-iMecp2

Rescue

1E11 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2-/y

CNS, all

CBA-iMecp2

Rescue

1E12 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

NEG

Mouse, Mecp2-/y

CNS, all

CBA

FP

1E9 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2-/y

CNS, all

CBA

FP

1E10 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2-/y

CNS, all

CBA

FP

1E11 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2-/y

CNS, all

CBA

FP

1E12 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2+/-

CNS, all

CBA-iMecp2

Rescue

1E11 vg/animal

Tail vein

up to 15 months

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2+/-

CNS, all

CBA

FP

1E11 vg/animal

Tail vein

up to 15 months

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, C57BL/6J

CNS, spinal cord sciatic neurons

Syn

Rescue, FP

6E11 vg/animal

Tail vein

3 days or 4 weeks

https://doi.org/10.1172/JCI125771

PHP.eB

POS

Mouse, C57BL/6J

CNS, spinal cord sciatic neurons

Syn

FP

6E11 vg/animal

Tail vein

3 days or 4 weeks

https://doi.org/10.1172/JCI125771

PHP.eB

POS

Mouse, C57BL/6J

CNS, striatum astrocytes

GFAP

CRISPR, CasRx, sgRNA

1-3E10 vg/site

Intracranial (striatum)

1 week, 1 month, 3 months

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, C57BL/6J

CNS, striatum astrocytes

GFAP

CRISPR, CasRx

1-3E10 vg/site

Intracranial (striatum)

1 week, 1 month, 3 months

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, C57BL/6J

CNS, striatum astrocytes

GFAP

FP

1-3E10 vg/site

Intracranial (striatum)

1 week, 1 month, 3 months

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, C57BL/6J

Retina, astrocytes

GFAP

CRISPR, CasRx, sgRNA

1E10 vg/site

subretinal

2-3 weeks

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, C57BL/6J

Retina, astrocytes

GFAP

CRISPR, CasRx

1E10 vg/site

subretinal

2-3 weeks

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, C57BL/6J

Retina, astrocytes

GFAP

FP

1E10 vg/site

subretinal

2-3 weeks

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, Ai9

Retina, astrocytes

GFAP

CRISPR, CasRx, sgRNA

1E10 vg/site

subretinal

2-3 weeks, 1 month

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, Ai9

Retina, astrocytes

GFAP

CRISPR, CasRx

1E10 vg/site

subretinal

2-3 weeks, 1 month

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, Ai9

Retina, astrocytes

GFAP

FP

1E10 vg/site

subretinal

2-3 weeks, 1 month

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, Hdac1 cKO aged

CNS, neurons

shRNA, FP

Intracranial (hippocampus)

3 weeks

https://doi.org/10.1038/s41467-020-16361-y

PHP.eB

NEG

Mouse, C57BL/6J neonate

CNS, neurons

Syn

Sensor, GCaMP6s

8E10 vg/site

transverse sinus

5 days - 3 weeks

https://doi.org/10.7554/eLife.53639

100843

PHP.eB

POS

Mouse

CNS, neurons, retina

CAG FLEX

Inducer, tTA2

RO

3 weeks

DOI: 10.1126/science.aaz5887

PHP.eB

POS

Mouse, CaMKIIa-Cre

CNS, neurons

hSyn DIO

FP

1.3E11 vg/animal

RO

3 weeks

https://doi.org/10.3389/fncel.2020.00145

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons, spinal cord

LAP1

FP

4E11 vg/animal

RO

30 days, 190 days

https://doi.org/10.1016/j.omtm.2020.04.004

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons, spinal cord

LAP2

FP

4E11 vg/animal

RO

30 days, 190 days

https://doi.org/10.1016/j.omtm.2020.04.004

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons, spinal cord

LAP1_2

FP

4E11 vg/animal

RO

30 days, 190 days

https://doi.org/10.1016/j.omtm.2020.04.004

PHP.eB

POS

Mouse, C57BL/6J

CNS, all, spinal cord

EF1a

FP

4E11 vg/animal

RO

30 days, 190 days

https://doi.org/10.1016/j.omtm.2020.04.004

PHP.eB

POS

Mouse, floxed-dCas9-VPRVPR/+/Vgat-CreCre/+/Scn1aRX/+

CNS, parvalbumin gabaergic neurons

4x U6

CRISPRa, sgRNA

1.8E11 vg/animal

Tail vein

8 weeks

https://doi.org/10.1016/j.nbd.2020.104954

43860

PHP.eB

POS

Mouse, Klb-CRE

CNS, hypothalamus

CAG FLEX

FP

RO

4 weeks

https://doi.org/10.1016/j.cmet.2020.06.008

28306

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons

E2

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons

Dlx

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons

E2

FP

1E12 vg/animal

RO

1 week

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons

E2

Chemogenetic PSAM4-5HT3-LC

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons, upper cortex layers

E11

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons, upper cortex layers

E14

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons cortex

E22

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons global

E29

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Rat, Sprague-Dawley

CNS, parvalbumin neurons

E2

FP

Intracranial (cortex)

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

NHP, rhesus macaque

CNS, parvalbumin neurons

E2

FP

Intracranial (cortex)

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, PV-Cre

CNS, parvalbumin neurons

Brainbow

FP

2E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1038/s41467-020-18422-8

PHP.eB

POS

Human Organoid

F49B7 Retinal organoid

EF1a

Sensor, GCaMP6s

1.3E11 vg/organoid

Direct application to tissue

3-4 weeks

https://doi.org/10.1016/j.cell.2020.08.013

PHP.eB

POS

Mouse, C57BL/6J

CNS, brainstem serotonergic neurons

TPH2

Opsin, ChRmine, FP

4E11 vg/animal

RO

6 weeks

https://doi.org/10.1038/s41587-020-0679-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, purkinje neurons

L7

Opsin, ChRmine, FP

4E11 vg/animal

RO

2 months

https://doi.org/10.1038/s41587-020-0679-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, purkinje neurons

L7

Opsin, ChRmine, FP

Intracranial

2 weeks

https://doi.org/10.1038/s41587-020-0679-9

PHP.eB

POS

Mouse, CD1

CNS, neurons

hSyn1

FP

RO

https://doi.org/10.1038/s41586-020-2926-0

PHP.eB

POS

Mouse, CD1

CNS, astrocytes

GfaBC1D

FP

RO

https://doi.org/10.1038/s41586-020-2926-0

PHP.eB

POS

Mouse, Flex-tdTomato

CNS, astrocytes

GfaBC1D

CRISPR, Cas9

RO

3 weeks

https://doi.org/10.1038/s41586-020-2926-0

PHP.eB

POS

Mouse, Flex-tdTomato

CNS, astrocytes

GfaBC1D

CRISPR, sgRNA, Recombinase, Cre

RO

3 weeks

https://doi.org/10.1038/s41586-020-2926-0

PHP.eB

POS

Mouse, CD1

CNS, astrocytes

GfaBC1D

Proximity Label, Split TurboID

RO

4 weeks

https://doi.org/10.1038/s41586-020-2926-0

PHP.eB

POS

Mouse, CD1

CNS, neurons

hSyn1

Proximity Label, Split TurboID

RO

4 weeks

https://doi.org/10.1038/s41586-020-2926-0

PHP.eB

POS

Mouse, CD1

CNS, astrocytes

GfaBC1D

Proximity Label, TurboID

RO

4 weeks

https://doi.org/10.1038/s41586-020-2926-0

PHP.eB

POS

Mouse, PV-Cre

CNS, all

CBh

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.jneumeth.2020.108914

PHP.eB

POS

Mouse, PV-Cre

CNS, all

Ef1a DIO

FP, cSNAIL

4E11 vg/animal

RO

3-5 weeks

https://doi.org/10.1523/JNEUROSCI.1634-20.2020

160141

PHP.eB

POS

Mouse, Pvalb-2A-Cre Ai14

CNS, all

Ef1a DIO

FP, cSNAIL

4E11 vg/animal

RO

3-5 weeks

https://doi.org/10.1523/JNEUROSCI.1634-20.2020

160141

PHP.eB

NEG

Mouse, C57BL/6J neonate

CNS, all

CB7

FP

1E10 vg/animal

ICV

30 days

https://doi.org/10.1016/j.omtm.2020.10.011

PHP.eB

NEG

Mouse, C57BL/6J

CNS, olfactory bulb

CB7

FP

1E11 vg/animal

Intranasal

30 days

https://doi.org/10.1016/j.omtm.2020.10.011

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CB7

FP

1E11 vg/animal

Tail vein

30 days

https://doi.org/10.1016/j.omtm.2020.10.011

PHP.eB

NEG

Mouse, B6C3

CNS, all

CB7

FP

1E11 vg/animal

Tail vein

30 days

https://doi.org/10.1016/j.omtm.2020.10.011

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CB7, self complementary

FP

1E11 vg/animal

Tail vein

30 days

https://doi.org/10.1016/j.omtm.2020.10.011

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG neurons

hSyn

Chemogenetic, hM4D(Gi)

5E11 vg/site

Knee, intraarticular

3-4 weeks

https://doi.org/10.1002/art.41314

50475

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG neurons

hSyn

Chemogenetic, hM3D(Gq)

5E11 vg/site

Knee, intraarticular

3-4 weeks

https://doi.org/10.1002/art.41314

50474

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG neurons

CAG

FP

3E11 vg/site

Knee, intraarticular

3-4 weeks

https://doi.org/10.1002/art.41314

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG neurons

CAG

FP

1E12 vg/site

Knee, intraarticular

3-4 weeks

https://doi.org/10.1002/art.41314

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG sensory neurons

U6

shRNA

5E9 - 5E10 vg/animal

Intrathecal, lumbar

12 weeks

https://doi.org/10.1126/science.aaz5875

85741

PHP.S

NEG

Mouse, Swiss-Webster

PNS, trigeminal neurons, superior cervical ganglia

CBh

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-020-17936-5

PHP.S

POS

Mouse, C57BL/6J

PNS, Enteric plexus

hSyn

Inducer, tTA2

2.5E9 - 1E11 vg/animal

RO

3 weeks

https://doi.org/10.1111/nmo.14014

99120

PHP.S

POS

Mouse, C57BL/6J

PNS, Enteric plexus

TRE

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1111/nmo.14014

99131, 99114, 99113

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBA

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1089/hum.2019.186

PHP.B

NEG

Mouse, BALB/cJ

CNS, all

CBA

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1089/hum.2019.186

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBA

FP

5E10 vg/animal

ICV

https://doi.org/10.1089/hum.2019.186

PHP.B

NEG

Mouse, BALB/cJ

CNS, all

CBA

FP

5E10 vg/animal

ICV

https://doi.org/10.1089/hum.2019.186

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CMV

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41551-019-0501-5

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CMV

CRISPR, split intein CBE

4E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1038/s41551-019-0501-5

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CBh

FP

2E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1038/s41551-019-0501-5

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, all

CBh

CRISPR, split intein CBE

4E10 vg/animal

ICV

3-4 weeks

https://doi.org/10.1038/s41551-019-0501-5

137176, 137175

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, all

CBh

FP

1E10 vg/animal

ICV

3-4 weeks

https://doi.org/10.1038/s41551-019-0501-5

PHP.B

POS

Mouse, Rhodopsin-Cre Ai9

Retina

CBh

CRISPR, split intein CBE

5E9 vg/site

subretinal

3-4 weeks

https://doi.org/10.1038/s41551-019-0501-5

137176, 137175

PHP.B

POS

Mouse, Rhodopsin-Cre Ai9

Retina

CBh

FP

5E9 vg/site

subretinal

3-4 weeks

https://doi.org/10.1038/s41551-019-0501-5

PHP.eB

POS

Mouse, Npc1I1061T (c.3182T > C) neonate

CNS, all

CBh

CRISPR, split intein CBE

3E12 vg/animal

RO

up to 100 days

https://doi.org/10.1038/s41551-019-0501-5

137176, 137175

PHP.B

POS

Mouse, B6/129S neonate

CNS, all

CMV

FP

2E11 vg/animal

temporal facial vein

2 weeks

https://doi.org/10.1016/j.omtm.2020.05.021

PHP.B

POS

Mouse, B6/129S-Fdxrm1J Otop3m1J/GrsrJ neonate

CNS, all

CMV

Rescue

2E11 vg/animal

temporal facial vein

up to 4 months

https://doi.org/10.1016/j.omtm.2020.05.021

PHP.B

POS

Mouse, Hexb−/−

CNS, all

BiCBA

Rescue

1E12 vg/animal

Tail vein

up to 600 days

https://doi.org/10.1016/j.ymthe.2020.06.021

PHP.B

POS

Mouse, Hexb−/−

CNS, all

BiCBA

Rescue

3E11 vg/animal

Tail vein

up to 600 days

https://doi.org/10.1016/j.ymthe.2020.06.021

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CMV

FP

3E11 vg/animal

Tail vein

3 weeks

https://dx.doi.org/10.7150%2Fthno.46992

PHP.eB

NEG

Mouse, Apoe-/-

CNS, all

CMV

FP

3E11 vg/animal

Tail vein

3 weeks

https://dx.doi.org/10.7150%2Fthno.46992

PHP.eB

NEG

Mouse, Ldlr-/-

CNS, all

CMV

FP

3E11 vg/animal

Tail vein

3 weeks

https://dx.doi.org/10.7150%2Fthno.46992

PHP.eB

NEG

Mouse, BALB/cJ

CNS, all

CMV

FP

3E11 vg/animal

Tail vein

3 weeks

https://dx.doi.org/10.7150%2Fthno.46992

PHP.eB

POS

Mouse, C57xBALB Ldlr+/-

CNS, all

CMV

FP

3E11 vg/animal

Tail vein

3 weeks

https://dx.doi.org/10.7150%2Fthno.46992

PHP.eB

POS

Mouse, CAS9+/− fetus

CNS, excitatory neurons

CBh

FP

5E9 - 1E10 vg/animal

In utero injection

3 weeks

https://doi.org/10.1242/dev.195586

PHP.eB

POS

Mouse, CAS9+/− fetus

CNS, excitatory neurons

CBh

CRISPR, sgRNA, FP

5E9 - 1E10 vg/animal

In utero injection

3 weeks

https://doi.org/10.1242/dev.195586

91947

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, all

CBA

FP

2E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.B

POS

Mouse, C57BL/6J [B6J.129(Cg)-Igs2tm1.1(CAG-cas9*)Mmw/J

CNS, all

CBA

FP, CRISPR, sgRNA

2E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.B

POS

Mouse, C57BL/6J [B6J.129(Cg)-Igs2tm1.1(CAG-cas9*)Mmw/J

CNS, all

CBA

FP, CRISPR, sgRNA

2E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.eB

POS

Mouse, C57BL/6J [B6J.129(Cg)-Igs2tm1.1(CAG-cas9*)Mmw/J

CNS, all

CBA

FP, CRISPR, sgRNA

5E10 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.eB

POS

Mouse, C57BL/6J [B6J.129(Cg)-Igs2tm1.1(CAG-cas9*)Mmw/J

CNS, all

CBA

FP, CRISPR, sgRNA

2E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

2.5E11 vg/animal

Tail vein

4-6 weeks

https://doi.org/10.3389/fbioe.2021.679483

AAV5-PHP.B

NEG

Mouse, C57BL/6J

CNS, all

CAG

FP

2.5E11 vg/animal

Tail vein

4-6 weeks

https://doi.org/10.3389/fbioe.2021.679483

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

miRNA

1E11 vg/site

Intracranial (striatum)

4-6 weeks

https://doi.org/10.3389/fbioe.2021.679483

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

miRNA

4E12 vg/animal

Tail vein

4-6 weeks

https://doi.org/10.3389/fbioe.2021.679483

PHP.B

POS

Mouse, Ube3am−/p+ neonate

CNS, neurons

hSyn

Rescue

1.6E11 vg/animal

ICV

10-14 weeks

https://doi.org/10.1172/jci.insight.144712

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Rescue

1.6E11 vg/animal

ICV

10-14 weeks

https://doi.org/10.1172/jci.insight.144712

PHP.B

POS

Mouse, 5xFAD

CNS, neurons

hSyn

Rescue

6.25E13 vg/kg

Tail vein

2 weeks - 12 months

https://doi.org/10.1007/s13311-021-01151-1

PHP.B

POS

Mouse, 5xFAD

CNS, neurons

hSyn

FP

6.25E13 vg/kg

Tail vein

2 weeks - 12 months

https://doi.org/10.1007/s13311-021-01151-1

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Rescue

6.25E13 vg/kg

Tail vein

1,3,6 months

https://doi.org/10.1007/s13311-021-01151-1

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

FP

6.25E13 vg/kg

Tail vein

1,3,6 months

https://doi.org/10.1007/s13311-021-01151-1

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Rescue

3.12E13 vg/kg

Tail vein

1,3,6 months

https://doi.org/10.1007/s13311-021-01151-1

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Rescue

1.25E14 vg/kg

Tail vein

1,3,6 months

https://doi.org/10.1007/s13311-021-01151-1

PHP.B

POS

Mouse, Grin1flox/flox

CNS, astrocytes

GfaBC1D

Sensor, GCaMP3

1.4E11 vg/animal

RO

3 weeks

DOI: 10.1126/sciadv.abk1378

PHP.B

POS

Mouse, C57BL/6J

CNS, astrocytes

GfaBC1D

Sensor, GCaMP3

1.4E11 vg/animal

RO

3 weeks

DOI: 10.1126/sciadv.abk1378

PHP.B

POS

Mouse, AppNL-G-F

CNS, all

CAG

Rescue

1E12 vg/animal

Tail vein

12 months

https://doi.org/10.15252/emmm.201809824

PHP.B

POS

Mouse, C57BL/6J neonate

Cochlea neurons

hSyn

Sensor, vf-Chrimson

8.7E9 vg/animal

scala tympani

https://doi.org/10.15252/emmm.202013391

PHP.eB

POS

Mouse, C57BL/6J neonate

Cochlea neurons

hSyn

Sensor, vf-Chrimson-ES/TS

1.1E10 vg/animal

scala tympani

https://doi.org/10.15252/emmm.202013391

PHP.B

POS

Mouse, VGAT)-tdTomato

CNS, neurons

CBh

FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neulet.2021.135956

PHP.eB

POS

Mouse, VGAT)-tdTomato

CNS, neurons

mCaMKII

FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neulet.2021.135956

PHP.eB

POS

Mouse, VGAT)-tdTomato

CNS, neurons

SynI-mCMV

FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neulet.2021.135956

PHP.eB

POS

Mouse, VGAT)-tdTomato

CNS, neurons

NSE

FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neulet.2021.135956

PHP.eB

POS

Mouse, VGAT)-tdTomato

CNS, neurons

CBh

FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neulet.2021.135956

PHP.eB

POS

Mouse, KO ARSA

CNS, all

CAG

Rescue

5E11 vg/animal

RO

3 months

https://doi.org/10.3389/fnmol.2021.677895

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

Syn1

FP

3E11 vg/animal

ICV

4 weeks

https://doi.org/10.1089/hum.2020.301

PHP.B

NHP, rhesus macaque

CNS, neurons

Syn1

FP

2-4E12 vg/kg

ICV

4-4.5 weeks

https://doi.org/10.1089/hum.2020.301

PHP.eB

Cat

CNS, all

CAG

FP

5E8 vg/site

Intracranial (cortex)

7 days

https://doi.org/10.1016/j.isci.2021.102685

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

5E8 vg/site

Intracranial (cortex)

https://doi.org/10.1016/j.isci.2021.102685

PHP.eB

NHP, rhesus macaque

CNS, all

CAG

FP

2E9 vg/site

Intracranial (cortex)

7 days

https://doi.org/10.1016/j.isci.2021.102685

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CMV

FP

4.8E9 vg/site

Intracranial (anterior cingulate, cortex, cerebellum)

30 days

https://doi.org/10.1038/s41434-021-00272-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

X on

FP

2E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41586-021-03770-2

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

X on

Rescue

2E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41586-021-03770-2

PHP.eB

NHP, macaca nemestrina

CNS, parvalbumin neurons

3xSP10ins-eHGT_359h-minRho*

FP

5E10 vg/site

Intracranial (cortex)

64 days

https://dx.doi.org/10.3791/62546

163504

PHP.eB

NHP, macaca nemestrina

CNS, cortex L5 neurons

eHGT_453m-minBglobin

FP

5E10 vg/site

Intracranial (cortex)

113 days

https://dx.doi.org/10.3791/62546

164453

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

Sensor, iGlow

7E9 vg/site

Intracranial (hippocampus)

2 weeks

https://doi.org/10.1242/jcs.255455

PHP.eB

POS

Mouse, Scn2agt/gt

CNS, all

EF1a

Recombinase, FLPo, FP

2E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.celrep.2021.109495

PHP.eB

POS

Mouse, Scn2agt/gt

CNS, all

EF1a

FP

2E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.celrep.2021.109495

PHP.eB

POS

Mouse, Scn2agt/gt

CNS, all

EF1a

Recombinase, FLPo, FP

5E7 vg/site

Intracranial (striatum)

3 weeks

https://doi.org/10.1016/j.celrep.2021.109495

PHP.eB

POS

Mouse, Scn2agt/gt

CNS, all

EF1a

FP

5E7 vg/site

Intracranial (striatum)

3 weeks

https://doi.org/10.1016/j.celrep.2021.109495

PHP.eB

POS

Mouse, Cabp2–/– neonate

Cochlea

hCMV hBA

Rescue, FP

8E9 vg/site

scala tympani

5-8 weeks

https://doi.org/10.3389/fnmol.2021.689415

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

5E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.3389/fneur.2021.685802

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

5E11 vg/animal

Tail vein

4 weeks

https://doi.org/10.3389/fneur.2021.685802

PHP.eB

NEG

Mouse, C57BL/6J

CNS, all

CAG

FP

5E10 vg/animal

Tail vein

4 weeks

https://doi.org/10.3389/fneur.2021.685802

PHP.eB

NEG

Mouse, C57BL/6J

CNS, all

CAG

FP

5E9 vg/animal

Tail vein

4 weeks

https://doi.org/10.3389/fneur.2021.685802

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

CamKIIa

FP

5E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.3389/fneur.2021.685802

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

FP

5E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.3389/fneur.2021.685802

PHP.eB

NHP, macaca fascicularis

CNS, all

CBA

FP

9E9 vg/site

Intracranial (putamen)

28 - 30 days

https://doi.org/10.1016/j.ymthe.2021.07.010

PHP.eB

NHP, macaca fascicularis

CNS, all

CBA

FP

3.2E11 vg/animal

ICV

28 - 30 days

https://doi.org/10.1016/j.ymthe.2021.07.010

PHP.eB

NHP, macaca fascicularis

CNS, all

CBA

FP

3.2E11 vg/animal

ICM

28 - 30 days

https://doi.org/10.1016/j.ymthe.2021.07.010

PHP.eB

NHP, macaca fascicularis

CNS, all

CBA

FP

3.2E11 vg/animal

Intrathecal, lumbar

28 - 30 days

https://doi.org/10.1016/j.ymthe.2021.07.010

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1128/JVI.01164-21

AAV1-PHP.B

NEG

Mouse, C57BL/6J

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1128/JVI.01164-21

PHP.B

POS

Mouse, Rosa26-Cas9 knockin

CNS, all

4x U6

CRISPR, sgRNA

6E9 vg/animal

RO

2 months

https://doi.org/10.1016/j.cmet.2021.06.013

PHP.eB

POS

Mouse, Ndufs4-/-

CNS, all

EF1a

Rescue

6E12 vg/animal

RO

up to 280 days

https://doi.org/10.1016/j.cmet.2021.06.013

PHP.eB

POS

Mouse, Ndufs4-/-

CNS, all

EF1a

FP

6E12 vg/animal

RO

up to 280 days

https://doi.org/10.1016/j.cmet.2021.06.013

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

Syn

Sensor, GCaMP6s

IV

https://doi.org/10.1038/s41467-021-26255-2

PHP.B

NEG

Mouse, TgCRND8

CNS, cortex, striatum, thalamus

smCBA

FP

1E11 vg/animal

Tail vein, focused ultrasound FUS

3 weeks

https://doi.org/10.1016/j.omtm.2021.10.001

PHP.B

Mouse, TgCRND8

CNS, cortex, striatum, thalamus

smCBA

FP

1E10 vg/animal

Tail vein, focused ultrasound FUS

3 weeks

https://doi.org/10.1016/j.omtm.2021.10.001

PHP.B

NEG

Mouse, BALB/cJ

CNS, cortex, striatum

smCBA

FP

1E11 vg/animal

Tail vein, focused ultrasound FUS

3 weeks

https://doi.org/10.1016/j.omtm.2021.10.001

PHP.eB

NEG

Mouse, C57BL/6J

Ef1a DIO

FP, cSNAIL

4E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1523/JNEUROSCI.2534-20.2021

PHP.eB

POS

Mouse, Pvalb-Cre

CNS, parvalbumin neurons

Ef1a DIO

FP, cSNAIL

4E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1523/JNEUROSCI.2534-20.2021

PHP.eB

POS

Mouse, Sst-Cre

CNS, somatostatin neurons

Ef1a DIO

FP, cSNAIL

4E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1523/JNEUROSCI.2534-20.2021

PHP.eB

POS

Mouse, Drd1-Cre

CNS, dopaminergic neurons

Ef1a DIO

FP, cSNAIL

4E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1523/JNEUROSCI.2534-20.2021

PHP.eB

POS

Mouse, Adora2a-Cre

CNS, stiatopallidal neurons

Ef1a DIO

FP, cSNAIL

4E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1523/JNEUROSCI.2534-20.2021

PHP.B

NHP, rhesus macaque

CNS, all

CAG

FP

1E12 vg/animal

Intrathecal, lumbar

2 months

https://doi.org/10.3389/fbioe.2021.762209

PHP.eB

NHP, rhesus macaque

CAG

FP

1E12 vg/animal

Intrathecal, lumbar

2 months

https://doi.org/10.3389/fbioe.2021.762209

PHP.eB

POS

Mouse, UCP1-Cre

CNS, hypothalamus

FP

8E10 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.molmet.2021.101405

PHP.eB

POS

Mouse, Oxtr 1×PA-iCre/+

CNS, Oxtr neurons

CBh FLEX

FP

2.5E11 vg/animal

RO

4 weeks

https://doi.org/10.1523/ENEURO.0423-21.2022

PHP.eB

POS

Mouse, C57BL/6J

CNS, spinal cord neurons

hSyn

Rescue, FP

3E11 vg/animal

Intrathecal, lumbar

12 weeks

https://doi.org/10.1186/s13024-021-00511-x

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG neurons

hSyn

Rescue, FP

3E11 vg/animal

Intrathecal, lumbar

12 weeks

https://doi.org/10.1186/s13024-021-00511-x

PHP.eB

POS

Mouse, Sarm1 KO

CNS, spinal cord neurons

hSyn

Rescue, FP

3E11 vg/animal

Intrathecal, lumbar

12 weeks

https://doi.org/10.1186/s13024-021-00511-x

PHP.S

POS

Mouse, Sarm1 KO

PNS, DRG neurons

hSyn

Rescue, FP

3E11 vg/animal

Intrathecal, lumbar

12 weeks

https://doi.org/10.1186/s13024-021-00511-x

PHP.eB

POS

Mouse, fosGFP

CNS, S1 neurons

Sensor, RCaMP1.07

1E9 vg/site

Intracranial (cortex)

1 week

DOI: 10.1126/science.abl5981

PHP.eB

POS

Mouse, C57BL/6J

CNS, S1 neurons

Sensor, RCaMP1.07

1E9 vg/site

Intracranial (cortex)

1 week

DOI: 10.1126/science.abl5981

PHP.eB

POS

Mouse, Thy1-Cre

CNS, S1 neurons

hSyn DIO

FP, Rescue, Retrograde tracing

Intracranial (cortex)

3 weeks

https://doi.org/10.1186/s13041-022-00898-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, S1 neurons

hSyn

FP, Rescue, Retrograde tracing

Intracranial (cortex)

3 weeks

https://doi.org/10.1186/s13041-022-00898-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

FP, Rescue, Retrograde tracing

4E11 vg/animal

IV

3 weeks

https://doi.org/10.1186/s13041-022-00898-8

PHP.eB

POS

Mouse, VGAT-Cre

CNS, GABAergic neurons

hSyn DIO

FP, Rescue, Retrograde tracing

4E11 vg/animal

IV

3 weeks

https://doi.org/10.1186/s13041-022-00898-8

PHP.eB

POS

Mouse, VGAT-Cre

CNS, GABAergic neurons

hSyn

FP, Rescue, Retrograde tracing

4E11 vg/animal

IV

3 weeks

https://doi.org/10.1186/s13041-022-00898-8

PHP.eB

POS

Mouse, Z-Q175-KI

CNS, striatum astrocytes

GfaBS1D

FP, Rescue

1E9 vg/site

Intracranial (striatum)

3-5 weeks

https://doi.org/10.3389/fncel.2021.792652

PHP.eB

POS

Mouse, Z-Q175-KI

CNS, astrocytes

GfaBS1D

FP, Rescue

2-4E11 vg/animal

IV

https://doi.org/10.3389/fncel.2021.792652

PHP.eB

POS

Mouse, C57BL/6J

CNS, endothelial pericytes

CAG

FP

4E11 vg/animal

RO or tail vein

2 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, C57BL/6J

CNS, endothelial pericytes

CAG

FP, Rescue

4E11 vg/animal

RO or tail vein

2 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, endothelial pericytes

CAG

FP

4E10 vg/animal

RO or tail vein

3 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, endothelial pericytes

CAG

FP, Rescue

4E10 vg/animal

RO or tail vein

3 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, BAT-GAL

CNS, endothelial pericytes

CAG

FP

4E11 vg/animal

RO or tail vein

2 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, BAT-GAL

CNS, endothelial pericytes

CAG

FP, Rescue

4E11 vg/animal

RO or tail vein

2 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, BAT-GAL

CNS, endothelial pericytes

CAG

FP

4E10 vg/animal

RO or tail vein

3 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, BAT-GAL

CNS, endothelial pericytes

CAG

FP, Rescue

4E10 vg/animal

RO or tail vein

3 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn DIO, fDIO

FP

1E10 vg/animal

RO

18 days

https://doi.org/10.1038/s42003-022-03096-3

55650

PHP.eB

POS

Mouse, Crabp1 KO

CNS, spinal cord, neuromuscular junction

hSyn

Rescue, FP

3 months

https://doi.org/10.1038/s41418-022-00959-4

PHP.eB

POS

Mouse, Crabp1 KO

CNS, spinal cord, neuromuscular junction

hSyn

FP

3 months

https://doi.org/10.1038/s41418-022-00959-4

PHP.eB

POS

Mouse, mc1Bth/+ neonate

Cochlea

CMV, U6

CRISPR, CasRx sgRNA

5E9 vg/site

Round window membrane

2 weeks

https://doi.org/10.1038/s41392-022-00893-4

PHP.eB

POS

Mouse, Tmc1+/+

Cochlea

CMV, U6

CRISPR, CasRx sgRNA

5E9 vg/site

Round window membrane

2 weeks

https://doi.org/10.1038/s41392-022-00893-4

PHP.eB

POS

Mouse, B6/C3H neonate

CNS, all

CMV, U6

Rescue sup-tRNA, FP

1E11 vg/animal

IV

10 weeks

https://doi.org/10.1038/s41586-022-04533-3

PHP.eB

POS

Mouse, B6/C3H neonate

CNS, all

CMV, U6

Rescue sup-tRNA, FP

2E11 vg/animal

IV

10 weeks

https://doi.org/10.1038/s41586-022-04533-3

PHP.eB

POS

Mouse, Fmr1-KO

CNS, all

CMV

Rescue

5E11 vg/animal

RO

4 or 8 weeks

https://doi.org/10.15252/emmm.202114649

PHP.eB

Mouse, C57BL/6J

Muscle

CMV

FP

1E12 vg/animal

Intramuscular

4 weeks

https://doi.org/10.1016/j.genrep.2021.101227

PHP.eB

POS

Mouse, Per2fl/fl

CNS, astrocytes

GFAP

Recombinase, iCre, FP

1E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41598-021-91770-7

PHP.eB

POS

Mouse, Per2fl/fl

CNS, astrocytes

CAG

FP

1E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41598-021-91770-7

PHP.eB

NEG

Mouse, Per2fl/fl

CNS, astrocytes

GFAP

Recombinase, iCre, FP

1E11 vg/animal

Intraperitoneal, IP

3 weeks

https://doi.org/10.1038/s41598-021-91770-7

PHP.eB

POS

Mouse, Per2fl/fl

CNS, astrocytes

GFAP

Recombinase, iCre, FP

1E11 vg/animal

Intraperitoneal, IP

2 months

https://doi.org/10.1038/s41598-021-91770-7

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Rescue, FP, Epitope

5E11 vg/animal

RO

3 weeks

DOI: 10.7554/eLife.65417

PHP.eB

POS

Mouse, C57BL/6J

CNS, excitatory neurons

CamKIIa

FP

1E11 vg/animal

IV

3 weeks

https://doi.org/10.1038/s41598-021-95930-7

PHP.eB

POS

Mouse, C57BL/6J

CNS, gabaergic interneurons

mDLX

FP

1E11 vg/animal

IV

3 weeks

https://doi.org/10.1038/s41598-021-95930-7

83900

PHP.eB

POS

Mouse, 3xTg-AD

CNS, all

CMV

FP

1E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.1016/j.bbr.2021.113673

PHP.eB

POS

Mouse, 3xTg-AD

CNS, all

CMV

FP, Rescue

1E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.1016/j.bbr.2021.113673

PHP.eB

POS

Mouse, C57BL/6JRcc neonates

CNS, hippocampus

U6, hSyn

shRNA, FP

1-2E9 vg/site

ICV

3 weeks

https://doi.org/10.1523/JNEUROSCI.0908-21.2022

PHP.eB

POS

Rat, Sprague-Dawley

CNS, all

CAG

FP

6E11 vg/animal

ICM

1 month

https://doi.org/10.1038/s41434-021-00244-y

37825

PHP.eB

NEG

Rat, Sprague-Dawley

CNS, all

CAG

FP

6E10 vg/animal

ICM

1 month

https://doi.org/10.1038/s41434-021-00244-y

37825

PHP.B

POS

Mouse, Mcoln1−/−

CNS, all

CMV

Rescue, FP

1E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.1093/hmg/ddab093

PHP.B

POS

Mouse, Mcoln1−/+

CNS, all

CMV

Rescue, FP

1E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.1093/hmg/ddab093

PHP.eB

POS

Mouse, Mmut−/− neonate

CNS, neurons

CamKIIa

Rescue

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2021.04.005

PHP.eB

POS

Mouse, Mmut−/−

CNS, neurons

CBA

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2021.04.005

PHP.eB

POS

Mouse, Mmut+/− neonate

CNS, neurons

CamKIIa

Rescue

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2021.04.005

PHP.S

POS

Mouse, C57BL/6J

PNS, trigeminal ganglia

CAG

FP

0.7 - 5E11 vg/animal

RO

3 weeks

https://doi.org/10.3389/fnins.2021.715954

PHP.S

POS

Mouse, PV-RTM

PNS, Lumbar DRG

hSyn

FP

1-2E11 vg/animal

Intrathecal, lumbar

2 weeks

https://doi.org/10.1016/j.ymthe.2021.04.023

PHP.S

POS

Mouse, PV-RTM

PNS, Lumbar DRG

hSyn

FP

1-2E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.1016/j.ymthe.2021.04.023

PHP.S

POS

Mouse, PV-Cre

PNS, Lumbar DRG

hSyn FLEX

Chemogenetic, hM3Dq, FP

1-2E11 vg/animal

Intrathecal, lumbar

8 weeks

https://doi.org/10.1016/j.ymthe.2021.04.023

PHP.S

NEG

Mouse, C57BL/6J

PNS, schwann cells

CAG

FP

9E10 vg/animal

Intrathecal

6 weeks

https://doi.org/10.1038/s41598-021-02694-1

PHP.S

NEG

Mouse, C57BL/6J

PNS, schwann cells

CAG

FP

1E12 vg/animal

Tail vein

6 weeks

https://doi.org/10.1038/s41598-021-02694-1

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, neurons

hSyn, U6

FP, shRNA

ICV

https://doi.org/10.1073/pnas.2001679118

PHP.eB

POS

Mouse, LSL-Cas9

CNS, neurons

hSyn, U6

CRISPR, sgRNA, Recombinase, Cre

5E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.1016/j.omtm.2021.02.012

PHP.eB

POS

Mouse, LSL-Cas9

CNS, astrocytes

GFAP, U6

CRISPR, sgRNA, Recombinase, Cre

5E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.1016/j.omtm.2021.02.012

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

FP

4E11 vg/animal

Tail vein

4 weeks

https://doi.org/10.1016/j.omtm.2020.12.006

PHP.eB

POS

Mouse, Vglut2-Cre

CNS, amygdala

hSyn

FP

1.2E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41586-021-03413-6

PHP.eB

POS

Mouse, neonate

CNS, all

CMV

Rescue, FP

2E11 vg/animal

Intracardiac

https://doi.org/10.1007/s10565-021-09601-4

PHP.B

POS

Mouse, C57BL/6J

Cochlea

hSyn

Opsin, vf-Chrimson

1E10 vg/site

Round window membrane

https://doi.org/10.15252/emmm.202013391

PHP.eB

POS

Mouse, C57BL/6J

Cochlea

hSyn

Opsin, vf-Chrimson-ES/TS

1E10 vg/site

Round window membrane

https://doi.org/10.15252/emmm.202013391

PHP.eB

POS

Mouse, KO ARSA

CNS, all

CAG

Rescue

5E11 vg/animal

RO

3 months

https://doi.org/10.3389/fnmol.2021.677895

PHP.eB

POS

Mouse, SstCre/+ neonate

CNS, somatostatin neurons

hSyn DIO

Chemogenetic, hM4D(Gi), FP

2E10 vg/animal

ICV

9 weeks

https://doi.org/10.1093/ijnp/pyab002

44362

PHP.eB

POS

Mouse, SstCre/+ neonate

CNS, somatostatin neurons

hSyn DIO

FP

2E10 vg/animal

ICV

9 weeks

https://doi.org/10.1093/ijnp/pyab002

50459

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CMV

FP

3E9 vg/site

Intracranial (cortex, cerebellum)

https://doi.org/10.1038/s41434-021-00272-8

165441, 165442, 165443

PHP.S

POS

Mouse, Cck-Ires-Cre

PNS, myenteric neurons

CAG DIO

FP

5.7E11 vg/animal

Tail vein

2-3 weeks

https://doi.org/10.1038/s41593-020-00736-x

PHP.B

POS

Mouse, H11-Cas9 neonate

CNS, all

CAG U6

FP, CRISPR, sgRNA

1E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00224-2

PHP.B

POS

Mouse, H11-Cas9 neonate

CNS, all

CAG U6

FP, CRISPR, sgRNA

2E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00224-2

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

mGAD65

FP

5E12 vg/animal

RO

3 weeks

https://doi.org/10.1186/s13041-021-00746-1

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

mDlx

FP

5E12 vg/animal

RO

3 weeks

https://doi.org/10.1186/s13041-021-00746-1

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

mGAD65

FP

1E11 vg/site

Intrcranial (cerebellum)

https://doi.org/10.1186/s13041-021-00746-1

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

mDlx

FP

1E11 vg/site

Intrcranial (cerebellum)

https://doi.org/10.1186/s13041-021-00746-1

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

mGAD65

FP

3E12 vg/animal

RO

3 weeks

https://doi.org/10.1186/s13041-021-00746-1

PHP.B

POS

Mouse, H11-Cas9 neonate

CNS, all

CBA U6

FP, CRISPR, sgRNA

5E10 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.eB

POS

Mouse, H11-Cas9 neonate

CNS, all

CBA U6

FP, CRISPR, sgRNA

5E10 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.B

POS

Mouse, H11-Cas9 neonate

CNS, all

CBA U6

FP, CRISPR, sgRNA

2E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.eB

POS

Mouse, H11-Cas9 neonate

CNS, all

CBA U6

FP, CRISPR, sgRNA

2E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBh

miRNA

1E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.neuroscience.2020.04.004

AAV9.452sub.LUNG1

POS

Mouse, C57BL/6J

Lung, alveolar type 2

CAG

FP

5E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.omtm.2022.07.010

104061

AAV9.452sub.LUNG1

POS

Mouse, C57BL/6J

Lung, alveolar type 2

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2022.07.010

104061

Cu64labeled-PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

7E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.biomaterials.2022.121701

Cu64labeled-CAP-B10

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

7E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.biomaterials.2022.121701

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

EF1a

PET reporter

2E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.biomaterials.2022.121701

PHP.eB

POS

Mouse, C57BL/6J

Liver

CAG

FP

7E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.biomaterials.2022.121701

CAP-B10

POS

Mouse, C57BL/6J

Liver

CAG

FP

7E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.biomaterials.2022.121701

PHP.S

NEG

Mouse, C57BL/6J

PNS, nodose ganglion

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS1

POS

Mouse, C57BL/6J

PNS, nodose ganglion

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

POS

Mouse, C57BL/6J

PNS, nodose ganglion

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

PHP.S

NEG

Mouse, C57BL/6J

PNS, DRG

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS1

POS

Mouse, C57BL/6J

PNS, DRG

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

POS

Mouse, C57BL/6J

PNS, DRG

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

PHP.S

NEG

Mouse, C57BL/6J

PNS, enteric ganglia

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS1

NEG

Mouse, C57BL/6J

PNS, enteric ganglia

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

NEG

Mouse, C57BL/6J

PNS, enteric ganglia

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

PHP.S

NEG

Mouse, C57BL/6J

PNS, enteric ganglia

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS1

NEG

Mouse, C57BL/6J

PNS, enteric ganglia

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

POS

Mouse, C57BL/6J

PNS, enteric ganglia

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

POS

Mouse, C57BL/6J

PNS, colon

hSyn

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

51506

MaCPNS2

POS

Mouse, C57BL/6J

PNS, colon

hSyn

FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

51506

MaCPNS2

POS

Mouse, C57BL/6J

PNS, colon

hSyn

FP

7E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

51506

MaCPNS1

POS

Mouse, C57BL/6J

PNS, nodose ganglion

CAG

Sensor, GCaMP8s

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

162380

MaCPNS1

POS

Mouse, TRPV1-Cre neonate

PNS, DRG

hSyn DIO

Chemogenetic, hM3Dq, FP

3E11 vg/animal

Intraperitoneal, IP

6 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

44361

MaCPNS1

POS

Rat, Sprague-Dawley

PNS

hSyn

FP

2E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

POS

Rat, Sprague-Dawley

PNS

hSyn

FP

2E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS1

POS

NHP, marmoset

CNS, all

CAG

FP

3.5E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

POS

NHP, marmoset

CNS, all

CAG

FP

3.5E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS1

POS

NHP, marmoset

PNS, DRG

CAG

FP

3.5E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

POS

NHP, marmoset

PNS, DRG

CAG

FP

3.5E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS1

POS

NHP, marmoset

PNS, enteric ganglia

CAG

FP

3.5E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

POS

NHP, marmoset

PNS, enteric ganglia

CAG

FP

3.5E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS1

POS

NHP, rhesus macaque neonate

CNS, all

CAG

FP

2.5E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

POS

NHP, rhesus macaque neonate

CNS, all

CAG

FP

2.5E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS1

POS

NHP, rhesus macaque neonate

PNS, DRG

CAG

FP

2.5E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

POS

NHP, rhesus macaque neonate

PNS, DRG

CAG

FP

2.5E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS1

POS

NHP, rhesus macaque neonate

PNS, enteric ganglia

CAG

FP

2.5E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

POS

NHP, rhesus macaque neonate

PNS, enteric ganglia

CAG

FP

2.5E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

PHP.S

NEG

Mouse, C57BL/6J

PNS, DRG

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS1

POS

Mouse, C57BL/6J

PNS, DRG

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

NEG

Mouse, C57BL/6J

CNS, all

hSyn

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

NEG

Mouse, C57BL/6J

CNS, all

hSyn

FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

NEG

Mouse, C57BL/6J

CNS, all

hSyn

FP

7E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

hSyn

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS1

POS

Mouse, C57BL/6J neonate

PNS, DRG

hSyn

FP

3E11 vg/animal

Intraperitoneal, IP

6 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

POS

Mouse, C57BL/6J neonate

PNS, DRG

hSyn

FP

3E11 vg/animal

Intraperitoneal, IP

6 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS1

POS

Rat, Sprague-Dawley

CNS, all

hSyn

FP

2E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

MaCPNS2

POS

Rat, Sprague-Dawley

CNS, all

hSyn

FP

2E13 vg/kg

IV

3 weeks

https://doi.org/10.1016/j.neuron.2022.05.003

PHP.eB

POS

Mouse, EMX1-Cre

CNS, neuons

hSyn DIO

Rescue, FP

RO

4 weeks

https://doi.org/10.1038/s42003-022-03813-y

PHP.eB

POS

Mouse, IRSp53-cKO EMX1-Cre

CNS, neurons

hSyn DIO

Rescue, FP

RO

4 weeks

https://doi.org/10.1038/s42003-022-03813-y

PHP.eB

POS

Mouse, EMX1-Cre

CNS, neurons

hSyn DIO

FP

RO

4 weeks

https://doi.org/10.1038/s42003-022-03813-y

PHP.eB

POS

Mouse, IRSp53-cKO EMX1-Cre

CNS, neurons

hSyn DIO

FP

RO

4 weeks

https://doi.org/10.1038/s42003-022-03813-y

PHP.eB

POS

Mouse, C57BL/6J

CNS, excitatory neurons

CamKIIa

Proximity Label, TurboID

3E11 vg/animal

RO

4 weeks

doi: 10.1021/acs.analchem.1c05212

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

Proximity Label, TurboID

3E11 vg/animal

RO

4 weeks

doi: 10.1021/acs.analchem.1c05212

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

shRNA, FP

2E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.neuroscience.2022.08.023

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

2E11 vg/animal

IV

5 weeks

https://doi.org/10.1038/s41467-022-33932-3

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

shRNA, FP

2E11 vg/animal

IV

5 weeks

https://doi.org/10.1038/s41467-022-33932-3

PHP.eB

POS

Mouse, CX3CR1+/GFP

CNS, astrocytes

GFAP

FP

2E11 vg/animal

IV

5 weeks

https://doi.org/10.1038/s41467-022-33932-3

PHP.eB

POS

Mouse, RUBICON−/−

CNS, astrocytes

GFAP

FP

2E11 vg/animal

IV

5 weeks

https://doi.org/10.1038/s41467-022-33932-3

PHP.eB

POS

Mouse, Klb-CRE

CNS, neurons

hSyn DIO

Chemogenetic, hM3Dq, FP

RO

https://doi.org/10.1016/j.molmet.2022.101564

44361

PHP.eB

POS

Mouse, Klb-CRE

CNS, neurons

CAG FLEX

FP

RO

https://doi.org/10.1016/j.molmet.2022.101564

28306

PHP.eB

POS

Mouse, Sim1-cre

CNS, neurons

CAG FLEX

Rescue

2.5E11 vg/animal

IV

4 months

https://doi.org/10.1038/s41467-022-33367-w

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

CAG FLEX

Rescue

2.5E11 vg/animal

IV

4 months

https://doi.org/10.1038/s41467-022-33367-w

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CMV

FP

1.5E13 vg/kg

RO

2 weeks

https://doi.org/10.3389/fnmol.2022.947490

PHP.eB

POS

Mouse, C57BL/6J

CNS, cerebellum

CMV

FP

4E9 vg/mouse

Intraparenchymal

4 weeks

https://doi.org/10.3389/fnmol.2022.947490

PHP.eB

POS

Mouse, C57BL/6J

CNS, cerebellum

CMV

FP

4E9 vg/mouse

Intraparenchymal

7 weeks

https://doi.org/10.3389/fnmol.2022.947490

PHP.eB

POS

Mouse, C57BL/6J

CNS

FP

5E11 vg/animal

Tail vein

20 weeks

https://doi.org/10.1007/s00018-022-04518-5

PHP.eB

POS

Mouse, C57BL/6J

CNS

Rescue, FP

5E11 vg/animal

Tail vein

20 weeks

https://doi.org/10.1007/s00018-022-04518-5

PHP.eB

POS

Mouse, C57BL/6J

CNS

Rescue, FP

5E11 vg/animal

Tail vein

20 weeks

https://doi.org/10.1007/s00018-022-04518-5

PHP.eB

POS

Mouse, Fgf21-P2A-CRE

CNS, all

CAG FLEX

FP

RO

2 weeks

https://doi.org/10.1016/j.celrep.2022.111239

PHP.eB

POS

Mouse, FGF21fl/fl

CNS, neurons

hSyn

Recombinase, Cre

RO

2 weeks

https://doi.org/10.1016/j.celrep.2022.111239

PHP.eB

POS

Mouse, FGF21fl/fl

CNS, all

CMV

FP

RO

2 weeks

https://doi.org/10.1016/j.celrep.2022.111239

PHP.eB

POS

Mouse, FGF21fl/fl

CNS, all

CMV

Recombinase, Cre

RO

2 weeks

https://doi.org/10.1016/j.celrep.2022.111239

PHP.eB

POS

Mouse, Myo6C442Y/+ neonate

Inner ear

EF1a

CRISPR, mxABE, sgRNA

1.4E10 vg/site

Cochlea

2 weeks

https://doi.org/10.1126/scitranslmed.abn0449

PHP.B

POS

Mouse, APP23.tau−/−

CNS, neurons

hSyn

Rescue

1E10 vg/site

Intracranial (cortex, hippocampus)

https://doi.org/10.1126/sciadv.abl8809

PHP.S

POS

Mouse, Nav1.8Cre het

PNS, all

mini-Cav3.2 FLEX

Chemogenetic, hM3Dq

5E10 vg/animal

Intrathecal, lumbar

8 weeks

https://doi.org/10.1126/sciadv.abo7566

PHP.eB

POS

Mouse, 5xFAD

CNS, parvalbumin neurons

E2

FP

Intracranial (cortex)

https://doi.org/10.7554/eLife.75316

135631

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons

E2

FP

Intracranial (cortex)

https://doi.org/10.7554/eLife.75316

135631

PHP.eB

POS

Mouse, 5xFAD

CNS, parvalbumin neurons

E2

FP

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.7554/eLife.75316

135631

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons

E2

FP

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.7554/eLife.75316

135631

PHP.eB

POS

Mouse, C57BL/6J

CNS, purkinje neurons

L7 tTA TRE

Rescue

Intracranial (cerebellum)

8 days

https://doi.org/10.1038/s41467-022-30828-0

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn tTA TRE

Rescue

Intracranial (cerebellum)

8 days

https://doi.org/10.1038/s41467-022-30828-0

PHP.eB

POS

Mouse, Rbp4-Cre KL100

CNS, L5 cortical pyramidal neurons

CAG FLEX

Sensor, GCaMP7s

2E13 vg/kg

RO

1-3 weeks

https://doi.org/10.1016/j.neuron.2022.03.032

PHP.eB

POS

Mouse, Gad2-Cre

CNS, L1 cortical neurons

CAG FLEX

Sensor, GCaMP7s

2E13 vg/kg

RO

1-3 weeks

https://doi.org/10.1016/j.neuron.2022.03.032

PHP.eB

POS

Mouse, Cux2-Cre

CNS, L2/3 cortical neurons

CAG FLEX

Sensor, GCaMP7s

2E13 vg/kg

RO

1-3 weeks

https://doi.org/10.1016/j.neuron.2022.03.032

PHP.eB

POS

Mouse, Scnn1-Cre

CNS, L4 cortical neurons

CAG FLEX

Sensor, GCaMP7s

2E13 vg/kg

RO

1-3 weeks

https://doi.org/10.1016/j.neuron.2022.03.032

PHP.eB

POS

Mouse, Ntsr-Cre

CNS, L6 cortical neurons

CAG FLEX

Sensor, GCaMP7s

2E13 vg/kg

RO

1-3 weeks

https://doi.org/10.1016/j.neuron.2022.03.032

PHP.eB

POS

Mouse, Rbp4-Cre

CNS, neurons

Syn FLEX tTA TRE

Rescue

2E13 vg/kg

RO

1-3 weeks

https://doi.org/10.1016/j.neuron.2022.03.032

PHP.eB

POS

Mouse, Sun1-GFP

retina, astrocytes

GFAP

Recombinase, Cre

2E9 vg/site

subretinal

4 weeks

https://doi.org/10.1016/j.celrep.2022.110960

PHP.eB

POS

Mouse, Sun1-GFP

retina, astrocytes

GFAP

CRISPR, CasRx sgRNA

8E9 vg/site

subretinal

4 weeks

https://doi.org/10.1016/j.celrep.2022.110960

PHP.eB

POS

Mouse, 129S2/SvHsd

retina

CMV

FP

5E10 vg/animal

tail vein

1 month

https://doi.org/10.1016/j.omtm.2022.03.016

PHP.eB

POS

Mouse, 129S2/SvHsd

retina

CMV

FP

7.5E8 vg/site

intravitreal

1 month

https://doi.org/10.1016/j.omtm.2022.03.016

PHP.eB

POS

Mouse, 129S2/SvHsd

retina

CMV

FP

6E6 vg/site

subretinal

1 month

https://doi.org/10.1016/j.omtm.2022.03.016

PHP.eB

POS

Mouse, 129S2/SvHsd

retina

CMV

FP

3E7 vg/site

subretinal

1 month

https://doi.org/10.1016/j.omtm.2022.03.016

PHP.eB

NEG

Mouse, 129S2/SvHsd

retina

CMV

FP

1.5E8 vg/site

subretinal

1 month

https://doi.org/10.1016/j.omtm.2022.03.016

PHP.eB

NEG

Mouse, 129S2/SvHsd

retina

CMV

FP

7.5E8 vg/site

subretinal

1 month

https://doi.org/10.1016/j.omtm.2022.03.016

PHP.eB

POS

Mouse, APP/PS1

CNS, astrocytes

GfaABC1D

FP

RO

2 weeks

https://doi.org/10.1126/science.adc9020

PHP.eB

POS

Mouse, C57BL/6NTac

CNS, astrocytes

GfaABC1D

FP

RO

2 weeks

https://doi.org/10.1126/science.adc9020

PHP.S

POS

Mouse, C57BL/6J

PNS, enteric ganglia

hSyn

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.3389/fnana.2022.884280

PHP.S

POS

Mouse, C57BL/6J

PNS, enteric ganglia

CAG DIO

FP

3.3E11 vg/animal

RO

3 weeks

https://doi.org/10.3389/fnana.2022.884280

PHP.S

POS

Mouse, C57BL/6J

PNS, enteric ganglia

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.3389/fnana.2022.884280

PHP.S

Mouse, C57BL/6J

PNS, enteric ganglia

CAG

FP

3.3E11 vg/animal

RO

3 weeks

https://doi.org/10.3389/fnana.2022.884280

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, all

U6, ITR

CRISPR, sgRNA, Rescue

1E11 vg/animal

IV

2 weeks

https://doi.org/10.1038/s41467-022-30847-x

PHP.eB

POS

Mouse, Pigob/b neonate

CNS, all

U6, ITR

CRISPR, sgRNA, Rescue

1E11 vg/animal

IV

4 months

https://doi.org/10.1038/s41467-022-30847-x

PHP.eB

POS

Mouse, Pigob/− neonate

CNS, all

U6, ITR

CRISPR, sgRNA, Rescue

1E11 vg/animal

IV

4 months

https://doi.org/10.1038/s41467-022-30847-x

PHP.eB

POS

Mouse, Pigob/b neonate

CNS, all

nEF

CRISPR, Cas9

1E11 vg/animal

IV

4 months

https://doi.org/10.1038/s41467-022-30847-x

87115

PHP.eB

POS

Mouse, Pigob/− neonate

CNS, all

nEF

CRISPR, Cas9

1E11 vg/animal

IV

4 months

https://doi.org/10.1038/s41467-022-30847-x

87115

PHP.eB

NEG

Mouse, Lkb1fl/fl

CNS, neurons

hSyn

Recombinase, Cre, FP

RO

https://doi.org/10.1093/genetics/iyac082

PHP.eB

Mouse, Lkb1fl/fl

CNS, neurons

hSyn

FP

RO

https://doi.org/10.1093/genetics/iyac082

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons

Ef1a

FP

4E11 vg/animal

RO

3-4 weeks

https://doi.org/10.7554/eLife.69571

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons

SC1

FP

4E11 vg/animal

RO

3-4 weeks

https://doi.org/10.7554/eLife.69571

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons

SC2

FP

4E11 vg/animal

RO

3-4 weeks

https://doi.org/10.7554/eLife.69571

PHP.eB

POS

Mouse, Slc17a7-Cre

CNS, neurons

Syn FLEX tTA TRE

FP

RO

https://doi.org/10.1038/s41592-022-01468-5

PHP.S

POS

Mouse, Mafb-mCherry-Cre

PNS, cranial sensory gangion

CAG FLEX

Sensor, GCaMP6s

2.9E12 vg/animal

RO

2 weeks

https://doi.org/10.1523/ENEURO.0373-21.2022

100842

PHP.S

POS

Mouse, Penk-Cre

PNS, cranial sensory gangion

CAG FLEX

Sensor, GCaMP6s

2.9E12 vg/animal

RO

https://doi.org/10.1523/ENEURO.0373-21.2022

100842

PHP.S

POS

Mouse, C57BL/6J

PNS, cranial sensory gangion

CAG

FP

1.3E12 vg/animal

RO

2 days

https://doi.org/10.1523/ENEURO.0373-21.2022

37825

PHP.S

POS

Mouse, C57BL/6J

PNS, cranial sensory gangion

CAG

FP

1.3E12 vg/animal

RO

4 days

https://doi.org/10.1523/ENEURO.0373-21.2022

37825

PHP.S

POS

Mouse, C57BL/6J

PNS, cranial sensory gangion

CAG

FP

1.3E12 vg/animal

RO

1 week

https://doi.org/10.1523/ENEURO.0373-21.2022

37825

PHP.S

POS

Mouse, C57BL/6J

PNS, cranial sensory gangion

CAG

FP

1.3E12 vg/animal

RO

2 weeks

https://doi.org/10.1523/ENEURO.0373-21.2022

37825

PHP.S

POS

Mouse, C57BL/6J

PNS, cranial sensory gangion

CAG

FP

1.3E12 vg/animal

RO

3 weeks

https://doi.org/10.1523/ENEURO.0373-21.2022

37825

PHP.S

POS

Mouse, Mafb-mCherry-Cre

PNS, cranial sensory gangion

CAG FLEX

Sensor, GCaMP6s

2.9E12 vg/animal

RO

19 days

https://doi.org/10.1523/ENEURO.0373-21.2022

100842

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

4.9E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41380-022-01580-0

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

MRI reporter, FP

4.9E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41380-022-01580-0

PHP.eB

NEG

Mouse, Fmr1-KO

CNS, neurons

hSyn

Rescue

1E11 vg/animal

RO

4 weeks

https://doi.org/10.15252/emmm.202114649

PHP.eB

NEG

Mouse, Fmr1-KO

CNS, neurons

hSyn

Rescue

1E11 vg/animal

RO

8 weeks

https://doi.org/10.15252/emmm.202114649

PHP.B

POS

Mouse, Tmc1Δ/Δ neonate

Inner ear

CMV

Rescue

3E10 vg/site

utricle injection

4 weeks

https://doi.org/10.3390/biom12070914

PHP.B

POS

Mouse, Tmc1Δ/Δ neonate

Inner ear

CMV

Rescue

6E10 vg/site

utricle injection

4 weeks

https://doi.org/10.3390/biom12070914

PHP.B

POS

Mouse, Tmc1N193I/N193I neonate

Inner ear

CMV

Rescue

3E10 vg/site

utricle injection

4 weeks

https://doi.org/10.3390/biom12070914

PHP.B

POS

Mouse, Tmc1N193I/N193I neonate

Inner ear

CMV

Rescue

6E10 vg/site

utricle injection

4 weeks

https://doi.org/10.3390/biom12070914

PHP.B

POS

Mouse, Tmc1Δ/Δ neonate

Inner ear

CB6

Rescue

3E10 vg/site

utricle injection

4 weeks

https://doi.org/10.3390/biom12070914

PHP.B

NEG

Mouse, Tmc1N193I/N193I neonate

Inner ear

CB6

Rescue

3E9 vg/site

utricle injection

4 weeks

https://doi.org/10.3390/biom12070914

PHP.B

NEG

Mouse, Tmc1N193I/N193I neonate

Inner ear

CB6

Rescue

1.5E10 vg/site

utricle injection

4 weeks

https://doi.org/10.3390/biom12070914

PHP.B

POS

Mouse, Tmc1N193I/N193I neonate

Inner ear

CB6

Rescue

3E10 vg/site

utricle injection

4 weeks

https://doi.org/10.3390/biom12070914

PHP.B

POS

Mouse, Tmc1N193I/N193I neonate

Inner ear

CB6

Rescue

7E10 vg/site

utricle injection

4 weeks

https://doi.org/10.3390/biom12070914

PHP.B

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

1E9 vg/animal

IV

2 weeks

https://doi.org/10.1038/s41590-022-01208-z

PHP.B

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

Rescue

1E9 vg/animal

IV

2 weeks

https://doi.org/10.1038/s41590-022-01208-z

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

CamKIIa

Rescue

1E9 vg/animal

IV

2 weeks

https://doi.org/10.1038/s41590-022-01208-z

PHP.B

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP tTA TRE

Rescue

1E9 vg/animal

IV

2 weeks

https://doi.org/10.1038/s41590-022-01208-z

PHP.B

POS

Mouse, C57BL/6J

CNS, astrocytes

GfaABC1D

FP

1E12 vg/animal

RO

30 days

https://doi.org/10.1186/s13195-022-00999-5

PHP.B

POS

Mouse, C57BL/6J

CNS, astrocytes

GfaABC1D

Rescue

1E11 vg/animal

RO

30 days

https://doi.org/10.1186/s13195-022-00999-5

PHP.B

POS

Mouse, C57BL/6J

CNS, astrocytes

GfaABC1D

Rescue, FP

1E11 vg/animal

RO

30 days

https://doi.org/10.1186/s13195-022-00999-5

CAP-B22

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-021-00969-4

PHP.B

POS

Mouse, Scn1a neonate

CNS, neurons

hSyn1

FP

2E12 vg/animal

Temporal vein

None

https://doi.org/10.1126/sciadv.add2577

PHP.B

POS

Mouse, Scn1a neonate

CNS, neurons

hSyn1

Rescue

2E12 vg/animal

Temporal vein

None

https://doi.org/10.1126/sciadv.add2577

PHP.B

POS

Mouse, DBA/2

CNS, neurons

hSyn1

FP

5E12 vg/animal

Tail vein

None

https://doi.org/10.1126/sciadv.add2577

PHP.B

POS

Mouse, DBA/2

CNS, neurons

hSyn1

Rescue

5E12 vg/animal

Tail vein

None

https://doi.org/10.1126/sciadv.add2577

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

FP

5E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.1126/sciadv.add2577

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

Rescue

5E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.1126/sciadv.add2577

PHP.B

POS

Mouse, tauT205A/A (B6)

CNS, neurons

hSyn1

FP

5E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.1126/sciadv.add2577

PHP.B

POS

Mouse, tauT205A/A (B6)

CNS, neurons

hSyn1

Rescue

5E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.1126/sciadv.add2577

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

FP

1E11 vg/animal

RO

6 weeks

https://doi.org/10.1021/jacs.2c09484

KKPS-PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

FP

1E11 vg/animal

RO

6 weeks

https://doi.org/10.1021/jacs.2c09484

PHP.eB

POS

Mouse, C9orf72+/−;C9-BAC

CNS, all

CMV

Rescue

2.2E13 vg/animal

RO

18-20 months

https://doi.org/10.1093/hmg/ddac271

PHP.eB

POS

Mouse, C9orf72+/−;C9-BAC

CNS, all

CMV

FP

2.2E13 vg/animal

RO

18-20 months

https://doi.org/10.1093/hmg/ddac271

PHP.eB

POS

Mouse, muMt-

CNS, all

CAG

FP

4.5E9 VP/g

Tail vein

7 weeks

https://doi.org/10.1038/s41434-022-00371-0

104061

PHP.eB

POS

Mouse, muMt-

CNS, all

CAG

FP

1.5E9 VP/g

Tail vein

7 weeks

https://doi.org/10.1038/s41434-022-00371-0

104061

PHP.eB

POS

Mouse, muMt-

CNS, all

CAG

FP

3x 1.5E9 VP/g (weekly)

Tail vein

7 weeks

https://doi.org/10.1038/s41434-022-00371-0

104061

PHP.eB

POS

Mouse, LSL-Cas9

CNS, astrocytes

U6, GFAP

CRISPR, sgRNA, Recombinase, Cre

2E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.1172/JCI151803

PHP.eB

POS

Mouse, ICR

CNS, purkinje neurons

L7-6

Rescue, FP

4E12 vg/animal

RO

2 weeks

https://doi.org/10.1242/dev.201214

PHP.eB

POS

Mouse, ICR

CNS, purkinje neurons

L7-6

FP

8E9 vg/animal

RO

2 weeks

https://doi.org/10.1242/dev.201214

PHP.eB

POS

Mouse, Lkb1flox/flox

CNS, neurons

hSyn

Recombinase, Cre

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, Lkb1flox/flox

CNS, neurons

hSyn

FP

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, Lkb1flox/flox

CNS, neurons

hSyn

Rescue

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Rescue

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

FP

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, Hdac4flox/flox

CNS, neurons

hSyn

FP

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, Hdac4flox/flox

CNS, neurons

hSyn

Recombinase, Cre

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, Hdac4flox/flox

CNS, neurons

hSyn tTA TRE

Recombinase, Cre

1E12 vg/animal

RO

18 days

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, Hdac5flox/flox

CNS, neurons

hSyn tTA TRE

Recombinase, Cre

1E12 vg/animal

RO

18 days

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Rescue

1E10 vg/site

Intracranial, thalamus

3 weeks

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

FP

1E10 vg/site

Intracranial, thalamus

3 weeks

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Rescue

1E10 vg/site

Intracranial, hypothalamus

3 weeks

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

FP

1E10 vg/site

Intracranial, hypothalamus

3 weeks

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, Sik3E13∆/+

CNS, neurons

hSyn

Rescue

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, Sik3E13∆/+

CNS, neurons

hSyn

FP

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41586-022-05510-6

PHP.eB

POS

Mouse, Rosa26-Cas9

CNS, all

U6, CMV

CRISPR, sgRNA, Recombinase, Cre

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41586-022-05510-6

60229

PHP.eB

POS

Mouse, C57BL/6J

Retina

H1, CMV

shRNA, FP

1.8E9 vg/site

Intravitreal

10 weeks

https://doi.org/10.1002/acn3.51717

PHP.eB

POS

Mouse, S1PR1flox/flox

CNS, neurons

hSyn1

FP, Recombinase, Cre

1.5E11 vg/animal

Tail vein

8 weeks

https://doi.org/10.1096/fj.202201346R

PHP.eB

POS

Mouse, S1PR1flox/flox

CNS, neurons

hSyn1

FP

1.5E11 vg/animal

Tail vein

8 weeks

https://doi.org/10.1096/fj.202201346R

PHP.eB

POS

Mouse, S1PR1flox/flox

CNS, neurons

hSyn1

FP, Recombinase, Cre

1.5E10 vg/animal

Tail vein

8 weeks

https://doi.org/10.1096/fj.202201346R

PHP.eB

POS

Mouse, S1PR1flox/flox

CNS, neurons

hSyn1

FP

1.5E10 vg/animal

Tail vein

8 weeks

https://doi.org/10.1096/fj.202201346R

PHP.eB

POS

Mouse, S1PR1flox/flox

CNS, neurons

hSyn1

FP, Recombinase, Cre

1.5E9 vg/animal

Tail vein

8 weeks

https://doi.org/10.1096/fj.202201346R

PHP.eB

POS

Mouse, S1PR1flox/flox

CNS, neurons

hSyn1

FP

1.5E9 vg/animal

Tail vein

8 weeks

https://doi.org/10.1096/fj.202201346R

PHP.eB

POS

Mouse, C57BL/6J

Cochlea

CMV

FP

1E10 vg/site

Cochlea PSCC

2 weeks

https://doi.org/10.3390/biom13010038

PHP.S

POS

Mouse, C57BL/6J

Cochlea

CMV

FP

1E10 vg/site

Cochlea PSCC

2 weeks

https://doi.org/10.3390/biom13010038

PHP.eB

POS

Mouse, R6/2

CNS, astrocytes

GfaABC1D

ZFP, FP

1E12 vg/animal

RO

7 weeks

https://doi.org/10.1016/j.celrep.2022.111953

PHP.eB

POS

Mouse, NCAR

CNS, astrocytes

GfaABC1D

ZFP, FP

1E12 vg/animal

RO

7 weeks

https://doi.org/10.1016/j.celrep.2022.111953

PHP.eB

POS

Mouse, R6/2

CNS, neurons

hSyn1

ZFP, FP

1E12 vg/animal

RO

7 weeks

https://doi.org/10.1016/j.celrep.2022.111953

PHP.eB

POS

Mouse, NCAR

CNS, neurons

hSyn1

ZFP, FP

1E12 vg/animal

RO

7 weeks

https://doi.org/10.1016/j.celrep.2022.111953

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP, U6

CRISPR, Cas13X, sgRNA

1.5E9 vg/site

Intracranial, striatum

4 weeks

https://doi.org/10.1038/s41434-023-00382-5

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

1E9 vg/site

Intracranial, striatum

4 weeks

https://doi.org/10.1038/s41434-023-00382-5

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP, U6

CRISPR, Cas13X

1.5E9 vg/site

Intracranial, striatum

8 weeks

https://doi.org/10.1038/s41434-023-00382-5

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP, U6

CRISPR, Cas13X, sgRNA

1.5E9 vg/site

Intracranial, striatum

8 weeks

https://doi.org/10.1038/s41434-023-00382-5

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

1E9 vg/site

Intracranial, striatum

8 weeks

https://doi.org/10.1038/s41434-023-00382-5

PHP.eB

NEG

Mouse, LSLRfxCas13dfl/fl

CNS, neurons

hSyn, U6

CRISPR, crRNA, Recombinase, Cre

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1186/s13059-023-02860-w

PHP.eB

POS

Mouse, Sik3-E5fl/fl

CNS, neurons

hSyn

Recombinase, Cre

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1186/s13059-023-02860-w

PHP.eB

NEG

Mouse, LSLRfxCas13d+/flAi14+/fl

CNS, neurons

hSyn, U6

CRISPR, crRNA, Recombinase, Cre

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1186/s13059-023-02860-w

PHP.eB

POS

Mouse, Ai14

CNS, neurons

hSyn, U6

CRISPR, crRNA, Recombinase, Cre

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1186/s13059-023-02860-w

PHP.eB

POS

Mouse, FVB.129P2-Pde6b+ tyrc-ch Fmr1tm1Cgr/J

CNS, neurons

hSyn

Rescue

2E10 vg/g

Tail vein

4 weeks

https://doi.org/10.3390/genes14020505

PHP.eB

POS

Mouse, Syvn1/Hrd1loxP/loxP

CNS, neurons

hSyn

FP, Recombinase, Cre

IV

3 weeks

https://doi.org/10.1016/j.celrep.2023.112267

105540

PHP.eB

POS

Mouse, S1PR1flox/flox

Retina, optic nerve

hSyn1

Recombinase, Cre

1.5E11 vg/animal

Tail vein

1 week

10.4103/1673-5374.344952

PHP.eB

POS

Mouse, S1PR1flox/flox

Retina, optic nerve

hSyn1

FP

1.5E11 vg/animal

Tail vein

1 week

10.4103/1673-5374.344952

PHP.eB

POS

Mouse, Oprm1Cre/Cre

CNS, Oprm1+ neurons

CAG FLEX

FP

1.5E9 vg/animal

RO

4 weeks

10.1097/j.pain.0000000000002751

28306

PHP.eB

POS

Mouse, C57BL/6N

CNS, neurons

hSyn1

Rescue

5E10 vg/animal

RO

2 weeks

https://doi.org/10.1371/journal.pbio.3001813

PHP.eB

POS

Mouse, C57BL/6N

CNS, neurons

hSyn1

FP

5E10 vg/animal

RO

2 weeks

https://doi.org/10.1371/journal.pbio.3001813

PHP.eB

POS

Mouse, C57BL/6N

CNS, excitatory neurons

Camk2a

Rescue

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1371/journal.pbio.3001813

PHP.eB

POS

Mouse, C57BL/6N

CNS, excitatory neurons

Camk2b

Rescue

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1371/journal.pbio.3001813

PHP.eB

POS

Mouse, Vglut2-Cre

CNS, excitatory glutamatergic neurons

hSyn DIO

Rescue

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1371/journal.pbio.3001813

PHP.eB

POS

Mouse, C57BL/6N

CNS, neurons

hSyn1

Rescue

2.5E10 vg/animal

RO

2 weeks

https://doi.org/10.1371/journal.pbio.3001813

PHP.eB

POS

Mouse, C57BL/6N

CNS, neurons

hSyn1

Rescue

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1371/journal.pbio.3001813

PHP.B

POS

Mouse, H11Cas9 SOD1G93A neonate

CNS, all

U6, CBA

CRISPR, sgRNA, FP

2E11 vg/site

ICV

5 weeks

https://doi.org/10.1038/s41434-022-00375-w

PHP.eB

POS

Mouse, H11Cas9 SOD1G93A

U6, CAG

CRISPR, sgRNA, FP

1E12 vg/animal

IT

10 weeks

https://doi.org/10.1038/s41434-022-00375-w

PHP.eB

POS

Mouse, H11Cas9 SOD1G93A

U6, CAG

CRISPR, sgRNA, FP

1E12 vg/animal

IV

https://doi.org/10.1038/s41434-022-00375-w

PHP.eB

POS

Mouse

CNS, astrocytes

GfaABC1D

FP

RO

6 weeks

https://chimia.ch/chimia/article/view/2022_1033/2022_1033

CAP-B10

POS

Mouse, C57BL/6J

CNS, all

CBh

HA-FXN

1.9E9 vg/g

RO

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

CAP-B22

POS

Mouse, C57BL/6J

CNS, all

CBh

HA-FXN

1.9E9 vg/g

RO

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

PHP.C2

POS

Mouse, C57BL/6J

CNS, all

CBh

HA-FXN

1.9E9 vg/g

RO

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

CAP-B10

NEG

Mouse, BALB/cJ

CNS, all

CBh

HA-FXN

1.9E9 vg/g

RO

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

CAP-B22

NEG

Mouse, BALB/cJ

CNS, all

CBh

HA-FXN

1.9E9 vg/g

RO

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

PHP.C2

POS

Mouse, BALB/cJ

CNS, all

CBh

HA-FXN

1.9E9 vg/g

RO

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

CAP-B10

NEG

Mouse, C57BL/6J

Liver

CBh

HA-FXN

1.9E9 vg/g

RO

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

CAP-B22

NEG

Mouse, C57BL/6J

Liver

CBh

HA-FXN

1.9E9 vg/g

RO

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

PHP.C2

NEG

Mouse, C57BL/6J

Liver

CBh

HA-FXN

1.9E9 vg/g

RO

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

CAP-B10

NEG

Mouse, BALB/cJ

Liver

CBh

HA-FXN

1.9E9 vg/g

RO

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

CAP-B22

NEG

Mouse, BALB/cJ

Liver

CBh

HA-FXN

1.9E9 vg/g

RO

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

PHP.C2

NEG

Mouse, BALB/cJ

Liver

CBh

HA-FXN

1.9E9 vg/g

RO

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

CAP-B10

NEG

NHP, cynologous macaque

CNS, all

CBh

HA-FXN

1.9E9 vg/g

IV

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

CAP-B22

NEG

NHP, cynologous macaque

CNS, all

CBh

HA-FXN

1.9E9 vg/g

IV

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

PHP.C2

NEG

NHP, cynologous macaque

CNS, all

CBh

HA-FXN

1.9E9 vg/g

IV

4 weeks

https://doi.org/10.1016/j.medj.2022.11.002

PHP.S

POS

Rat, Wistar neonate

PNS, all

CAG

FP

2.1E11 vg/animal

Intraperitoneal, IP

5 weeks

https://doi.org/10.3389/fnins.2023.1001007

59462

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41587-022-01648-w

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

Barcode

5E10 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41587-022-01648-w

CAP-B10

POS

Mouse, C57BL/6J

CNS, all

CAG

Barcode

5E10 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41587-022-01648-w

PHP.N

POS

Mouse, C57BL/6J

CNS, all

CAG

Barcode

5E10 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41587-022-01648-w

PHP.AX

POS

Mouse, C57BL/6J

CNS, all

CAG

Barcode

5E10 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41587-022-01648-w

PHP.V1

POS

Mouse, C57BL/6J

CNS, all

CAG

Barcode

5E10 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41587-022-01648-w

PHP.B8

POS

Mouse, C57BL/6J

CNS, all

CAG

Barcode

5E10 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41587-022-01648-w

CAP-Mac

POS

NHP, rhesus macaque infant

CNS, all

CAG

FP

5E13 vg/kg

IV, saphenous vein

11 weeks

https://doi.org/10.1038/s41587-022-01648-w

PHP.AX

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41587-022-01648-w

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

1.5E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41587-022-01648-w

PHP.AX

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

1.5E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41587-022-01648-w

PHP.AX

POS

Mouse, DBA/2J

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41587-022-01648-w

PHP.AX

POS

Mouse, FVB

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41587-022-01648-w

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1126/sciadv.adg6618

PHP.eB

POS

Mouse, Car4-KO

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1126/sciadv.adg6618

PHP.C2

POS

Mouse, NOD/ShiLtJ

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1126/sciadv.adg6618

PHP.eC

POS

Mouse, NOD/ShiLtJ

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1126/sciadv.adg6618

PHP.C2

POS

Mouse, BALB/cJ

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1126/sciadv.adg6618

PHP.eC

POS

Mouse, BALB/cJ

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1126/sciadv.adg6618

PHP.eB

NEG

Mouse, CBA/J

CNS, all

CAG

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1126/sciadv.adg6618

PHP.N

POS

Mouse, CBA/J

CNS, all

CAG

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1126/sciadv.adg6618

PHP.eC

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1126/sciadv.adg6618

PHP.eB

POS

Rat, Shaker

CNS, purkinje neurons

L7-6

Rescue, FP

2E12 vg/animal

ICV

13 weeks

https://doi.org/10.1093/hmg/ddad004

PHP.eB

NEG

Rat, Shaker

CNS, purkinje neurons

L7-6

FP

1E12 vg/animal

ICV

https://doi.org/10.1093/hmg/ddad004

PHP.eB

POS

Rat, Shaker

CNS, purkinje neurons

L7-6

FP

2E12 vg/animal

ICV

https://doi.org/10.1093/hmg/ddad004

PHP.eB

POS

Rat, Shaker

CNS, purkinje neurons

L7-6

FP

4E12 vg/animal

ICV

https://doi.org/10.1093/hmg/ddad004

AAV9-X1

POS

Mouse, C57BL/6J

CNS, CNS, endothelial

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

PHP.V1

POS

Mouse, C57BL/6J

CNS, astrocytes endothelial

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

Mouse, C57BL/6J

CNS, endothelial

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

Mouse, BALB/cJ

CNS, endothelial

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

Mouse, FVB

CNS, endothelial

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

Mouse, CBA/J

CNS, endothelial

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

Rat, Wistar Hooded

CNS, endothelial

CAG

FP

3E13 vg/kg

Tail vein

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV1-X1

POS

Mouse, C57BL/6J

CNS, endothelial

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV1-X1

POS

Mouse, CBA/J

CNS, endothelial

CAG

Rescue

RO

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV1-PHP.B

NEG

Mouse, C57BL/6J

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

Mouse, C57BL/6J aged

CNS, endothelial

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

Mouse, C57BL/6J

CNS, endothelial

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

Mouse, Pdgfb ret/ret

CNS, endothelial

CAG

FP

3E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

Mouse, Pdgfb ret/+

CNS, endothelial

CAG

FP

3E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

Mouse, Pdgfb ret/ret

CNS, endothelial

CAG

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

Mouse, Pdgfb ret/+

CNS, endothelial

CAG

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-DJ-X1

POS

Mouse, C57BL/6J

CNS, endothelial

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

NEG

NHP, marmoset

CNS, all

CAG

FP

3.5E13 vg/kg

IV, saphenous vein

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

Mouse, Hevin-KO

CNS, endothelial

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

Mouse, Hevin-KO

CNS, endothelial

CAG

Rescue

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-023-38582-7

PHP.eB

NEG

NHP, macaca nemestrina, brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

PHP.V1

NEG

NHP, macaca nemestrina, brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

CAP-B10

NEG

NHP, macaca nemestrina, brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

CAP-B22

NHP, macaca nemestrina, brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

CAP-Mac

NEG

NHP, macaca nemestrina, brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

MaCPNS2

POS

NHP, macaca nemestrina, brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

NHP, macaca nemestrina, brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

NHP, rhesus macaque brain slice culture

CNS, all

CAG

FP

2.5E10 vg

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

PHP.eB

NEG

NHP, rhesus macaque brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

PHP.V1

NEG

NHP, rhesus macaque brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

CAP-B10

NEG

NHP, rhesus macaque brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

CAP-B22

NHP, rhesus macaque brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

CAP-Mac

NEG

NHP, rhesus macaque brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

MaCPNS2

NHP, rhesus macaque brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

NHP, rhesus macaque brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

NHP, macaca nemestrina, brain slice culture

CNS, all

CAG

Rescue

2.5E10 vg

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

PHP.eB

NEG

Human, cortical brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

PHP.V1

NEG

Human, cortical brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

CAP-B10

NEG

Human, cortical brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

CAP-B22

Human, cortical brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

CAP-Mac

NEG

Human, cortical brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

MaCPNS2

NEG

Human, cortical brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

Human, cortical brain slice culture

CNS, all

CAG

Rescue

2E9 vg (pool)

Direct application to tissue

7-10 days

https://doi.org/10.1038/s41467-023-38582-7

AAV-X1.1

POS

NHP, rhesus macaque infant

CNS, neurons

CAG

FP

2.5E13 vg/kg

IV, saphenous vein

4 weeks

https://doi.org/10.1038/s41467-023-38582-7

PHP.eB

NEG

NHP, rhesus macaque infant

CNS, all

CAG

Rescue

1.25E13 vg/kg (pool)

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-B10

NEG

NHP, rhesus macaque infant

CNS, all

CAG

Rescue

1.25E13 vg/kg (pool)

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-B22

NEG

NHP, rhesus macaque infant

CNS, all

CAG

Rescue

1.25E13 vg/kg (pool)

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

NHP, rhesus macaque infant

CNS, all

CAG

Rescue

1.25E13 vg/kg (pool)

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-C2

POS

NHP, rhesus macaque infant

CNS, all

CAG

Rescue

1.25E13 vg/kg (pool)

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

AAV9.452sub.LUNG1

NHP, rhesus macaque infant

CNS, all

CAG

Rescue

1.25E13 vg/kg (pool)

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

NHP, rhesus macaque infant

CNS, neurons

CAG

FP

5E13 vg/kg

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

NHP, green monkey

CNS, neurons

CAG

FP

7.5E13 vg/kg

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

NHP, rhesus macaque infant

CNS, neurons

CAG

FP

2.5E13 vg/kg

ICM

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

PHP.eB

NEG

NHP, rhesus macaque infant

CNS, all

CAG

Rescue

3.1E12 vg/kg (pool)

ICM

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-B10

NEG

NHP, rhesus macaque infant

CNS, all

CAG

Rescue

3.1E12 vg/kg (pool)

ICM

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-B22

NEG

NHP, rhesus macaque infant

CNS, all

CAG

Rescue

3.1E12 vg/kg (pool)

ICM

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

AAV9.452sub.LUNG1

POS

NHP, rhesus macaque infant

CNS, all

CAG

Rescue

3.1E12 vg/kg (pool)

ICM

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

NHP, rhesus macaque infant

CNS, all

CAG

Rescue

3.1E12 vg/kg (pool)

ICM

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-C2

NEG

NHP, rhesus macaque infant

CNS, all

CAG

Rescue

3.1E12 vg/kg (pool)

ICM

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

NEG

NHP, rhesus macaque infant

CNS, all

CAG

Sensor, GCaMP7s

2.5E13 vg/kg

ICM

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

NHP, rhesus macaque infant

CNS, all

CAG

Sensor, GCaMP8s

3E13 vg/kg

IV, saphenous vein

4-6 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1.5E11 vg/animal

ICV

3 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

Mouse, BALB/cJ

CNS, all

CAG

FP

1.5E11 vg/animal

ICV

3 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

Mouse, DBA/2J

CNS, all

CAG

FP

1.5E11 vg/animal

ICV

3 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

Mouse, C57BL/6J neonate

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

Mouse, BALB/cJ

CNS, all

CAG

FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

Mouse, DBA/2J

CNS, all

CAG

FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

Mouse, C57BL/6J

CNS, all

CAG

Sensor, GCaMP6f

5E10 vg/animal

ICV

3 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

Mouse, C57BL/6J

CNS, all

CAG tTA-TRE

Sensor, GCaMP6f

5E10 vg/animal

ICV

3 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

Human, iPSC neuron culture

CNS, neurons

CAG

FP

1E1-1E5 vg/cell

Direct application to culture

4 days

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

NHP, rhesus macaque brain slice culture

CNS, all

CAG

Rescue

1E11 vg/slice

Direct application to tissue

8 days

https://doi.org/10.1038/s41565-023-01419-x

PHP.eB

NEG

NHP, rhesus macaque adult

CNS, neurons

CAG

Rescue

9.4E12 vg/kg (pool)

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-B10

NEG

NHP, rhesus macaque adult

CNS, neurons

CAG

Rescue

9.4E12 vg/kg (pool)

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-B22

NEG

NHP, rhesus macaque adult

CNS, neurons

CAG

Rescue

9.4E12 vg/kg (pool)

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

AAV9.452sub.LUNG1

NEG

NHP, rhesus macaque adult

CNS, neurons

CAG

Rescue

9.4E12 vg/kg (pool)

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

NHP, rhesus macaque adult

CNS, neurons

CAG

Rescue

9.4E12 vg/kg (pool)

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-C2

NEG

NHP, rhesus macaque adult

CNS, neurons

CAG

Rescue

9.4E12 vg/kg (pool)

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

NHP, rhesus macaque adult

CNS, neurons

CAG

FP

1E13 vg/kg

IV, saphenous vein

4-11 weeks

https://doi.org/10.1038/s41565-023-01419-x

CAP-Mac

POS

NHP, marmoset

CNS, endothelial

CAG

FP

1E13 vg/kg

IV, saphenous vein

31 days

https://doi.org/10.1038/s41565-023-01419-x

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CMV

FP

1E12 vg/animal

Tail vein

14-21 days

https://doi.org/10.1128/jvi.00174-23

PHP.eB

POS

Mouse, Ube3a deletion

CNS, all

pCBA, pGK

Rescue, FP

1E12 vg/animal

Tail vein

3-6 weeks

https://doi.org/10.1016/j.ymthe.2023.01.013

PHP.eB

POS

Mouse, Ube3a deletion

CNS, all

CMV

FP

1E12 vg/animal

Tail vein

3-6 weeks

https://doi.org/10.1016/j.ymthe.2023.01.013

PHP.B

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

Rescue

1E9 vg/animal

Tail vein

2 months

https://doi.org/10.15252/emmm.202216805

PHP.B

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

1E9 vg/animal

Tail vein

2 months

https://doi.org/10.15252/emmm.202216805

PHP.B

POS

Mouse, C57BL/6J aged

CNS, astrocytes

GFAP

Rescue

1E9 vg/animal

Tail vein

2 months

https://doi.org/10.15252/emmm.202216805

PHP.B

POS

Mouse, C57BL/6J aged

CNS, astrocytes

GFAP

FP

1E9 vg/animal

Tail vein

2 months

https://doi.org/10.15252/emmm.202216805

PHP.B

POS

Mouse, APP/PS1

CNS, astrocytes

GFAP

Rescue

1E9 vg/animal

Tail vein

8 months

https://doi.org/10.15252/emmm.202216805

PHP.B

POS

Mouse, APP/PS1

CNS, astrocytes

GFAP

FP

1E9 vg/animal

Tail vein

8 months

https://doi.org/10.15252/emmm.202216805

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Sensor, GCaMP7s

4E11 vg/animal

RO

5-34 weeks

https://doi.org/10.3389/fnins.2023.1181828

PHP.eB

POS

Mouse, SELECTIV-KO-Myh6

Heart

CAG

FP

2E11 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-023-01896-x

PHP.eB

NEG

Mouse, LSL-AAVR-mCh+/-Myh6-Cre-/-AAVR+/-

Heart

CAG

FP

2E11 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-023-01896-x

PHP.eB

POS

Mouse, SELECTIV-KO-Myh6

CNS, all

CAG

FP

2E11 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-023-01896-x

PHP.eB

POS

Mouse, LSL-AAVR-mCh+/-Myh6-Cre-/-AAVR+/-

CNS, all

CAG

FP

2E11 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-023-01896-x

PHP.eB

POS

Mouse, Del(3.0Mb) hetero

CNS, neurons

hSyn

FP

5E9 vg/animal

RO

7 days

https://doi.org/10.3390/biom13050763

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

FP

5E9 vg/animal

RO

7 days

https://doi.org/10.3390/biom13050763

PHP.S

POS

Mouse

PNS, knee joint afferents

CAG

Rescue, FP

1.5E11 vg/animal

Intraarticular

4 days

https://doi.org/10.1038/s41467-023-37602-w

PHP.S

POS

Mouse

PNS, knee joint afferents

CAG

FP

1.5E11 vg/animal

Intraarticular

4 days

https://doi.org/10.1038/s41467-023-37602-w

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Sensor, SpikeyGi-Kv2.1

6E11 vg/site

Intracranial, cortex

2-3 weeks

https://doi.org/10.1038/s41592-023-01820-3

PHP.eB

POS

Mouse, GFAP-Cre-PERK-fl/fl

CNS, astrocytes

CAG FLEX

FP

5E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1002/jnr.25224

28306

PHP.eB

POS

Mouse, ST3GAL5-KO-B4GALNT1-KO neonate

CNS, all

hSyn1, miR122BS

Rescue

3E11 vg/animal

Facial vein

2 weeks - 1 year

https://doi.org/10.1172/jci.insight.168688

PHP.eB

POS

Mouse, ST3GAL5-KO-B4GALNT1-KO neonate

CNS, all

hSyn1, miR122BS

FP

3E11 vg/animal

Facial vein

2 weeks - 1 year

https://doi.org/10.1172/jci.insight.168688

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

U6, Cbh

CRISPR, v1em PE3

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41587-023-01758-z

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

U6, Cbh

CRISPR, v3em PE3

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41587-023-01758-z

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

U6, Cbh

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41587-023-01758-z

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

Rescue

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1096/fj.202300149R

PHP.eB

NEG

NHP, macaca fascicularis

CNS, neurons

hSyn

FP

5E13 vg/animal

IV, saphenous vein

4 weeks

https://doi.org/10.1126/sciadv.adf4888

PHP.eB

POS

Mouse, Aldh1/1-Cre

CNS, hippocampal astrocytes

hGfaABC1D DIO

Rescue

6E9 vg/site

Intracranial, hippocampus

3-6 months

https://doi.org/10.1126/sciadv.ade1282

PHP.eB

POS

Mouse, Aldh1/1-Cre

CNS, astrocytes

hGfaABC1D DIO

Chemogenetic, hM4Di, FP

1.5E9 vg/site

Intracranial, hippocampus

https://doi.org/10.1126/sciadv.ade1282

PHP.eB

POS

Mouse, NTG

CNS, astrocytes

hGfaABC1D DIO

Chemogenetic, hM4Di, FP

1.5E9 vg/site

Intracranial, hippocampus

https://doi.org/10.1126/sciadv.ade1282

PHP.eB

POS

Mouse, Aldh1/1-Cre-Cxcr3-KO

CNS, hippocampal astrocytes

hGfaABC1D DIO

Rescue

6E9 vg/site

Intracranial, hippocampus

3 months

https://doi.org/10.1126/sciadv.ade1282

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

CAG

FP

RO

https://doi.org/10.1126/scitranslmed.abq1019

PHP.B

NEG

Mouse, B6129F1-loxP-3xStop-loxP-tdTomato, Pax6Sey/+

Retina

CBA

Recombinase, Cre

5E11 vg/animal

Tail vein

up to 70 days

https://doi.org/10.1038/s41434-023-00400-6

PHP.B

NEG

Mouse, B6129F1-loxP-3xStop-loxP-tdTomato, Pax6Sey/+

Retina

CBA

Recombinase, Cre

1.5E11 vg/animal

Tail vein

up to 70 days

https://doi.org/10.1038/s41434-023-00400-6

PHP.B

NEG

Mouse, B6129F1-loxP-3xStop-loxP-tdTomato, Pax6Sey/+

Retina

CBA

Recombinase, Cre

7.5E10 vg/animal

Tail vein

up to 70 days

https://doi.org/10.1038/s41434-023-00400-6

PHP.B

NEG

Mouse, B6129F1-loxP-3xStop-loxP-tdTomato, Pax6Sey/+

Retina

CBA

Recombinase, Cre

2E10 vg/animal

Tail vein

up to 70 days

https://doi.org/10.1038/s41434-023-00400-6

PHP.B

NEG

Mouse, B6129F1-loxP-3xStop-loxP-tdTomato, Pax6Sey/+

Retina

CBA

Recombinase, Cre

1.5E10 vg/animal

Tail vein

up to 70 days

https://doi.org/10.1038/s41434-023-00400-6

PHP.B

POS

Mouse, B6129F1-loxP-3xStop-loxP-tdTomato, Pax6Sey/+

CNS, all

CBA

Recombinase, Cre

8.4E10 vg/animal

Intravitreal

17-30 days

https://doi.org/10.1038/s41434-023-00400-6

PHP.B

POS

Mouse, B6129F1-loxP-3xStop-loxP-tdTomato, Pax6Sey/+

CNS, all

CBA

Recombinase, Cre

8.4E10 vg/animal

Intrastromal

16-30 days

https://doi.org/10.1038/s41434-023-00400-6

PHP.B

POS

Mouse, B6129F1-loxP-3xStop-loxP-tdTomato, Pax6Sey/+

Cornea/Retina

CBA

Recombinase, Cre

8.4E10 vg/animal

Intravitreal

17-30 days

https://doi.org/10.1038/s41434-023-00400-6

PHP.B

POS

Mouse, B6129F1-loxP-3xStop-loxP-tdTomato, Pax6Sey/+

Cornea/Retina

CBA

Recombinase, Cre

8.4E10 vg/animal

Intrastromal

16-30 days

https://doi.org/10.1038/s41434-023-00400-6

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

U6

STARmap+

2E12 vg/animal

RO

30 days (2nd injection at day 7)

https://doi.org/10.1038/s41586-023-06569-5

PHP.eB

POS

Mouse, Thy1-EYFP

CNS, all

U6

STARmap+

1.7E12 vg/animal

RO

5 weeks

https://doi.org/10.1038/s41586-023-06569-5

PHP.eB

POS

Mouse, Thy1-EYFP hippocampal slice culture

CNS, astrocytes

GFAP

Sensor, C2

6.7E10 vg/sample

Direct application to tissue

9 days

https://doi.org/10.1186/s11658-023-00472-7

PHP.eB

POS

Mouse, Thy1-EYFP neonate

CNS, astrocytes

GFAP

Sensor, C2

1E11 vg/animal

Facial vein

2 weeks

https://doi.org/10.1186/s11658-023-00472-7

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1371/journal.pbio.3002112

PHP.eB

NEG

Mouse, BALB/cJ

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1371/journal.pbio.3002112

PHP.eB

POS

Mouse, Slc6a4-Cre

CNS, serotonergic neurons

CMV FLEX, U6

CRISPR, SaCas9, sgRNA

8E9 vg/site

Intracranial, dorsal raphe

4 weeks

https://doi.org/10.1038/s12276-023-01052-7

PHP.eB

POS

Mouse, Slc6a4-Cre

CNS, serotonergic neurons

hSyn DIO

Sensor, GCaMP7s

8E9 vg/site

Intracranial, dorsal raphe

2 weeks

https://doi.org/10.1038/s12276-023-01052-7

PHP.eB

POS

Mouse, Slc6a4-Cre

CNS, serotonergic neurons

CAG

Sensor, iSeroSnFR-Nlgn

8E9 vg/site

Intracranial, dorsal raphe

2 weeks

https://doi.org/10.1038/s12276-023-01052-7

PHP.eB

POS

Mouse, Slc6a4-Cre

CNS, serotonergic neurons

Ef1a DIO

Opsin, ChR2(C128S/D157A)

8E9 vg/site

Intracranial, dorsal raphe

https://doi.org/10.1038/s12276-023-01052-7

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

7E10 vg/animal

RO

5-20 weeks

https://doi.org/10.1161/ATVBAHA.122.318658

59462

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

Rescue

7E10 vg/animal

RO

5-20 weeks

https://doi.org/10.1161/ATVBAHA.122.318658

59462

PHP.eB

POS

Mouse, Rosa26-Cas9 neonate

CNS, neurons

hSyn1, U6

CRISPR, sgRNA, FP

1E11 vg/animal

ICV

8 weeks

https://doi.org/10.3389/fcell.2023.1227723

PHP.eB

POS

Mouse, loxSOD1G37R neonate

CNS, all

CAG

Rescue

1.4E10 vg/animal

intrathecal

200 days

https://doi.org/10.1093/brain/awad222

PHP.eB

POS

Mouse, loxSOD1G37R neonate

CNS, all

CAG

FP

1.4E10 vg/animal

intrathecal

200 days

https://doi.org/10.1093/brain/awad222

PHP.eB

POS

Mouse, APP/PS1

CNS, astrocytes

GFAP

shRNA, FP

ICV

https://doi.org/10.14336/AD.2023.1006

PHP.eB

POS

Mouse, hThy1-asyn

CNS

FP

1.6E11 vg/animal

Tail vein

3 months

https://doi.org/10.3390/biomedicines11102863

PHP.eB

POS

Mouse, hThy1-asyn

CNS

Rescue

1.6E11 vg/animal

Tail vein

3 months

https://doi.org/10.3390/biomedicines11102863

PHP.eB

POS

Mouse, hTau

CNS

FP

1.6E11 vg/animal

Tail vein

3 months

https://doi.org/10.3390/biomedicines11102863

PHP.eB

POS

Mouse, hTau

CNS

Rescue

1.6E11 vg/animal

Tail vein

3 months

https://doi.org/10.3390/biomedicines11102863

PHP.eB

POS

Mouse, APP/PS1

CNS

FP

1.6E11 vg/animal

Tail vein

3 months

https://doi.org/10.3390/biomedicines11102863

PHP.eB

POS

Mouse, APP/PS1

CNS

Rescue

1.6E11 vg/animal

Tail vein

3 months

https://doi.org/10.3390/biomedicines11102863

PHP.eB

POS

Mouse, hThy1-asyn

CNS

FP

1.1E12 vg/animal

Tail vein

2 weeks

https://doi.org/10.3390/biomedicines11102863

PHP.eB

POS

Mouse, C57BL/6J

CNS, mu-OR cells

mMORp

FP

4.3E11 vg/animal

RO

6 weeks

https://doi.org/10.1038/s41467-023-41407-2

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG mu-OR cells

mMORp

FP

5.6E10 vg/animal

ICV

6 weeks

https://doi.org/10.1038/s41467-023-41407-2

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG all

CAG

FP

8.4E10 vg/animal

ICV

6 weeks

https://doi.org/10.1038/s41467-023-41407-2

59462

PHP.S

POS

Mouse, Tac1-Cre

PNS, DRG, ENS Tac1+ neurons

Flex

Rescue, FP

1E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41586-023-06607-2

PHP.eB

POS

Mouse, HD KI-140Q

CNS

Rescue

1E10 vg/site

Intracranial, striatum

1 month

https://doi.org/10.1002/advs.202301120

PHP.eB

POS

Mouse, HD KI-140Q

CNS

FP

1E10 vg/site

Intracranial, striatum

1 month

https://doi.org/10.1002/advs.202301120

PHP.eB

POS

Mouse, HD KI-140Q

CNS

Rescue

5E11 vg/animal

RO

1 month

https://doi.org/10.1002/advs.202301120

PHP.eB

POS

Mouse, HD KI-140Q

CNS

FP

5E11 vg/animal

RO

1 month

https://doi.org/10.1002/advs.202301120

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

Rescue, FP

2-4E8 vg/site

Intracranial, SNc

3 weeks

https://doi.org/10.1038/s42255-023-00887-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

2-4E8 vg/site

Intracranial, SNc

3 weeks

https://doi.org/10.1038/s42255-023-00887-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

Rescue, FP

2-4E8 vg/site

Intracranial, striatum

3 weeks

https://doi.org/10.1038/s42255-023-00887-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

2-4E8 vg/site

Intracranial, striatum

3 weeks

https://doi.org/10.1038/s42255-023-00887-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

Rescue, FP

2-4E8 vg/site

Intracranial, cortex

3 weeks

https://doi.org/10.1038/s42255-023-00887-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

2-4E8 vg/site

Intracranial, cortex

3 weeks

https://doi.org/10.1038/s42255-023-00887-8

PHP.eB

POS

Mouse, 5xFAD

CNS, astrocytes

GFAP

Rescue, FP

2-4E11 vg/animal

RO

3 months

https://doi.org/10.1038/s42255-023-00887-8

PHP.eB

POS

Mouse, 5xFAD

CNS, astrocytes

GFAP

FP

2-4E11 vg/animal

RO

3 months

https://doi.org/10.1038/s42255-023-00887-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG, U6

shRNA, FP

Intracranial, cortex

3 weeks

https://doi.org/10.1016/j.jare.2022.11.007

PHP.S

POS

Mouse, Atg f/f neonate

PNS, DRG

hSyn1

FP

1E12 vg/animal

Facial vein

2 months

https://doi.org/10.1080/15548627.2023.2244861

PHP.S

POS

Mouse, Atg f/f neonate

PNS, DRG

hSyn1

Recombinase, Cre

1E12 vg/animal

Facial vein

2 months

https://doi.org/10.1080/15548627.2023.2244861

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

Sensor, GCaMP6s

Tail vein

1-2 months

https://doi.org/10.1038/s41598-023-40321-3

PHP.eB

POS

Mouse, Ai203

CNS, excitatory neurons

TRE

Opsin, ChroME, FP

Intracranial

https://doi.org/10.1016/j.celrep.2023.112909

PHP.S

POS

Mouse, Piezo2fl/fl;Ai9fl/+

PNS, DRG neurons

CAG

Recombinase, Cre

7E10 vg/animal

Intrathecal, lumbar

4 weeks

https://doi.org/10.1016/j.cell.2023.07.006

51904

PHP.S

POS

Mouse, Piezo2fl/fl

PNS, DRG

CAG

FP

7E10 vg/animal

intrathecal

4 weeks

https://doi.org/10.1016/j.cell.2023.07.006

59462

PHP.S

POS

Mouse, Piezo2fl/fl

PNS, DRG neurons

CAG

Recombinase, Cre

7E10 vg/animal

intrathecal

4 weeks

https://doi.org/10.1016/j.cell.2023.07.006

51904

PHP.S

POS

Mouse, Phox2bCre+/−;Piezo2fl/fl

PNS, DRG neurons

CAG

Recombinase, Cre

7E10 vg/animal

intrathecal

4 weeks

https://doi.org/10.1016/j.cell.2023.07.006

51904

PHP.S

POS

Mouse, Hoxb8Cre+/−;Piezo2 fl/fl

PNS, DRG neurons

CAG

Recombinase, Cre

7E10 vg/animal

intrathecal

4 weeks

https://doi.org/10.1016/j.cell.2023.07.006

51904

PHP.S

POS

Mouse, Vil1Cre+/−;Piezo2fl/fl

PNS, DRG neurons

CAG

Recombinase, Cre

7E10 vg/animal

intrathecal

4 weeks

https://doi.org/10.1016/j.cell.2023.07.006

51904

PHP.S

POS

Mouse, Piezo2fl/fl;Ai9fl/+

PNS, DRG neurons

CAG

Recombinase, Cre

7E10 vg/animal

intrathecal

4 weeks

https://doi.org/10.1016/j.cell.2023.07.006

51904

PHP.eB

POS

Mouse, Thy1-EGFP neonate hippocampal organotypic slice

CNS, astrocytes

GFAP

Sensor, C2-SNAP

6.7E10 vg/slice

Direct application to culture

9 days

https://doi.org/10.1186/s11658-023-00472-7

PHP.eB

POS

Mouse, Thy1-EGFP neonate hippocampal organotypic slice

CNS, astrocytes

GFAP

Sensor, C2m2-SNAP

6.7E10 vg/slice

Direct application to culture

9 days

https://doi.org/10.1186/s11658-023-00472-7

PHP.eB

POS

Mouse, Thy1-EGFP neonate

CNS, hippocampus astrocytes

GFAP

Sensor, C2-SNAP

1E11 vg/animal

Facial vein

2 weeks

https://doi.org/10.1186/s11658-023-00472-7

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Proximity Label, APEX2

2E11 vg/animal

RO

https://doi.org/10.7554/eLife.86972.2

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Rescue

1E11 vg/animal

RO

https://doi.org/10.7554/eLife.86972.2

PHP.eB

POS

Mouse, Slc6a17iCre/Cas9+

CNS, neurons

hSyn DIO, U6

Rescue, CRISPR, sgRNA

1E11 vg/animal

RO

https://doi.org/10.7554/eLife.86972.2

PHP.eB

POS

Mouse, Cpt1alox/lox

CNS, astrocytes

GFAP

Recombinase, Cre, FP

1E11 vg/animal

RO

4 weeks

https://doi.org/10.1038/s42255-023-00835-6

PHP.eB

POS

Mouse, C57BL/6J

CNS, spinal cord neurons

hSyn

Sensor, ATeam

1E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.1038/s42255-023-00838-3

PHP.eB

POS

Mouse, Thy1-PercevalHR

CNS, spinal cord neurons

hSyn

Rescue, FP

1E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.1038/s42255-023-00838-3

PHP.eB

POS

Mouse, Thy1-PercevalHR

CNS, spinal cord neurons

hSyn

Recombinase, Cre, FP

1E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.1038/s42255-023-00838-3

PHP.eB

POS

Mouse, Ube3am+/p-

CNS, neurons

hSyn, U6

CRISPR, hfCas13x.1, crRNA

5E10 vg/animal

ICV

4 weeks

https://doi.org/10.1016/j.ymthe.2023.02.015

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, neurons

hSyn, U6

CRISPR, hfCas13x.1, crRNA

5E10 vg/animal

ICV

4 weeks

https://doi.org/10.1016/j.ymthe.2023.02.015

PHP.eB

POS

Mouse, Ube3am+/p- neonate

CNS, all

CAG

FP

3E10 vg/animal

ICV

3 weeks

https://doi.org/10.1016/j.ymthe.2023.02.015

PHP.eB

NEG

Mouse, Ube3am+/p- neonate

CNS, all

CAG

FP

1.9E11 vg/animal

Facial vein

3 weeks

https://doi.org/10.1016/j.ymthe.2023.02.015

PHP.eB

POS

Mouse, R6/2

CNS, all

Ef1a

FP

Tail vein

4 weeks

https://doi.org/10.1038/s41467-023-39552-9

PHP.eB

POS

Mouse, R6/2

CNS, all

Ef1a

Rescue

Tail vein

4 weeks

https://doi.org/10.1038/s41467-023-39552-9

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG

Ef1a, U6

shRNA, FP

2.5E12 vg/animal

Intrathecal, lumbar

3 weeks

https://doi.org/10.1126/sciadv.adi0286

PHP.B

POS

Mouse, LSL-Cas9

CNS, all

CBh, U6

Recombinase, Cre, FP, CRISPR, sgRNA, Perturb-Seq

5E9 vg/animal

Tail vein

4 weeks

https://doi.org/10.1038/s41586-023-06570-y

PHP.B

POS

Mouse, LSL-Cas9

CNS, all

CBh

FP

2.5E9 vg/animal

Tail vein

4 weeks

https://doi.org/10.1038/s41586-023-06570-y

PHP.B

POS

Mouse, LSL-Cas9

CNS, all

CBh

FP

5E9 vg/animal

Tail vein

4 weeks

https://doi.org/10.1038/s41586-023-06570-y

PHP.B

POS

Mouse, LSL-Cas9

CNS, all

CBh

FP

2.5E10 vg/animal

Tail vein

4 weeks

https://doi.org/10.1038/s41586-023-06570-y

PHP.B

POS

Mouse, dCas9-KRAB

CNS, all

U6

CRISPRi, gRNA

5E9 vg/animal

Tail vein

4 weeks

https://doi.org/10.1038/s41586-023-06570-y

PHP.B

POS

Mongolian gerbil

Cochlea, spiral ganglion neurons

hSyn

Opsin, CatCh, FP

~1E10 vg/site

Cochlea spiral ganglion

4 weeks

https://doi.org/10.1016/j.brs.2023.09.018

PHP.eB

POS

Mongolian gerbil

Cochlea, spiral ganglion neurons

hSyn

Opsin, CatCh, FP

~1E10 vg/site

Cochlea spiral ganglion

4 weeks

https://doi.org/10.1016/j.brs.2023.09.018

PHP.B

POS

Mouse, YG8sR

CNS, all

UBC, U6

shRNA, FP

1.2E12 vg/animal

Tail vein

5 weeks

https://doi.org/10.3390/genes14081654

PHP.B

POS

Mouse, YG8sR

CNS, all

UBC, U6

shRNA, FP

2.4E12 vg/animal

Tail vein

5 weeks

https://doi.org/10.3390/genes14081654

PHP.B

POS

Mouse, YG8sR

CNS, all

UBC, U6

shRNA, FP

3E11 vg/animal

Tail vein

5 weeks

https://doi.org/10.3390/genes14081654

PHP.B

POS

Mouse, YG8sR

CNS, all

UBC, U6

shRNA, FP

6E11 vg/animal

Tail vein

5 weeks

https://doi.org/10.3390/genes14081654

PHP.B

POS

Mouse, YG8sR

CNS, neurons

hSyn

Rescue

Tail vein

5 weeks

https://doi.org/10.3390/genes14081654

PHP.B

POS

Mouse, YG8sR

CNS, all

CBh

Rescue

Tail vein

5 weeks

https://doi.org/10.3390/genes14081654

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

U6

shRNA

1.4E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1007/s10571-023-01420-x

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

Sensor, Flamindo2

1E11 vg/animal

RO

https://doi.org/10.3389/fimmu.2023.1273837

PHP.AX

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

Sensor, Flamindo2

1E11 vg/animal

RO

https://doi.org/10.3389/fimmu.2023.1273837

PHP.S

POS

Rat, Sprague-Dawley

CNS, spinal cord neurons, PNS, DRG, MPG, sympathetic chain ganglia, inferior mesenteric ganglia

hSyn1

FP

1E13 vg/animal

Tail vein

3 weeks

https://doi.org/10.1096/fj.202301113R

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG

CAG

FP

Intraarticular

4 weeks

https://doi.org/10.1126/scitranslmed.adh3839

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG

CAG

Chemogenetic, PSAM4-GlyR, FP

Intraarticular

4 weeks

https://doi.org/10.1126/scitranslmed.adh3839

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

Sensor, Gluc-RMA

5E12 vg/kg

Tail vein

3 weeks

https://doi.org/10.1038/s41587-023-02087-x

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

Sensor, Gluc-RMA

5E12 vg/kg

Tail vein

5 weeks

https://doi.org/10.1038/s41587-023-02087-x

PHP.B

POS

Mouse, ICR neonate

Cochlea, inner hair cells IHC, outer hair cells OHC

CAG

FP

1E10 vg/site

Round window membrane

4 weeks

https://doi.org/10.1038/s41434-023-00431-z

PHP.eB

POS

Mouse, ICR neonate

Cochlea, inner hair cells IHC, outer hair cells OHC

CAG

FP

1E10 vg/site

Round window membrane

4 weeks

https://doi.org/10.1038/s41434-023-00431-z

PHP.eB

POS

Mouse, Dyrk1a+/+

CNS, parvalbumin neurons

S5E2

FP

Intracranial, hippocampus

2 weeks

https://doi.org/10.1016/j.neuron.2023.09.009

PHP.eB

POS

Mouse, Dyrk1a+/-

CNS, parvalbumin neurons

S5E2

FP

Intracranial, hippocampus

2 weeks

https://doi.org/10.1016/j.neuron.2023.09.009

PHP.eB

POS

Mouse, Dyrk1a+/+

CNS, parvalbumin neurons

S5E2

Chemogenetic, hM3Dq, FP

Intracranial, hippocampus

2-3 weeks

https://doi.org/10.1016/j.neuron.2023.09.009

PHP.eB

POS

Mouse, Dyrk1a+/-

CNS, parvalbumin neurons

S5E2

Chemogenetic, hM3Dq, FP

Intracranial, hippocampus

2-3 weeks

https://doi.org/10.1016/j.neuron.2023.09.009

PHP.eB

POS

Mouse, Tie2-Cre

CNS

CAG FLEX

FP

2.6E11 vg/animal

RO

2 weeks

https://doi.org/10.14336/AD.2023.1213

PHP.eB

POS

Mouse, Tie2-Cre

CNS

CAG FLEX

Rescue, FP

2.6E11 vg/animal

RO

2 weeks

https://doi.org/10.14336/AD.2023.1213

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

EF1a

FP

Intracranial, striatum

7 days

https://doi.org/10.14336/AD.2023.1213

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

EF1a

FP

2.6E11 vg/animal

RO

7 days

https://doi.org/10.14336/AD.2023.1213

PHP.N

POS

Mouse, EMX1-Cre

CNS, V1 S1

hSyn1 FLEX

Sensor, CaMPARI2

2E7 vg/site

Intracranial

3 weeks

https://doi.org/10.1038/s41467-023-42083-y

PHP.N

POS

Moue, B6 PVcre

CNS, V1 S1

hSyn1 FLEX

Sensor, CaMPARI2

2E7 vg/site

Intracranial

3 weeks

https://doi.org/10.1038/s41467-023-42083-y

PHP.S

POS

Rat, Sprague-Dawley

PNS, trigeminal ganglion neurons

CAG

FP

2E10 vg/site

lingual mucosa

4 weeks

https://doi.org/10.1002/cne.25584

PHP.S

POS

Rat, Sprague-Dawley

PNS, trigeminal ganglion neurons

CAG

FP

2E10 vg/site

scalp

4 weeks

https://doi.org/10.1002/cne.25584

PHP.S

POS

Rat, Sprague-Dawley

PNS, trigeminal ganglion neurons

CAG

FP

2E10 vg/site

masseter muscle

4 weeks

https://doi.org/10.1002/cne.25584

PHP.eB

POS

Mouse, Piga+/- neonate

CNS, all

CAG

Rescue

1E11 vg/animal

temporal vein

1 week

https://doi.org/10.1016/j.omtm.2023.101176

PHP.eB

POS

Mouse, Piga- neonate

CNS, all

CAG

Rescue

1E11 vg/animal

temporal vein

1 week

https://doi.org/10.1016/j.omtm.2023.101176

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

MiniLAP2

FP

5E11 vg/animal

RO

30 days

https://doi.org/10.1038/s41434-023-00430-0

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

LAP2

FP

5E11 vg/animal

RO

30 days

https://doi.org/10.1038/s41434-023-00430-0

PHP.eB

POS

Mouse, C57BL/6N

CNS, all

CAG

FP

1E11 vg/animal

RO

15 days

https://doi.org/10.1186/s13024-023-00683-8

PHP.eB

POS

Mouse, C57BL/6N

CNS, all

CAG

Rescue

1E11 vg/animal

RO

15 days

https://doi.org/10.1186/s13024-023-00683-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, excitatory neurons

CaMKIIa

Recombinase, Cre, FP

ICV

4 weeks

https://doi.org/10.3389/fncel.2023.1267609

PHP.eB

POS

Mouse, REST-cKO

CNS, excitatory neurons

CaMKIIa

FP

ICV

4 weeks

https://doi.org/10.3389/fncel.2023.1267609

PHP.eB

POS

Mouse, REST-cKO

CNS, excitatory neurons

CaMKIIa

Recombinase, Cre, FP

ICV

4 weeks

https://doi.org/10.3389/fncel.2023.1267609

PHP.eB

POS

Mouse, SOD1G93A

CNS, brain spinal cord

hSyn

FP

5E11 vg/animal

Intrathecal, lumbar

3 weeks

https://doi.org/10.1016/j.ymthe.2023.09.018

PHP.eB

POS

Mouse, SOD1G93A

CNS, brain spinal cord

CBh

FP

5E11 vg/animal

Intrathecal, lumbar

3 weeks

https://doi.org/10.1016/j.ymthe.2023.09.018

PHP.eB

POS

Mouse, SOD1G93A

CNS, brain spinal cord

CBh

Rescue

5E11 vg/animal

Intrathecal, lumbar

3 weeks

https://doi.org/10.1016/j.ymthe.2023.09.018

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

pCALM1

FP

5E10 vg/animal

ICV

3 weeks

https://doi.org/10.1016/j.celrep.2023.113348

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

pCALM1

FP

5E11 vg/animal

ICV

3 weeks

https://doi.org/10.1016/j.celrep.2023.113348

PHP.B

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

FP

5E10 vg/animal

ICV

3 weeks

https://doi.org/10.1016/j.celrep.2023.113348

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

FP

5E10 vg/animal

ICV

3 weeks

https://doi.org/10.1016/j.celrep.2023.113348

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

5E10 vg/animal

ICV

3 weeks

https://doi.org/10.1016/j.celrep.2023.113348

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

pCALM1

FP

4E10 vg/animal

ICV

3 weeks

https://doi.org/10.1016/j.celrep.2023.113348

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

pCALM1

FP

1.6E9 vg/animal

ICV

3 weeks

https://doi.org/10.1016/j.celrep.2023.113348

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

pCALM1

FP

1E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.celrep.2023.113348

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

pCALM1

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.celrep.2023.113348

PHP.B

POS

NHP, macaca fascicularis

CNS, neurons

pCALM1

FP

1-3E10 vg/site

Intracranial, cortex putamen thalamus

7 weeks

https://doi.org/10.1016/j.celrep.2023.113348

PHP.B

POS

NHP, macaca fascicularis

CNS, neurons

pCALM1

FP

6E11 vg/animal

ICV

7 weeks

https://doi.org/10.1016/j.celrep.2023.113348

PHP.eB

POS

Mouse, IDUA W402X

CNS, all

U6

CRISPR, circ-arRNA

2E12 vg/animal

Tail vein

6 weeks

https://doi.org/10.1186/s13059-023-03086-6

PHP.eB

POS

Mouse, EMX1-Cre neonate

CNS, cortical excitatory neurons

EF1a DIO

Sensor, JEDI-1P-Kv2.1

2-4E9 vg/animal

ICV

4 weeks

https://doi.org/10.1038/s41467-023-41975-3

PHP.eB

POS

Mouse, EMX1-Cre neonate

CNS, cortical excitatory neurons

CAG

FP

3E9 vg/animal

ICV

4 weeks

https://doi.org/10.1038/s41467-023-41975-3

PHP.eB

POS

Mouse, Rbp4-Cre

CNS, L5 cortical pyramidal neurons

CAG DIO

Sensor, GCaMP6f

4.3E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.7554/eLife.91153.3

PHP.B

POS

Mouse, C57BL/6J

CNS, all

Cbh

Rescue, FP

2E11 vg/animal

RO

3 weeks

https://doi.org/10.3390/ijms25137205

PHP.B

POS

Mouse, C57BL/6J

CNS, all

Cbh

Rescue, FP

5E10 vg/animal

RO

4 weeks

https://doi.org/10.3390/ijms25137205

PHP.B

POS

Mouse, C57BL/6J

CNS, all

Cbh

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.3390/ijms25137205

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CBA

FP

1E11 vg/animal

IV

3 weeks

https://doi.org/10.1016/j.isci.2024.109777

PHP.eB

NEG

Mouse, BALB/cJ

CNS, all

CBA

FP

1E11 vg/animal

IV

3 weeks

https://doi.org/10.1016/j.isci.2024.109777

PHP.D

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.ymthe.2024.04.003

PHP.D

NEG

Mouse, BALB/cJ

CNS, all

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.ymthe.2024.04.003

PHP.eB

POS

Mouse, C57BL/6J neonate

Cochlea, inner hair cells IHC, outer hair cells OHC

mid-Myo15

FP

1E10 vg/site

Round window membrane

2 weeks

https://doi.org/10.34133/research.0341

PHP.eB

POS

Mouse, C57BL/6J neonate

Cochlea, inner hair cells IHC, outer hair cells OHC

Myo15

FP

1E10 vg/site

Round window membrane

2 weeks

https://doi.org/10.34133/research.0341

PHP.eB

POS

Mouse, C57BL/6J neonate

Cochlea, inner hair cells IHC, outer hair cells OHC

CMV

FP

1E10 vg/site

Round window membrane

2 weeks

https://doi.org/10.34133/research.0341

PHP.eB

POS

Mouse, Otof-/- neonate

Cochlea, inner hair cells IHC, outer hair cells OHC

mid-Myo15

Rescue, split intein

1E10 vg/site

Round window membrane

4 weeks

https://doi.org/10.34133/research.0341

PHP.eB

POS

Mouse, C57BL/6J neonate

Cochlea, inner hair cells IHC, outer hair cells OHC

mini-Myo15-1

FP

1E10 vg/site

Round window membrane

2 weeks

https://doi.org/10.34133/research.0341

PHP.eB

NEG

Mouse, C57BL/6J neonate

Cochlea, inner hair cells IHC, outer hair cells OHC

mini-Myo15-2

FP

1E10 vg/site

Round window membrane

2 weeks

https://doi.org/10.34133/research.0341

PHP.eB

POS

Mouse, Otof-/- neonate

Cochlea, inner hair cells IHC, outer hair cells OHC

mid-Myo15

Rescue, split intein

1E10 vg/site

Round window membrane

4 weeks

https://doi.org/10.34133/research.0341

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

Gluc-RMA

5E9 vg/g

tail vein

3 weeks

https://doi.org/10.1038/s41587-023-02087-x

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

Gluc-RMA

5E9 vg/g

tail vein

5 weeks

https://doi.org/10.1038/s41587-023-02087-x

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

Gluc-RMA

1.2E9 vg/g

tail vein

3 weeks

https://doi.org/10.1038/s41587-023-02087-x

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

Gluc-RMA

1.2E9 vg/g

tail vein

5 weeks

https://doi.org/10.1038/s41587-023-02087-x

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

Gluc-RMA

5E8 vg/g

tail vein

3 weeks

https://doi.org/10.1038/s41587-023-02087-x

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

Gluc-RMA

5E8 vg/g

tail vein

5 weeks

https://doi.org/10.1038/s41587-023-02087-x

PHP.S

POS

Mouse, C57BL/6J neonate

PNS, DRG neurons

hSyn1

Sensor, opto-iTrkA

5E10 vg/animal

Intraperitoneal, IP

8 months

https://doi.org/10.1021/acschembio.4c00300

PHP.S

POS

Mouse, C57BL/6J neonate

PNS, DRG neurons

hSyn1

FP

5E10 vg/animal

Intraperitoneal, IP

8 months

https://doi.org/10.1021/acschembio.4c00300

PHP.S

POS

Rat, Sprague-Dawley

PNS, DRG, major pelvic ganglia (MPG)

hSyn1

FP

1E13 vg/animal

tail vein

3 weeks

https://doi.org/10.1096/fj.202301113R

PHP.S

NEG

Rat, Sprague-Dawley

CNS, spinal cord neurons

hSyn1

FP

1E13 vg/animal

tail vein

3 weeks

https://doi.org/10.1096/fj.202301113R

PHP.eB

POS

Mouse, FVB

CNS, astrocytes

GFAP

shRNA, FP

5E8 vg/site

Intracranial, cortex

2 months

https://doi.org/10.4103/1673-5374.390957

PHP.eB

POS

Mouse, C57BL/6N

CNS, parvalbumin neurons

E11

FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, C57BL/6N

CNS, parvalbumin neurons

E11

Rescue

5E10 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, C57BL/6N

CNS, parvalbumin neurons

E11

Chemogenetic, hM3Dq, FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, C57BL/6N

CNS, parvalbumin neurons

E11

Chemogenetic, hM4Di, FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, C57BL/6N

CNS, parvalbumin neurons

E22

Chemogenetic, hM4Di, FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, C57BL/6N

CNS, parvalbumin neurons

E22

Chemogenetic, hM3Dq, FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, C57BL/6N

CNS, parvalbumin neurons

E22

FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, C57BL/6N

CNS, parvalbumin neurons

E11

FP

5E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, C57BL/6N

CNS, parvalbumin neurons

E11

FP

3E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, C57BL/6N

CNS, parvalbumin neurons

E11

shRNA, FP

3E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, C57BL/6N

CNS, parvalbumin neurons

E11

FP

5E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, C57BL/6N

CNS, parvalbumin neurons

E11

shRNA, FP

5E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, Pvalb−2A-Cre

CNS, parvalbumin neurons

E11 DIO

FP

1.5E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, Pvalb−2A-Cre

CNS, parvalbumin neurons

E11 DIO

shRNA, FP

1.5E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, C57BL/6N

CNS, parvalbumin neurons

E11

Rescue

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, Pvalb−2A-Cre

CNS, parvalbumin neurons

E11 DIO

Rescue

5E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, Pvalb−2A-Cre

CNS, parvalbumin neurons

hSyn DIO

Rescue

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, Vglut2-ires-Cre

CNS, excitatory neurons

hSyn DIO

Rescue

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41467-024-50168-5

PHP.eB

POS

Mouse, B6.129S1-Fbln2tm1Chu/J WT

CNS, astrocytes

GFAP, U6

CRISPR, sgRNA, FP

3E11 vg/animal

RO

2 weeks

https://doi.org/10.1172/JCI176910

PHP.eB

POS

Mouse, B6.129S1-Fbln2tm1Chu/J WT

CNS, astrocytes

GFAP

CRISPR, SaCas9

3E11 vg/animal

RO

2 weeks

https://doi.org/10.1172/JCI176910

PHP.eB

POS

Mouse, C57BL/6N

CNS, neurons

EFS

Epigenetic editor, Zfcharm Kv1

1.5E13 vg/kg

RO

6 weeks

https://doi.org/10.1126/science.ado7082

PHP.eB

POS

Mouse, C57BL/6N

CNS, neurons

EFS

Epigenetic editor, Zfcharm

1.5E13 vg/kg

RO

6 weeks

https://doi.org/10.1126/science.ado7082

PHP.eB

POS

Mouse, C57BL/6N

CNS, neurons

EFS

Epigenetic editor, Zfcharm Kv1

0.75E13 vg/kg

RO

6 weeks

https://doi.org/10.1126/science.ado7082

PHP.eB

POS

Mouse, C57BL/6N

CNS, neurons

EFS

Epigenetic editor, Zfcharm Kv1

3E13 vg/kg

RO

6 weeks

https://doi.org/10.1126/science.ado7082

PHP.eB

POS

Mouse, C57BL/6N

CNS, neurons

EFS

Epigenetic editor, Zfcharm Kv1

3E13 vg/kg

RO

6 weeks

https://doi.org/10.1126/science.ado7082

PHP.eB

POS

Mouse, C57BL/6N

CNS, neurons

EFS

Epigenetic editor, Zfcharm Kv1 self-silence

1.5E13 vg/kg

RO

6 weeks

https://doi.org/10.1126/science.ado7082

PHP.S

NEG

Mouse, C57BL/6J

PNS, DRG, Nodose

hSyn

FP

1E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.celrep.2024.113953

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG, Nodose

CAG

FP

1E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.celrep.2024.113953

PHP.S

NEG

Mouse, C57BL/6J

PNS, DRG Th+ neurons

hSyn

FP

1E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.celrep.2024.113953

PHP.S

NEG

Mouse, C57BL/6J

PNS, DRG Th+ neurons

CAG

FP

1E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.celrep.2024.113953

PHP.S

NEG

Mouse, C57BL/6J

PNS, Nodose Th+ neurons

hSyn

FP

1E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.celrep.2024.113953

PHP.S

POS

Mouse, C57BL/6J

PNS, Nodose Th+ neurons

CAG

FP

1E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.celrep.2024.113953

PHP.S

NEG

Mouse, C57BL/6J

CNS, brain, spinal cord

hSyn

FP

1E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.celrep.2024.113953

PHP.S

POS

Mouse, C57BL/6J

PNS, ENS (except medial colon)

hSyn

FP

1E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.celrep.2024.113953

PHP.S

POS

Mouse, ChAT-Cre

PNS, ENS

hSyn DIO

Chemogenetic, hM3Dq, FP

1E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.celrep.2024.113953

PHP.S

POS

Mouse, TH-Cre

PNS, ENS

hSyn DIO

Chemogenetic, hM3Dq, FP

1E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.celrep.2024.113953

PHP.S

POS

Mouse, ChAT-Cre

PNS, ENS

hSyn DIO

FP

1E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.celrep.2024.113953

PHP.S

POS

Mouse, TH-Cre

PNS, ENS

hSyn DIO

FP

1E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.celrep.2024.113953

PHP.eB

POS

Mouse, Gucy2d

CNS, neurons

CAG FLEX

FP

1E11 vg/animal

retrobulbar sinus

3 weeks

https://doi.org/10.1371/journal.pone.0300282

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CMV, EF1a

shRNA, FP

caudal vein

1 month

https://doi.org/10.1007/s10571-023-01435-4

PHP.eB

POS

Mouse, B6;129-Glatm1Kul/J

CNS, all

CMV

Rescue

5E12 vg/kg

Tail vein

7 months

https://doi.org/10.1016/j.ymgme.2024.108545

PHP.eB

POS

Mouse, B6;129-Glatm1Kul/J

CNS, all, PNS, DRG

CMV

Rescue

5E12 vg/kg

intrathecal

7 months

https://doi.org/10.1016/j.ymgme.2024.108545

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, spinal cord

FP

1E11 vg/animal

Facial vein

3 weeks

https://doi.org/10.1038/s41467-024-50095-5

PHP.eB

POS

Mouse, Ai14-Cas9 neonate

CNS, spinal cord

CMV, U6

FP, CRISPR, sgRNA

1E11 vg/animal

Facial vein

2 weeks

https://doi.org/10.1038/s41467-024-50095-5

PHP.eB

POS

Mouse, SMN2+/+; SMN_7+/+; Smn1_/_ neonate

CNS, spinal cord

CMV

CRISPR, SpCas9

1E11 vg/animal

Facial vein

2 weeks

https://doi.org/10.1038/s41467-024-50095-5

PHP.eB

POS

Mouse, SMN2+/+; SMN_7+/+; Smn1_/_ neonate

CNS, spinal cord

U6

CRISPR, sgRNA, FP

1E11 vg/animal

Facial vein

2 weeks

https://doi.org/10.1038/s41467-024-50095-5

PHP.eB

POS

Mouse, GluK4-Cre-ko

CNS, all

CAG FLEX

FP

1E12 vg/animal

RO

10-14 days

https://doi.org/10.1016/j.celrep.2024.114427

28304

PHP.eB

POS

Mouse, GluK4-Cre-ko

CNS, all

hSyn DIO

Rescue

1E12 vg/animal

RO

10-14 days

https://doi.org/10.1016/j.celrep.2024.114427

PHP.eB

POS

Mouse, GluK4-Cre-ko

CNS, all

hSyn DIO

FP

1E12 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.celrep.2024.114427

PHP.eB

POS

Mouse, GluK4-Cre-ko

CNS, all

hSyn

FP

1E12 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.celrep.2024.114427

PHP.eB

POS

Mouse, GluK4-Cre-ko

CNS, all

hSyn

Recombinase, Cre, FP

1E12 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.celrep.2024.114427

PHP.eB

POS

Mouse, GluK4-Cre-ko

CNS, all

L7

FP

1E12 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.celrep.2024.114427

PHP.eB

POS

Mouse, GluK4-Cre-ko

CNS, all

L7

Recombinase, Cre, FP

1E12 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.celrep.2024.114427

PHP.eB

POS

Mouse, C57BL/6J neonate

Cochlea neurons

CAG

FP

3E10 vg/site

Round window membrane

5 days

https://doi.org/10.1371/journal.pone.0305742

37825

PHP.eB

POS

Mouse, C57BL/6J embryos

Cochlea neurons

CAG

FP

3E10 vg/site

in utero

6 days

https://doi.org/10.1371/journal.pone.0305742

PHP.S/PHP.eB ?

POS

Mouse, Olig1 KO

CNS, spinal cord sciatic neurons

CBh, U6

CRISPR, CasRx, sgRNA

intrathecal

15 days

https://doi.org/10.1016/j.celrep.2024.114514

PHP.S/PHP.eB ?

POS

Mouse, Olig1 KO

CNS, spinal cord sciatic neurons

CBh

Rescue

intrathecal

15 days

https://doi.org/10.1016/j.celrep.2024.114514

PHP.eB

POS

Mouse, Mecp2G311A

CNS, all

U6

CRISPR, sgRNA ADAR

4E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41587-024-02313-0

PHP.eB

POS

Mouse, Vipr2-Cre neonate

EF1a DIO

Opsin, ChR2(H134R)-FP

intracranial, thalamus

6-35 days

https://doi.org/10.1038/s41467-024-49732-w

20298

PHP.eB

POS

Mouse, Cas9 KI neonate

hSyn, U6

CRISPR, sgRNA, FP

1E11 vg/animal

ICV

3 weeks

https://doi.org/10.1186/s12915-024-01940-y

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CMV

FP

1E11 vg/animal

RO

3 months

https://doi.org/10.1038/s44318-024-00156-8

PHP.eB

POS

Mouse, Gde2KO

CNS, all

CMV

FP

1E11 vg/animal

RO

3 months

https://doi.org/10.1038/s44318-024-00156-8

PHP.eB

POS

Mouse, Ctnnb-flex3

CNS, all

CMV

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s44318-024-00156-8

PHP.eB

POS

Mouse, Ctnnb-flex3

CNS, all

CMV

Recombinase, Cre, FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s44318-024-00156-8

PHP.eB

POS

Mouse, MG-Tgfb1 iKO

CNS, neurons

hSyn

FP

1E10 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-024-49596-0

PHP.S

POS

Mouse, C57BL/6J

PNS

CAG, U6

shRNA, FP

Tail vein

4 weeks

https://doi.org/10.1038/s41467-024-49577-3

PHP.S

POS

Mouse, Nav1.8Cre

PNS

EF1a DIO, U6

shRNA, FP

Tail vein

4 weeks

https://doi.org/10.1038/s41467-024-49577-3

PHP.eB

POS

Mouse, Spg11_/_

CNS, all

CMV

shRNA, FP

3E12 vg/animal

caudal vein

3 weeks

https://doi.org/10.1016/j.nbd.2024.106564

PHP.eB

POS

Mouse, Spg11+/+

CNS, all

CMV

shRNA, FP

3E12 vg/animal

caudal vein

3 weeks

https://doi.org/10.1016/j.nbd.2024.106564

PHP.eB

POS

Mouse, SOD1G93A;En1cre

CNS, lumbar spinal cord, midbrain, somatosensory cortex

hSyn DIO

Rescue

3E11 vg/animal

RO

40 days

https://doi.org/10.1038/s41467-024-48925-7

PHP.eB

POS

Mouse, En1cre

CNS, lumbar spinal cord, midbrain, somatosensory cortex

hSyn DIO

FP

3E11 vg/animal

RO

40 days

https://doi.org/10.1038/s41467-024-48925-7

PHP.eB

POS

Mouse, SOD1G93A

CNS, lumbar spinal cord, midbrain, somatosensory cortex

hSyn

FP

3E11 vg/animal

RO

40 days

https://doi.org/10.1038/s41467-024-48925-7

PHP.eB

POS

Mouse, Aldh1l1-Cas9

CNS, astrocytes

U6

CRISPR, sgRNA

2-4E9 vg/site

Intracranial, hippocampus

1 week

https://doi.org/10.1016/j.celrep.2024.114278

PHP.eB

POS

Mouse, Aldh1/1-Cre

CNS, astrocytes

hGfaABC1D-DIO

Rescue

4E9 vg/site

Intracranial, hippocampus

5 weeks

https://doi.org/10.1016/j.celrep.2024.114278

PHP.eB

POS

Mouse, Aldh1/1-Cre

CNS, astrocytes

hGfaABC1D-DIO

Chemogenetic, hM4Di

5E9 vg/site

Intracranial, hippocampus

1 week

https://doi.org/10.1016/j.celrep.2024.114278

PHP.eB

POS

Mouse, Aldh1/1-Cre

CNS, astrocytes

hGfaABC1D-DIO

Chemogenetic, rM3Ds

5E9 vg/site

Intracranial, hippocampus

1 week

https://doi.org/10.1016/j.celrep.2024.114278

PHP.eB

POS

Mouse, Aldh1l1-Cas9

CNS, astrocytes

hGfaABC1D-DIO

Chemogenetic, hM4Di

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.celrep.2024.114278

PHP.eB

POS

Mouse, Aldh1l1-Cas9

CNS, astrocytes

hGfaABC1D-DIO

Chemogenetic, rM3Ds

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.celrep.2024.114278

PHP.eB

POS

Mouse, CamkII_-Pfkfb3

CNS, neurons

hSyn

FP

RO

4 weeks

https://doi.org/10.1038/s42255-024-01049-0

PHP.eB

POS

Mouse, Pfkfb3lox/+

CNS, neurons

CaMKIIa

Recombinase, Cre, FP

5E10 vg/animal

RO

4 weeks

https://doi.org/10.1038/s42255-024-01049-0

PHP.eB

POS

Mouse, Pfkfb3lox/+

CNS, neurons

CaMKIIa

FP

5E10 vg/animal

RO

4 weeks

https://doi.org/10.1038/s42255-024-01049-0

PHP.eB

POS

Mouse, C57BL/6J

Retina

CAG

FP

2-3E11 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.cell.2024.04.010

PHP.S

POS

Mouse, C57BL/6J

Retina

CAG

FP

2-3E11 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.cell.2024.04.010

PHP.eB

POS

Mouse, SOM-cre

CNS, neurons

CAG

Sensor, GCaMP7f

1E12 vg/animal

RO

2-3 weeks

https://doi.org/10.1038/s41593-024-01647-x

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

2.7E11 vg/animal

RO

https://doi.org/10.1016/j.neuron.2024.02.011

37825

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Sensor, jRCaMP1b

2.25E12 vg/animal

RO

3 weeks

https://doi.org/10.3389/fncel.2024.1258793

PHP.S

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Rescue, FP

Intracranial, cortex

2 weeks

https://doi.org/10.1083/jcb.202206046

PHP.B

POS

Mouse, APP/PS1

CNS, all

CMV

Rescue

1.2E11 vg/animal

tail vein

3 months

https://doi.org/10.4103/NRR.NRR-D-23-01277

PHP.eB

POS

Mouse, RestGTi neonate

hSyn

Recombinase, Cre, FP

2E8 - 2E9 vg/animal

ICV

1-4 weeks

https://doi.org/10.1111/apha.14146

PHP.eB

POS

Mouse, RestGTi neonate

hSyn

FP

2E8 - 2E9 vg/animal

ICV

1-4 weeks

https://doi.org/10.1111/apha.14146

PHP.eB

POS

Mouse, SCA7140Q/5Q

CNS, all

CMV, H1

shRNA, FP

1.5E12 vg/kg

RO

5 weeks

https://doi.org/10.3390/ijms25084354

PHP.eB

POS

Mouse, SCA7140Q/5Q

CNS, all

CMV, H1

shRNA, FP

5E12 vg/kg

RO

5 weeks

https://doi.org/10.3390/ijms25084354

PHP.eB

POS

Mouse, SCA7140Q/5Q

CNS, all

CMV, H1

shRNA, FP

1.5E13 vg/kg

RO

5 weeks

https://doi.org/10.3390/ijms25084354

PHP.eB

POS

Mouse, APP/PS1

CNS, all

CAG

Rescue

4.8E12 vg/animal

tail vein

5 months

https://doi.org/10.1002/trc2.12470

PHP.eB

POS

Mouse, Rosa26-TurboID/wt

CNS, parvalbumin interneurons

E2

Recombinase, Cre, FP

2.4E11 vg/animal

RO

5 weeks

https://doi.org/10.1038/s41467-024-47028-7

PHP.eB

POS

Mouse, Rosa26-TurboID/wt

FLEX

FP

3.2E11 vg/animal

RO

5 weeks

https://doi.org/10.1038/s41467-024-47028-7

PHP.eB

POS

Mouse, 5xFAD/PV-CIBOP

CNS, parvalbumin interneurons

E2

Recombinase, Cre, FP

2.4E11 vg/animal

RO

5 weeks

https://doi.org/10.1038/s41467-024-47028-7

PHP.eB

POS

Mouse, C57BL/6N

CNS, neurons

CaMKIIa

Recombinase, Cre

3E8 vg/site

intracranial, cortex

2 weeks

https://doi.org/10.1038/s41592-024-02222-9

PHP.eB

POS

Mouse, C57BL/6N

CNS, neurons

hSyn

FP

5E9 vg/site

intracranial, cortex

2 weeks

https://doi.org/10.1038/s41592-024-02222-9

PHP.eB

POS

Mouse, Pvalb-Cre +/-

CNS, parvalbumin neurons

hSyn DIO

Chemogenetic, hM4Di, FP

2.3E11 vg/mouse

RO

4 weeks

https://doi.org/10.1152/jn.00445.2023

PHP.eB

POS

Mouse, Pvalb-Cre +/-

CNS, parvalbumin neurons

hSyn DIO

Chemogenetic, hM3Dq, FP

2.3E11 vg/mouse

RO

4 weeks

https://doi.org/10.1152/jn.00445.2023

PHP.eB

POS

Mouse, Clrn2_/_ neonate

Cochlea neurons

CMV

Rescue, FP

Round window membrane

4 weeks

https://doi.org/10.1016/j.ymthe.2024.01.021

PHP.eB

POS

Mouse, Clrn2_/_ neonate

Cochlea neurons

CMV

FP

Round window membrane

4 weeks

https://doi.org/10.1016/j.ymthe.2024.01.021

PHP.eB

POS

Mouse, VIP-Cre 5xFAD

CNS, VIP neurons

hSyn DIO

Chemogenetic, hM4Di, FP

RO

3 weeks

https://doi.org/10.1038/s41586-024-07132-6

PHP.eB

POS

Mouse, ICR neonate

Cochlea

Myo15

FP

1E10 vg/site

Round window membrane

2 weeks

https://doi.org/10.1016/j.omtn.2024.102135

PHP.eB

POS

Mouse, ICR neonate

Cochlea

CAG

FP

1E10 vg/site

Round window membrane

2 weeks

https://doi.org/10.1016/j.omtn.2024.102135

PHP.eB

POS

Mouse, ICR

Cochlea

Myo15

FP

1E10 vg/site

Round window membrane

2 weeks

https://doi.org/10.1016/j.omtn.2024.102135

PHP.eB

POS

Mouse, ICR

Cochlea

CAG

FP

1E10 vg/site

Round window membrane

2 weeks

https://doi.org/10.1016/j.omtn.2024.102135

PHP.eB

POS

Mouse, Otof-/- neonate

Cochlea

Myo15

Rescue, intein

2E10 vg/site

Round window membrane

3-4 weeks

https://doi.org/10.1016/j.omtn.2024.102135

PHP.eB

POS

Mouse, Otof-/- neonate

Cochlea

CAG

Rescue, intein

2E10 vg/site

Round window membrane

3-4 weeks

https://doi.org/10.1016/j.omtn.2024.102135

PHP.eB

POS

Mouse, tRNAAla m.5024C>T

CNS, neurons

hSyn

TALEN

4E13 vg/kg

RO

6 weeks

https://doi.org/10.1016/j.omtn.2024.102132

PHP.eB

POS

Mouse, tRNAAla m.5024C>T

CNS, neurons

hSyn

FP

2-4E13 vg/kg

RO

6 weeks

https://doi.org/10.1016/j.omtn.2024.102132

PHP.eB

POS

Mouse, tRNAAla m.5024C>T

CNS, all

CBh

FP

2-4E13 vg/kg

RO

6 weeks

https://doi.org/10.1016/j.omtn.2024.102132

PHP.eB

POS

Mouse, tRNAAla m.5024C>T

CNS, all

CMV

FP

2-4E13 vg/kg

RO

6 weeks

https://doi.org/10.1016/j.omtn.2024.102132

PHP.eB

POS

Mouse, tRNAAla m.5024C>T

CNS, neurons

hSyn

TALEN

4E13 vg/kg

RO

24 weeks

https://doi.org/10.1016/j.omtn.2024.102132

PHP.eB

POS

Mouse, PKCgamma-null

CNS, purkinje neurons

L7-6-minCMV

Rescue, FP

5E11 vg/animal

RO

4 weeks

https://doi.org/10.3389/fncel.2024.1349878

PHP.eB

POS

Mouse, Plp1-Cre/ERT

CNS, sciatic nerve

CMV DIO, U6

CRISPR sgRNA, saCas9

direct injection

https://doi.org/10.1016/j.celrep.2024.113753

PHP.eB

POS

Mouse, Plp1-Cre/ERT

CNS, sciatic nerve schwann cells

MBP

Rescue

direct injection

2 weeks

https://doi.org/10.1016/j.celrep.2024.113753

PHP.S

POS

Rat, Sprague-Dawley

PNS, trigeminal ganglion neurons

CAG

FP

2E10 vg/site

direct injection, lingual mucosa

https://doi.org/10.1002/cne.25584

PHP.S

POS

Rat, Sprague-Dawley

PNS, trigeminal ganglion neurons

CAG

FP

2E10 vg/site

direct injection, scalp

https://doi.org/10.1002/cne.25584

PHP.S

POS

Rat, Sprague-Dawley

PNS, trigeminal ganglion neurons

CAG

FP

2E10 vg/site

direct injection, masseter muscle

https://doi.org/10.1002/cne.25584

PHP.S

POS

Rat, Sprague-Dawley

PNS, trigeminal ganglion neurons

CAG

FP

2E10 vg/site

direct injection, temporal muscle

https://doi.org/10.1002/cne.25584

PHP.S

POS

Mouse, Piezo1flox-flox

PNS, DRG

hSyn

Recombinase, Cre, FP

intrathecal, thoracic

3 weeks

https://doi.org/10.1161/CIRCULATIONAHA.123.065390

PHP.S

POS

Mouse, Piezo1flox-flox

PNS, DRG

hSyn

FP

intrathecal, thoracic

3 weeks

https://doi.org/10.1161/CIRCULATIONAHA.123.065390

PHP.S

POS

Mouse, Piezo1flox-flox

PNS, DRG

hSyn

shRNA, FP

intrathecal, thoracic

3 weeks

https://doi.org/10.1161/CIRCULATIONAHA.123.065390

PHP.eB

POS

Mouse, Ai14

CNS, astrocytes

mGfaABC1D

Recombinase, Cre

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2024.101185

PHP.eB

POS

Mouse, Ai14

CNS, astrocytes

mGfaABC1D

Recombinase, Cre

4E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2024.101185

PHP.eB

POS

Mouse, Ai14

CNS, astrocytes

mGfaABC1D

Recombinase, FlpO

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2024.101185

PHP.eB

POS

Mouse, Ai14

CNS, astrocytes

mGfaABC1D

Recombinase, dCre

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2024.101185

PHP.eB

POS

Mouse, Ai75G

CNS, neurons

NSE

Recombinase, Cre

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2024.101185

PHP.eB

POS

Mouse, Ai75G

CNS, neurons

NSE

Recombinase, FlpO

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2024.101185

PHP.eB

POS

Mouse, Ai75G

CNS, neurons

NSE

Recombinase, dCre

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2024.101185

PHP.B

POS

Mouse, hALD

CNS, all

CMV, U6

CRISPR, base editor, intein

6.4E12 vg/animal

Tail vein

6 weeks

https://doi.org/10.1016/j.ymthe.2024.05.027

PHP.B

POS

Mouse, hALD

CNS, all

CMV, U6

CRISPR, base editor, intein

1E12 vg/animal

Tail vein

6 weeks

https://doi.org/10.1016/j.ymthe.2024.05.027

PHP.B

POS

Mouse, hALD

CNS, all

CMV

FP

1E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.1016/j.ymthe.2024.05.027

PHP.eB

POS

Mouse, SM22_-Cre

CNS, vasculature

CAG FLEX

Rescue, FP

1.8E11 vg/site

ICV

6 weeks

https://doi.org/10.1038/s41551-024-01210-w

PHP.B

POS

Mouse, C57BL/6J neonate

CNS, all

CAG

Rescue

1.5E11 vg/animal

temporal vein

https://doi.org/10.1016/j.neuron.2024.01.022

PHP.B

POS

Mouse, iTDP-43A315T

CNS, all

CAG

Rescue

5E12 vg/animal

Tail vein

2 weeks

https://doi.org/10.1016/j.neuron.2024.01.022

PHP.eB

POS

Mouse, Rbp4-Cre

CNS, L5 pyramidal neurons

CAG DIO

Sensor, GCaMP6f

4.3E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.7554/eLife.91153.3

PHP.eB

POS

Mouse, Ngly1 fl/fl

CNS, all

CAG

Rescue

1.5E12 vg/animal

tail vein

8 weeks

https://doi.org/10.1172/jci.insight.183189

PHP.eB

POS

Mouse, Ngly1 fl/fl

CNS, all

CAG

Rescue

1.5E12 vg/animal

tail vein

12 months

https://doi.org/10.1172/jci.insight.183189

AAV1-X1

POS

Mouse, LRP6 fl/fl

CNS, endothelial

EF1a

Recombinase, Cre

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-024-52149-0

AAV1-X1

POS

Mouse, LRP6 fl/fl

CNS, endothelial

EF1a

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-024-52149-0

AAV9-X1.1

POS

Mouse, LRP6 fl/fl

CNS, endothelial

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-024-52149-0

PHP.eB

POS

Mouse, LRP6 fl/fl

CNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-024-52149-0

AAV9-X1.1

NEG

Mouse, LRP6 fl/fl + Cre

CNS, endothelial

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-024-52149-0

PHP.eB

POS

Mouse, LRP6 fl/fl + Cre

CNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-024-52149-0

AAV9-X1.1

POS

Human, iPSC neuron culture

CNS, neurons

CAG

FP

5E4 vg/cell

Direct application to culture

2 weeks

https://doi.org/10.1038/s41467-024-52149-0

PHP.eB

POS

Mouse,Xpr1-HA

CNS, astrocytes

gfaABC1D

FP

1E9 vg/site

Intracranial, thalamus

https://doi.org/10.1016/j.neuron.2024.06.020

PHP.eB

POS

Mouse, Pit2-KO

CNS, astrocytes

gfaABC1D

Rescue, FP

2E11 vg/animal

Tail vein or RO

3 months

https://doi.org/10.1016/j.neuron.2024.06.020

CAP-B10

POS

Mouse, C57BL/6J

CNS, neurons

CAG, U6

Sensor, tfLC3, shRNA

3.5-5E11 vg/animal

Tail vein

1 month

https://doi.org/10.1080/15548627.2024.2395727

PHP.eB

POS

Mouse, ndufs3-nKO

CNS, neurons

hSyn1

Rescue

2E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s44321-024-00111-4

PHP.eB

POS

Mouse, Cox10-nKO

CNS, neurons

hSyn1

Rescue

3.3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s44321-024-00111-4

PHP.eB

POS

Mouse, Cox10-nKO

CNS, neurons

hSyn1

FP

3.3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s44321-024-00111-4

PHP.eB

POS

Mouse, ndufs3-nKO

CNS, neurons

hSyn1

FP

2E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s44321-024-00111-4

PHP.eB

POS

Mouse, FVB

CNS, astrocytes

GFAP

shRNA, FP

2.5E9 vg/site

Intracranial, cortex

7-60 days

DOI: 10.4103/1673-5374.390957

PHP.eB

POS

Mouse, ICR

CNS, purkinje neurons

L7-6

Sensor, GCaMP7f

1E7 - 1.5E8 vg/site

Intracranial, cerebellum

7 days

https://doi.org/10.1038/s42003-024-07095-4

PHP.S

POS

Mouse, Piezo2-EGFP-IRES-Cre/+

PNS, piezo2+ sensory neurons

CAG FLEX

FP

5E9 vg/site

Direct injection, kidney

4 weeks

https://doi.org/10.1016/j.celrep.2024.114860

28306

PHP.eB

POS

Mouse, 129-E

Retina, rod photoreceptors

mOP

Rescue

Subretinal

3 months

https://doi.org/10.1371/journal.pone.0308058

PHP.eB

POS

Mouse, PAN-et

Retina, rod photoreceptors

mOP

Rescue

Subretinal

3 months

https://doi.org/10.1371/journal.pone.0308058

PHP.eB

POS

Mouse, ChAT-Cre

CNS, DMV cholinergic neurons

CAG FLEX

FP

Direct injection, liver

3 weeks

https://doi.org/10.1371/journal.pbio.3002865

28306

PHP.eB

POS

Mouse, Cas9 KI neonate

CNS, neurons

hSyn, U6

FP, CRISPR, sgRNA

1E11 vg/animal

ICV

8 weeks

https://doi.org/10.1038/s41598-024-70728-5

PHP.eB

POS

Mouse, Gal-Cre

CNS, SC Gal neurons

CMV FLEX

Rescue, FP

1E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1126/science.ado6593

PHP.S

NEG

Mouse, C57BL/6J

PNS, DRG

CAG

FP

1.5E10 vg/animal

Direct injection, L4 DRG

https://doi.org/10.1016/j.jneumeth.2024.110268

PHP.eB

POS

Mouse, H11-Cas9 neonate

CNS, all

U6

Proximity Label, TurboID, gRNA

2E10 vg/site

Intracranial, forebrain

3 weeks

https://doi.org/10.1038/s41467-024-51037-x

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Luciferase

8.3E9 vg/g

Tail vein

3-4 weeks

https://doi.org/10.1126/sciadv.adj7686

PHP.S

POS

Mouse, Trpv1-Cre

PNS, nodose DRG, enteric

hSyn DIO

Chemogenetic, hM3Dq, FP

2E11 vg/animal

Intraperitoneal, IP

https://doi.org/10.1126/science.adk1679

PHP.S

POS

Mouse, Piezo2-Cre

PNS, nodose DRG, enteric

hSyn DIO

Chemogenetic, hM3Dq, FP

2E11 vg/animal

Intraperitoneal, IP

https://doi.org/10.1126/science.adk1679

PHP.S

POS

Mouse, Mrgprd-Cre

PNS, nodose DRG, enteric

hSyn DIO

Chemogenetic, hM3Dq, FP

2E11 vg/animal

Intraperitoneal, IP

https://doi.org/10.1126/science.adk1679

PHP.S

POS

Mouse, Tac1-Cre

PNS, nodose DRG, enteric

hSyn DIO

Chemogenetic, hM3Dq, FP

2E11 vg/animal

Intraperitoneal, IP

https://doi.org/10.1126/science.adk1679

PHP.S

POS

Mouse, Th-Cre

PNS, nodose DRG, enteric

hSyn DIO

Chemogenetic, hM3Dq, FP

2E11 vg/animal

Intraperitoneal, IP

https://doi.org/10.1126/science.adk1679

PHP.S

POS

Mouse, CHAT-Cre

PNS, nodose DRG, enteric

hSyn DIO

Chemogenetic, hM3Dq, FP

2E11 vg/animal

Intraperitoneal, IP

https://doi.org/10.1126/science.adk1679

PHP.S

POS

Mouse, Vip-Cre

PNS, nodose DRG, enteric

hSyn DIO

Chemogenetic, hM3Dq, FP

2E11 vg/animal

Intraperitoneal, IP

https://doi.org/10.1126/science.adk1679

PHP.S

POS

Mouse, Nos1-Cre

PNS, nodose DRG, enteric

hSyn DIO

Chemogenetic, hM3Dq, FP

2E11 vg/animal

Intraperitoneal, IP

https://doi.org/10.1126/science.adk1679

PHP.eB

POS

Mouse, GLA-KO

CNS, all

CMV

Rescue

5E12 vg/kg

Tail vein

7 months

https://doi.org/10.1016/j.ymgme.2024.108545

PHP.eB

POS

Mouse, GLA-KO

CNS, all

CMV

Rescue

5E12 vg/kg

intrathecal, lumbar

7 months

https://doi.org/10.1016/j.ymgme.2024.108545

PHP.B

POS

Mouse, APP/PS1

CNS, all

CMV

FP

1E12 vg/animal

Tail vein

3 months

DOI: 10.4103/NRR.NRR-D-23-01277

PHP.B

POS

Mouse, APP/PS1

CNS, all

CMV

Rescue, FP

1E12 vg/animal

Tail vein

3 months

DOI: 10.4103/NRR.NRR-D-23-01277