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Repository of published systemic AAV experiments

yuky9
Updated April 28th 2022
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capsid Result Species Target Promoter Cargo Dose Injection Incubation Doi Addgene Genome

PHP.eB

POS

Mouse, C57BL6

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

104061

PHP.B

POS

Mouse, C57BL6

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

104061

PHP.S

NEG

Mouse, C57BL6

CNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

104061

PHP.S

POS

Mouse, C57BL6

PNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

104061

PHP.eB

POS

Mouse, C57BL6

CNS, astrocyte

GFAP

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

99129

PHP.eB

POS

Mouse, C57BL6

CNS, oligodendrocyte

MBP

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

PHP.eB

POS

Mouse, C57BL6

CNS, neuron

hSyn1

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

99135

PHP.eB

POS

Mouse, C57BL6

CNS, serotonergic neuron

Ple67

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4593

49138

PHP.eB

POS

Mouse, C57BL6

CNS, catecholaminergic neuron

mTH

FP

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/nn.4593

99128

PHP.eB

POS

Mouse, C57BL6

CNS, purkinje neuron

Ple155

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/nn.4593

49140

PHP.eB

POS

Mouse, C57BL6

CNS, gabaergic interneuron

mDLX

FP

3E11 vg/animal

RO

8 weeks

https://doi.org/10.1038/nn.4593

PHP.B

POS

Mouse, C57BL6

CNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nbt.3440

37825

PHP.B

POS

Mouse, C57BL6

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/nbt.3440

37825

PHP.B

POS

Mouse, C57BL6

CNS, all

CAG

FP

2E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nbt.3440

37825

PHP.B

POS

Mouse, GAD2-Cre

CNS, excitatory neurons

CaMKIIa

Sensor jRCaMP1b

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.neuron.2017.04.017

PHP.B

POS

Mouse, GAD2-Cre

CNS, GAD+ neurons

EF1a DIO

Sensor GCaMP6f

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.neuron.2017.04.017

PHP.B

POS

Mouse, SST-Cre

CNS, SST+ neurons

CAG DIO

Sensor GCaMP6f

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.neuron.2017.04.017

PHP.B

POS

Mouse, PV-Cre

CNS, PV+ neurons

CAG DIO

Sensor GCaMP6f

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.neuron.2017.04.017

PHP.B

POS

Mouse, Tac2-Cre

CNS, Tac2+ neurons

hSyn1 DIO

Rescue P2A FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.cell.2018.03.037

PHP.B

POS

Mouse, Tac2-Cre

CNS, Tac2+ neurons

hSyn1 DIO

Rescue P2A FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.cell.2018.03.037

PHP.B

POS

Mouse, Tac2-Cre

CNS, Tac2+ neurons

hSyn1 DIO

Chemogenetic hM3D(Gq)

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.cell.2018.03.037

44361

PHP.B

POS

Mouse, Tac2-Cre

CNS, Tac2+ neurons

hSyn1 DIO

FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.cell.2018.03.037

50459

PHP.B

POS

Mouse, Trim9 -/-

CNS, all

CAG

Rescue

1.5E12 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.celrep.2018.12.055

PHP.B

POS

Mouse, Trim9 -/-

CNS, all

CAG

FP

1.5E12 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.celrep.2018.12.055

PHP.S

POS

Mouse, Chat-Cre

PNS, cardiac ganglia, cholinergic neurons

CAG DIO

FP

3E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-019-09770-1

104058, 104059

PHP.S

POS

Mouse, Chat-Cre

PNS, cardiac ganglia, cholinergic neurons

CAG DIO

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-019-09770-1

127090

PHP.S

POS

Mouse, Chat-Cre

PNS, cardiac ganglia, cholinergic neurons

CAG DIO

Opsin, ChR2(H134R)-FP

1E12 vg/animal

RO

5 weeks

https://doi.org/10.1038/s41467-019-09770-1

PHP.eB

POS

Mouse, Nf1+/-

CNS, catecholaminergic neurons

rTh

FP

1E11 vg/animal

RO

<3 weeks

https://doi.org/10.7554/eLife.48983

133268, 99131, 99114, 99113

PHP.eB

NEG

Mouse, C57BL6

CNS, cortical neurons

hSyn1

Opsin, ChR2(H134R)-FP

5E11 vg/animal

RO

https://doi.org/10.1038/s41592-019-0583-8

PHP.eB

POS

Mouse, C57BL6

CNS, cortical neurons

hSyn1

Opsin, ChRger2

5E11 vg/animal

RO

https://doi.org/10.1038/s41592-019-0583-8

127237

PHP.eB

POS

Mouse, C57BL6

CNS, cortical neurons

hSyn1

Opsin, CoChR

1E11 vg/animal

RO

https://doi.org/10.1038/s41592-019-0583-8

PHP.eB

POS

Mouse, C57BL6

CNS, cortical neurons

hSyn1

Opsin, ChRger2

1E11 vg/animal

RO

https://doi.org/10.1038/s41592-019-0583-8

127237

PHP.eB

POS

Mouse, C57BL6

CNS, excitatory neurons

CaMKIIa

Opsin, CoChR

1E11 vg/animal

RO

https://doi.org/10.1038/s41592-019-0583-8

PHP.eB

POS

Mouse, C57BL6

CNS, excitatory neurons

CaMKIIa

Opsin, ChRger2

1E11 vg/animal

RO

https://doi.org/10.1038/s41592-019-0583-8

127238

PHP.eB

NEG

Mouse, Dat-Cre

CNS, dopaminergic neurons

CAG DIO

Opsin, ChR2(H134R)-FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-019-0583-8

PHP.eB

POS

Mouse, Dat-Cre

CNS, dopaminergic neurons

CAG DIO

Opsin, ChRger2

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-019-0583-8

127239

PHP.eB

NEG

Mouse, C57BL6

CNS, excitatory neurons

CaMKIIa

Opsin, ChR2(H134R)-FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-019-0583-8

PHP.eB

POS

Mouse, C57BL6

CNS, excitatory neurons

CaMKIIa

Opsin, ChRger2

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-019-0583-8

127238

PHP.S

POS

Mouse, C57BL6 aged

PNS, myenteric neurons

hSyn1-tTA TRE

Rescue

3.5E11 vg/animal

RO

2 weeks, 10 weeks

https://doi.org/10.1038/s41593-020-0589-7

99120

PHP.S

POS

Mouse, C57BL6 aged

PNS, myenteric neurons

hSyn1-tTA TRE

Sensor, jRGECO1a

3.5E11 vg/animal

RO

2 weeks, 10 weeks

https://doi.org/10.1038/s41593-020-0589-7

99120

PHP.S

POS

Mouse, C57BL6 aged

PNS, myenteric neurons

hSyn1-tTA TRE

Opsin, ChR2(H134R)-FP

1E11 vg/animal

RO

2 weeks, 10 weeks

https://doi.org/10.1038/s41593-020-0589-7

PHP.S

POS

Mouse, ASO aged

PNS, myenteric neurons

hSyn1-tTA TRE

Rescue

3.5E11 vg/animal

RO

2 weeks, 10 weeks

https://doi.org/10.1038/s41593-020-0589-7

PHP.S

POS

Mouse, ASO aged

PNS, myenteric neurons

hSyn1-tTA TRE

Sensor, jRGECO1a

3.5E11 vg/animal

RO

2 weeks, 10 weeks

https://doi.org/10.1038/s41593-020-0589-7

PHP.S

POS

Mouse, ASO aged

PNS, myenteric neurons

hSyn1-tTA TRE

Opsin, ChR2(H134R)-FP

1E11 vg/animal

RO

2 weeks, 10 weeks

https://doi.org/10.1038/s41593-020-0589-7

PHP.eB

POS

Mouse, FVB/B6

CNS, neurons

hSyn1

shRNA FP

RO

5 weeks

https://doi.org/10.1038/s41586-020-2156-5

PHP.V1

POS

Mouse, C57BL6

CNS, endothelial astrocyte

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

99134

PHP.V1

POS

Mouse, Tek-Cre

CNS, endothelial

CAG DIO

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-020-0799-7

104052

PHP.V1

POS

Mouse, Ai14

CNS, endothelial

Ple261

iCre

3E11 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-020-0799-7

49113

PHP.B

POS

Mouse, C57BL6

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.eB

POS

Mouse, C57BL6

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.C1

POS

Mouse, C57BL6

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.N

POS

Mouse, C57BL6

CNS, neurons

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.N

POS

Mouse, C57BL6

CNS, neurons

CAG

FP

2E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.V1

NEG

Mouse, BALBc

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.N

NEG

Mouse, BALBc

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.B

NEG

Mouse, BALBc

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.V1

POS

Mouse, FVB

CNS, endothelial astrocyte

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.N

POS

Mouse, FVB

CNS, neuron

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.C2

POS

Mouse, C57BL6

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.C3

POS

Mouse, C57BL6

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.C1

POS

Mouse, BALBc

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.C2

POS

Mouse, BALBc

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.C3

POS

Mouse, BALBc

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.V2

POS

Mouse, C57BL6

CNS, endothelial astrocyte

CAG

FP

3E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41592-020-0799-7

104061, 99134

PHP.V2

POS

Mouse, Tek-Cre

CNS, endothelial

CAG DIO

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-020-0799-7

104052

PHP.V2

POS

Mouse, GFAP-Cre

CNS, astrocyte

CAG DIO

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-020-0799-7

104052

PHP.V1

POS

Mouse, C57BL6

CNS, astrocyte

GfABC1D

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-020-0799-7

104053

PHP.eB

POS

Mouse, C57BL6

CNS, astrocyte

GfABC1D

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41592-020-0799-7

104053

PHP.eB

POS

Mouse, C57BL6

CNS, all

CAG

FP

1.5E10 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41467-020-15818-4

37825

PHP.eB

POS

Mouse, C57BL6

CNS, neurons

hSyn1

FP

1E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.celrep.2021.108754

163509

CAP-B10

POS

Mouse, C57BL6

CNS, neuron

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-021-00969-4

104061

PHP.eB

POS

Mouse, C57BL6

CNS, neuron, astrocyte bias, oligodendrocyte

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-021-00969-4

104061

PHP.eB

Marmoset

CNS

CAG

HA-FXN

7E13 vg/kg

femoral vein, cephalic vein, saphenous vein

32 - 42 days

https://doi.org/10.1038/s41593-021-00969-4

CAP-B10

POS

Marmoset

CNS, neuron bias, cortical, sub-cortex, cerebellum, spinal cord, dorsal root ganglia (DRG)

CAG

HA-FXN

7E13 vg/kg

femoral vein, cephalic vein, saphenous vein

32 - 42 days

https://doi.org/10.1038/s41593-021-00969-4

CAP-B22

POS

Marmoset

CNS, cortex, astrocyte bias

CAG

HA-FXN

7E13 vg/kg

femoral vein, cephalic vein, saphenous vein

32 - 42 days

https://doi.org/10.1038/s41593-021-00969-4

PHP.eB

POS

Mouse, C57BL6/J

CNS, retinal neurons, photoreceptors

CAG

FP

1E11 vg/animal

RO

5 weeks

https://doi.org/10.1007/978-3-030-27378-1_18

59462

PHP.eB

POS

Mouse, C57BL6/J

CNS, retinal neurons, photoreceptors

CAG

FP

1E10 vg/animal

Subretinal

5 weeks

https://doi.org/10.1007/978-3-030-27378-1_18

59462

PHP.eB

NEG

Mouse, C57BL6/J

CNS, retinal neurons, photoreceptors

CAG

FP

1E10 vg/animal

Intravitreal

5 weeks

https://doi.org/10.1007/978-3-030-27378-1_18

59462

PHP.eB

POS

Rat, Sprague-Dawley

CNS

CAG

FP

1.2E13 vg/kg

Tail vein

4 weeks

https://doi.org/10.1038/s41434-018-0028-5

PHP.eB

POS

Rat, Sprague-Dawley

CNS

CAG

FP

3.6E13 vg/kg

Tail vein

4 weeks

https://doi.org/10.1038/s41434-018-0028-5

PHP.eB

POS

Rat, Sprague-Dawley

CNS

CAG

FP

1.2E14 vg/kg

Tail vein

4 weeks

https://doi.org/10.1038/s41434-018-0028-5

PHP.eB

POS

Mouse, C57BL/J

CNS, excitatory neurons

CaMKIIa

FP

IV

3 weeks

https://doi.org/10.1038/s41596-019-0148-4

PHP.eB

POS

Mouse, C57BL/J

CNS, inhibitory interneurons

mDLX

FP

IV

3 weeks

https://doi.org/10.1038/s41596-019-0148-4

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes, glutamatergic neurons, GABAergic neurons

CAG-NLS

FP

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes, neurons

CAG-NLS

FP

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

CAP-B10

POS

Mouse, C57BL/6J

CNS, glutamatergic neurons bias, GABAergic neurons, astrocytes

CAG-NLS

FP

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

CAP-B10

POS

Mouse, C57BL/6J

CNS, neurons bias, astrocytes

CAG-NLS

FP

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.V1

POS

Mouse, C57BL/6J

CNS, endothelial vascular cells bias, Myoc+ astrocytes

CAG-NLS

FP

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes (neuronal tropism not analyzed in this assay)

CAG-NLS

FP

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.V1

POS

Mouse, C57BL/6J

CNS, endothelial vascular cells bias, Myoc+ astrocytes

CAG-NLS

FP, RNA barcode

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes (neuronal tropism not analyzed in this assay)

CAG-NLS

FP, RNA barcode

1.5E11vg/animal

RO

3-4 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.eB

POS

Mouse, C57BL/6J

CNS, endothelial vascular cells bias, Myoc- astrocytes

CAG-NLS

FP

1.5E11vg/animal

RO

3 days

https://doi.org/10.3389/fimmu.2021.730825

PHP.eB

POS

Mouse, C57BL/6J

CNS, Myoc- astrocytes bias, glutamatergic neurns, GABAergic neurons, endothelial vascular cells

CAG-NLS

FP

1.5E11vg/animal

RO

25 days

https://doi.org/10.3389/fimmu.2021.730825

PHP.eB

POS

Mouse, C57BL/6J

CNS, Myoc- astrocytes

UBC

FP, RNA barcode

1.5E11 vg/variant (1.05E12/animal)

RO

3 weeks

https://doi.org/10.3389/fimmu.2021.730825

CAP-B10

POS

Mouse, C57BL/6J

CNS, glutamatergic neurons

UBC

FP, RNA barcode

1.5E11 vg/variant (1.05E12/animal)

RO

3 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.V1

POS

Mouse, C57BL/6J

CNS, endothelial vascular cells

UBC

FP, RNA barcode

1.5E11 vg/variant (1.05E12/animal)

RO

3 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.B

POS

Mouse, C57BL/6J

CNS, GABAergic neurons

UBC

FP, RNA barcode

1.5E11 vg/variant (1.05E12/animal)

RO

3 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.C1

NEG

Mouse, C57BL/6J

CNS

UBC

FP, RNA barcode

1.5E11 vg/variant (1.05E12/animal)

RO

3 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.C2

POS

Mouse, C57BL/6J

CNS, Myoc- astrocytes, endothelial vascular cells, and vascular LMCs

UBC

FP, RNA barcode

1.5E11 vg/variant (1.05E12/animal)

RO

3 weeks

https://doi.org/10.3389/fimmu.2021.730825

PHP.B

POS

Mouse, Npc1m1N/m1N

CNS, hippocampus, striatum, cerebelllar molecular cell layer, and vestibular nucleus

EF1a(s)

FP

1.21E12 vg/animal

RO

5.5 weeks

10.26508/lsa.202101040

PHP.B

POS

Mouse, Npc1+/+

CNS, hippocampus, striatum, cerebelllar molecular cell layer, and vestibular nucleus

EF1a(s)

FP

1.21E12 vg/animal

RO

5.5 weeks

10.26508/lsa.202101040

PHP.B

POS

Mouse, Npc1m1N/m1N

CNS, cerebrum and cerebellum

EF1a(s)

Rescue

1.43E12 vg/animal

RO

5.5 weeks

10.26508/lsa.202101040

PHP.eB

POS

Mouse, 5XFAD

CNS

hSyn1

CRISPR, SaCas9, sgRNA

1E13 vg/animal

RO

3 months

10.1038/s41551-021-00759-0

PHP.eB

POS

Mouse, 5XFAD

CNS, hippocampus, cortex, medulla, and brain stem

hSyn1

CRISPR, SaCas9, sgRNA

1E13 vg/animal

RO

3 months

10.1038/s41551-021-00759-0

PHP.eB

POS

Mouse, Aldh1l1-Cre/ERT2

CNS, astrocyte, kidney, liver

CAG-FLEx

FP, Rescue, iBARK-mCherry

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.neuron.2021.05.023

117693

PHP.eB

POS

Mouse, Aldh1l1-Cre/ERT2

CNS, astrocyte, kidney, liver

CAG-FLEx

FP, Rescue, iBARK D110A-mCherry

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.neuron.2021.05.023

117694

PHP.B

POS

Mouse, C57BL/6J

CNS, cortial, striatal, and hippocampal neurons

CAG

FP

1E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1093/braincomms/fcab105

PHP.B

NEG

Mouse, CBA/Ca

N/A

CAG

FP

1E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1093/braincomms/fcab105

PHP.eB

POS

Mouse, C57BL/6J

Liver and CNS, cortex, striatum, hippocampus, cerebellum, brainstem

CAG

FP

1E11 vg/animal

Tail vein

2 hours

https://doi.org/10.1093/braincomms/fcab105

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortex, pyramidal tract (PT) neurons in L5 layer

mscRE4-pBCmin

FP

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortex, pyramidal tract (PT) neurons in L5 layer bias

mscRE4-pBCmin

FP

1-4E10 vg/site

Intracranial (VISp)

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortex, intratelencephalic (IT) neurons in L5 layer bias

mscRE16-pBCmin

FP

1-4E9 vg/site

Intracranial (VISp)

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortex, pyramidal tract (PT) neurons in L5 layer

3x Core mscRE4-pCMVmin

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai65F

CNS, cortex, pyramidal tract (PT) neurons in L5, dense labeling

mscRE4-pBCmin

Recombinase, FlpO

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai14

CNS, cortex nonspecific

mscRE4-pBCmin

Recombinase, dgCre

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai14

CNS, cortex exitatory neurons in L5 and L6

mscRE4-pBCmin

Recombinase, iCre

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai63

CNS, cortex, neurons in L5, sparse labeling

mscRE4-pBCmin

Inducer, tTA2

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai65F

CNS, cortex, pyramidal tract (PT) neurons in L5, dense labeling

mscRE4-pBCmin

Recombinase, FlpO

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai65F

CNS, cortex, corticothamic (CT) neurons in L6 bias, sparse labeling

mscRE10-pBCmin

Recombinase, FlpO

1E10 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai65F

CNS, cortex, CT, IT, and PT neurons in L5 and L6

mscRE13-pBCmin

Recombinase, FlpO

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai65F

CNS, cortex, intratelencephalic (IT) neurons in L5 bias

mscRE16-pBCmin

Recombinase, FlpO

1E11 vg/animal

RO

2-3 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai65F/wt; Ai140/wt (double reporter)

CNS, cortex, intratelencephalic (IT) neurons in L5

mscRE16-pBCmin

Recombinase, FlpO

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai65F/wt; Ai140/wt (double reporter)

CNS, cortex, pyramidal tract (PT) neurons in L5

mscRE4-pBCmin

Recombinase, iCre

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, neurons

pSyn

Recombinase, Cre

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, neurons

pSyn

Recombinase, FlpO

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, neurons

pSyn

Recombinase, oNigri

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, pan-neuronal

pSyn

Recombinase, Cre

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, pan-neuronal

pSyn

Recombinase, FlpO

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, pan-neuronal

pSyn

Recombinase, oNigri

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, distinct neuronal subclasses

hl56i

Recombinase, iCre-4X2C

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, distinct neuronal subclasses

mscRE4

Recombinase, FlpO

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Mouse, Ai213 (triple-recombinase reporter)

CNS, cortex, distinct neuronal subclasses

mscRE16

Recombinase, oNigri

1E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.eB

POS

Human, neocortical slice culture

CNS, cortex, sparse labeling L2-L6

mscRE4

FP, Recombinase, FlpO

direct application to slice

https://doi.org/10.1016/j.neuron.2021.03.011

PHP.S

POS

Mouse, NAMPT:MPZ-Cre

PNS, DRG neurons

hSyn1

FP

Intrathecal

2 weeks

https://doi.org/10.1523/JNEUROSCI.3304-17.2018

50465

PHP.S

POS

Mouse, C57BL/6J

CNS, cerebellum vestibular ganglion neurons

CAG

FP

3.4E11 vg/animal

posterior semicircular canal

2 weeks

https://doi.org/10.7554/eLife.44964

59462

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1-H2B

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163509

PHP.eB

POS

Mouse, C57BL/6J

CNS, telencephalic interneurons

hDLXI56i-minBG

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163493

PHP.eB

POS

Mouse, C57BL/6J

CNS, SLC17a7+ neurons, excitatory IT neurons in L56 bias

eHGT_078h-minBG

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163495

PHP.eB

POS

Mouse, C57BL/6J

CNS, RORB+ neurons in L4, excitatory IT neurons in L56

eHGT_058h-minBG

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163494

PHP.eB

POS

Mouse, C57BL/6J

CNS, LAMP5+ inhibitory neurons

eHGT_019h-minBG

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163496

PHP.eB

POS

Mouse, C57BL/6J

CNS, SST+ neuronal bias, VIP+ neurons

eHGT_017h-minBG

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163497

PHP.eB

POS

Mouse, C57BL/6J

CNS, PVALB+ neurons

eHGT_128h-minRho

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163498

PHP.eB

POS

Mouse, C57BL/6J

CNS, PVALB+ neurons

eHGT_079h-minRho

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163501

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortex, PVALB+ neurons, midbrain structures, deep cerebellar nuclei, and main olfactory bulb

eHGT_082h-minRho

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163502

PHP.eB

POS

Mouse, C57BL/6J

CNS, PVALB+ neurons

eHGT_140h-minRho

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163503

PHP.eB

POS

Mouse, C57BL/6J

CNS, PVALB+ neurons

eHGT_359h-minRho

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163504

PHP.eB

POS

Mouse, C57BL/6J

CNS, cortex, PVALB+ neurons bias, SST+ neurons, cerebellar Purkinje cells, mid/hindbrain nuclei, hippocampus, and main olfactory bulb neurons

eHGT_023h-minBG

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163499

PHP.eB

POS

Mouse, C57BL/6J

CNS, PVALB+ neurons bias, SST+ neurons

eHGT_064h-minBG

FP

2-3E11 vg/animal

RO

3-4 weeks

10.1016/j.celrep.2021.108754

163500

PHP.eB

POS

NHP, Macaca mulatta

CNS, PVALB+ neurons

eHGT_079h_minRho

FP

1-2E11 vg/site

Intracranial (occipital)

51-113 days

10.1016/j.celrep.2021.108754

163501

PHP.eB

POS

NHP, Macaca nemestrina

CNS, PVALB+ neurons

eHGT_082h-minRho

FP

1-2E11 vg/site

Intracranial (occipital)

51-113 days

10.1016/j.celrep.2021.108754

163502

PHP.eB

POS

NHP, Macaca mulatta

CNS, PVALB+ neurons

eHGT_128h-minRho

FP

1-2E11 vg/site

Intracranial (occipital)

51-113 days

10.1016/j.celrep.2021.108754

163498

PHP.eB

POS

NHP, Macaca nemestrina

CNS, PVALB+ neurons

eHGT_359h-minRho

FP

1-2E11 vg/site

Intracranial (occipital)

51-113 days

10.1016/j.celrep.2021.108754

163504

PHP.eB

POS

NHP, Macaca mulatta

CNS, PVALB+ neurons

eHGT_140h-minRho

FP

1-2E11 vg/site

Intracranial (occipital)

51-113 days

10.1016/j.celrep.2021.108754

163503

PHP.eB

POS

NHP, Macaca mulatta

CNS, PVALB+ neurons

eHGT_140h-minRho

FP

1-2E11 vg/site

Intracranial (temporal)

51-113 days

10.1016/j.celrep.2021.108754

163503

PHP.eB

POS

NHP, Macaca nemestrina

CNS, PVALB+ neurons

eHGT_140h-minRho

FP

1-2E11 vg/site

Intracranial (somatosensory)

51-113 days

10.1016/j.celrep.2021.108754

163503

PHP.eB

POS

NHP, Macaca nemestrina

CNS, PVALB+ neurons

eHGT_140h-minRho

FP

1-2E11 vg/site

Intracranial (motor)

51-113 days

10.1016/j.celrep.2021.108754

163503

PHP.eB

POS

NHP, Macaca nemestrina, temporal cortex brain slice culture

CNS, L2–L6 excitatory neurons

eHGT_078m-minBG

FP

2-3E10 vg/slice

direct application to slice

1-2 weeks

10.1016/j.celrep.2021.108754

163508

PHP.eB

POS

NHP, Macaca nemestrina, temporal cortex brain slice culture

CNS, L3–L5 pyramidal neurons

eHGT_058h-minBG

FP

2-3E10 vg/slice

direct application to slice

1-2 weeks

10.1016/j.celrep.2021.108754

163494

PHP.eB

POS

NHP, Macaca nemestrina, temporal cortex brain slice culture

CNS, GAD1+ GABAergic neurons

DLX2.0_minBG

FP

2-3E10 vg/slice

direct application to slice

1-2 weeks

10.1016/j.celrep.2021.108754

163505

PHP.eB

POS

NHP, Macaca nemestrina, temporal cortex brain slice culture

CNS, GAD1+ and PVALB+ low specificity

eHGT_079h_minRho

FP

2-3E10 vg/slice

direct application to slice

1-2 weeks

10.1016/j.celrep.2021.108754

163501

PHP.eB

POS

NHP, Macaca nemestrina, temporal cortex brain slice culture

CNS, GAD1+ and PVALB+ low specificity

eHGT_082h-minRho

FP

2-3E10 vg/slice

direct application to slice

1-2 weeks

10.1016/j.celrep.2021.108754

163502

PHP.eB

POS

NHP, Macaca nemestrina, temporal cortex brain slice culture

CNS, GAD1+ and PVALB+ low specificity

eHGT_128h-minRho

FP

2-3E10 vg/slice

direct application to slice

1-2 weeks

10.1016/j.celrep.2021.108754

163498

PHP.eB

POS

NHP, Macaca nemestrina, temporal cortex brainslice culture

CNS, GAD1+ and PVALB+ low specificity

eHGT_140h-minRho

FP

2-3E10 vg/slice

direct application to slice

1-2 weeks

10.1016/j.celrep.2021.108754

163503

PHP.eB

POS

Human, temportal cortex brain slice culture

CNS, GAD1+ inhibitory neurons

hDLXI56i-minBG

FP

2-3E10 vg/slice

direct application to slice

8, 13, 28, and 69 days

10.1016/j.celrep.2021.108754

163493

PHP.eB

POS

Human, temportal cortex brain slice culture

CNS, GAD1+ inhibitory neurons

DLX2.0_minBG

FP

2-3E10 vg/slice

direct application to slice

7, 7, 14, and 34 days

10.1016/j.celrep.2021.108754

163505

PHP.eB

POS

Mouse, Ai14

CNS, cortex

EF1a

Recombinase, Cre

4-8E10 vg/animal

ICV

2 weeks

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Ai14

CNS, cortex

EF1a

Recombinase, Cre

--

RO

2 weeks

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Ai66R

CNS, cortex

EF1a

Recombinase, CDreV

4-8E10 vg/animal

ICV

2 weeks

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Ai66R

CNS, cortex

Syn

Recombinase, NDreV

4-8E10 vg/animal

ICV

2 weeks

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Ai75

CNS, cortex

EF1a

Recombinase, iCreV

4-8E10 vg/animal

ICV

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Ai65F

CNS, cortex

EF1a

Recombinase, iFlpV

4-8E10 vg/animal

ICV

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Rbp4-Cre

CNS, cortex

EF1a, FSF-FLEX

FP

1-2E10 vg/animal

Intracranial (cortex)

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Rbp4-Cre

CNS, cortex

EF1a

Recombinase, iFlpV

1-2E10 vg/animal

Intracranial (cortex)

https://doi.org/10.1038/s41592-020-0774-3

PHP.eB

POS

Mouse, Sst-IRES-FlpO x Ai65

CNS, cortex, somatostatin-positive inhibitory interneurons

EF1a

Recombinase, iCreV

--

RO

https://doi.org/10.1038/s41592-020-0774-3

Cu63labeled-PHP.eB

POS

Mouse, C57BL/6

CNS

CAG

FP

1.5E10 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41467-020-15818-4

PHP.eB

POS

Mouse, C57BL/6

CNS

CAG

FP

1.5E10 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41467-020-15818-4

37825

Cu63labeled-PHP.eB

POS

Mouse, C57BL/6

CNS and spleen

CAG

FP

1.5E10 vg/animal

Tail vein

4 hours

https://doi.org/10.1038/s41467-020-15818-4

Cu63labeled-PHP.eB

POS

Mouse, C57BL/6

CNS bias and spleen

CAG

FP

1.5E10 vg/animal

Tail vein

21 hours

https://doi.org/10.1038/s41467-020-15818-4

PHP.eB

POS

Mouse, C57BL/6

CNS, neurons

hSyn1

FP

3E11 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.eB

POS

Mouse, C57BL/6

CNS, astrocytes

GFAP

FP

3E11 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41596-018-0097-3

104053

PHP.eB

POS

Mouse, C57BL/6

CNS, oligodendrocyte

MBP

FP

3E11 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41596-018-0097-3

104054

PHP.eB

POS

Mouse, C57BL/6

CNS, all

CAG

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.eB

POS

Mouse, C57BL/6

CNS, neurons

CAG miR-204TS

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.eB

POS

Mouse, C57BL/6

CNS, astrocytes

CAG miR-708TS

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.S

POS

Mouse, TH-IRES-Cre

PNS, paravertebral ganglia

CAG DIO

FP

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41596-018-0097-3

104058

PHP.S

POS

Mouse, TH-IRES-Cre

PNS, paravertebral ganglia

hSyn1

FP

1E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41596-018-0097-3

99135

PHP.S

POS

Mouse, TRPV1-IRES-Cre

PNS, nodose ganglion

CAG DIO

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

104052

PHP.S

POS

Mouse, TRPV1-IRES-Cre

PNS, DRG

CAG DIO

FP

3E12 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41596-018-0097-3

104058, 104059

PHP.S

POS

Mouse, C57BL/6

PNS, duodenum, myenteric plexus, submucosal plexus

mTH

FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.S

POS

Mouse, C57BL/6

PNS, duodenum, myenteric plexus, submucosal plexus

hSyn

FP

5E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

104060

PHP.S

POS

Mouse, C57BL/6

Heart

CAG

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41596-018-0097-3

104061

PHP.S

POS

Mouse, C57BL/6

Heart, cardiac muscle

CAG

FP

1E12 vg/animal

RO

11 days

https://doi.org/10.1038/s41596-018-0097-3

99134, 99123, 99122

PHP.S

POS

Mouse, TRPV1-IRES-Cre

PNS, cardiac nerves

CAG DIO

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

99133, 104058, 104059

PHP.S

POS

Mouse, ChAT-IRES-Cre

PNS, cardiac ganglion

Ef1a DIO

ChR2, FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

20298

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

99134

PHP.B

POS

Mouse, FVB/NCrl

CNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

99134

PHP.B

POS

Mouse, 129S1/SvlmJ

CNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

99134

PHP.B

NEG

Mouse, BALBcJ

CNS, all

CAG

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

99134

PHP.eB

POS

Mouse, 129T2/SvEmsJ

CNS, all

CAG

FP

3E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.eB

POS

Rat, Fischer

CNS, all

CAG

FP

3E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.eB

POS

Rat, Long-Evans

CNS, neurons, liver detarget

CMV-hSyn1 miR122TS

Sensor, GCaMP6f

1E13 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.B

POS

Mouse, FVB/NCrl

CNS, neurons

CaMKIIa

Sensor, CaMPARI

3E11 vg/animal

RO

2 weeks

https://doi.org/10.1038/s41596-018-0097-3

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

Sensor, SPOTlight

3E11 vg/animal

RO

2 weeks

https://doi.org/10.1126/science.abe1931

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1126/science.abe1931

PHP.S

POS

Mouse, Mrgpra3Cre; NmbrCre; RosaTdtf/+

PNS, spinal neurons

CAG DIO

Opsin, ChR2, FP

7.5E10 vg/animal

Intrathecal

3 weeks

https://doi.org/10.1016/j.neuron.2021.12.007

PHP.B

POS

Rat, Sprague-Dawley, neonate

CNS, all

CBA

FP

1.9E12 vg/animal

Facial vein

4 weeks

https://doi.org/10.3389/fnmol.2016.00116

PHP.B

POS

Rat, Sprague-Dawley

CNS, neurons

Syn

FP

3.8E13 vg/kg

RO or Tail vein

4 weeks

https://doi.org/10.3389/fnmol.2016.00116

PHP.B

POS

Rat, Sprague-Dawley, neonate

CNS, all

CBA

Disease model

1.6E12 vg/animal

Facial vein

<10 days

https://doi.org/10.3389/fnmol.2016.00116

PHP.B

POS

Rat, Sprague-Dawley

CNS, all

CBA

Disease model

3E13 vg/kg

RO or Tail vein

2 weeks

https://doi.org/10.3389/fnmol.2016.00116

PHP.B

POS

Mouse, FRMD7tm1a(KOMP)Wtsi

CNS, all

EF1a

Sensor, GCaMP6s

1.7E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/nn.4566

PHP.B

POS

Mouse, BChE KO

CNS, all

Rescue

1E13 vg/animal

Tail vein

3 weeks

https://doi.org/10.3390/molecules22071145

PHP.B

POS

Mouse, C57BL/6J

CNS, purkinje neuron

L7-6

FP

3E12 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2017.07.006

PHP.B

POS

Mouse, AβPPswe/PS-1

CNS, hippocampus

IE4/5

Rescue

Intracranial (hippocampus)

2.5 weeks

https://doi.org/10.1093/brain/awx272

PHP.B

POS

Mouse, AβPPswe/PS-1

CNS, hippocampus

IE4/5

FP

Intracranial (hippocampus)

2.5 weeks

https://doi.org/10.1093/brain/awx272

PHP.B

POS

Mouse, C57Bl6/J

CNS, all, DRG, Sympathetic ganglia

CBA

FP

2E12 vg/animal

Tail vein

3-5 weeks

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, neonate

CNS, all, Spinal cord

CBA

FP

1.5E11 vg/animal

Facial vein

3 weeks

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, Ai9

CNS, all

CBA

Recombinase, Cre

1E9 - 1E12 vg/animal

Tail vein

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, NeuroD6-Cre

CNS, neurons cortex hippocampus

CBA FLEX

FP

2E12 vg/animal

Tail vein

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, PV-Cre

CNS, gabaergic interneuron

CBA FLEX

FP

2E12 vg/animal

Tail vein

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, Dat-Cre

CNS, dopaminergic neurons

CBA FLEX

FP

2E12 vg/animal

Tail vein

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, Olig2-Cre

CNS, oligodendrocyte

CBA FLEX

FP

2E12 vg/animal

Tail vein

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, PV-Cre

CNS, gabaergic interneuron

Syn FLEX

Chemogenetic DREADDM4, FP

2E12 vg/animal

Tail vein

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, Tsc1f/f

CNS, all

CBA

Recombinase, Cre

2E12 vg/animal

Tail vein

1 week

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, Tsc1f/f

CNS, all

CBA

Recombinase, Cre

1E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, A53T-SCNA

CNS, all

EF1a

Rescue, FP

2E12 vg/animal

Tail vein

3 - 5 months

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, C57Bl6/J

CNS, all, reduced periphery

CBA

FP

2E12 vg/animal

Carotid artery

3 weeks

https://doi.org/10.1016/j.ymthe.2017.08.004

PHP.B

POS

Mouse, C57BL/6J

CNS, all

FP

5E13 vg/kg

https://doi.org/10.1016/j.ymthe.2018.01.018

PHP.B

NEG

Mouse, BALBcJ

CNS, all

FP

5E13 vg/kg

https://doi.org/10.1016/j.ymthe.2018.01.018

PHP.B

NEG

NHP, rhesus macaque

CNS, all

FP

7.5E13 vg/kg

5 days

https://doi.org/10.1016/j.ymthe.2018.01.018

PHP.B

NEG

NHP, rhesus macaque

CNS, all

FP

2E13 vg/kg

3 weeks

https://doi.org/10.1016/j.ymthe.2018.01.018

PHP.B

POS

Mouse

CNS, C57Bl/6J

Sensor, GCaMP6s

RO

https://doi.org/10.1038/nbt.4034

PHP.B

NEG

NHP, marmoset

CNS, all

CBh

FP

5E13 vg/kg

femoral vein

6 weeks

https://doi.org/10.1016/j.neulet.2017.11.049

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBh

FP

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.neulet.2017.11.049

PHP.B

POS

Mouse, Rho+/P23H

Retina

CBA

FP

1E12 vg/animal

Intravitreal

2 weels

https://doi.org/10.1093/hmg/ddx438

PHP.B

POS

Mouse, Rho+/P23H

Retina

TetO

CRISPR, SpCas9-VQR

1E12 vg/animal

Intravitreal

2 weels

https://doi.org/10.1093/hmg/ddx438

PHP.B

POS

Mouse, Rho+/P23H

Retina

hRho

CRISPR, sgRNA, Inducer

1E12 vg/animal

Intravitreal

2 weels

https://doi.org/10.1093/hmg/ddx438

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBA self complimentary

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41434-018-0005-z

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBA self complimentary

FP

2.5E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41434-018-0005-z

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn self complimentary

FP

2E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41434-018-0005-z

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn self complimentary

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41434-018-0005-z

PHP.B

POS

Mouse, Gja10-Cre

Retina

Ef1a DIO

Rescue

3E14 vg/kg

RO

4-5 weeks

https://doi.org/10.1016/j.neuron.2018.06.001

PHP.B

POS

Mouse, Gja10Cre × PV-Flp × Flp-GFP-reporter

Retina

Ef1a DIO

Rescue

3E14 vg/kg

RO

4-5 weeks

https://doi.org/10.1016/j.neuron.2018.06.001

PHP.B

POS

Mouse, C57BL/6J

Spinal cord

hSyn

Rescue

1E12 vg/animal

Tail vein

8 weeks

https://doi.org/10.1016/j.cell.2018.06.005

PHP.B

POS

Mouse, C57BL/6J

Spinal cord

hSyn

FP

1E12 vg/animal

Tail vein

8 weeks

https://doi.org/10.1016/j.cell.2018.06.005

PHP.B

POS

Mouse, Chat-Cre

Spinal cord

hSyn FLEX

Rescue

1E12 vg/animal

Tail vein

8 weeks

https://doi.org/10.1016/j.cell.2018.06.005

PHP.B

POS

Mouse, Vglut2-Cre

Spinal cord

hSyn FLEX

Rescue

1E12 vg/animal

Tail vein

8 weeks

https://doi.org/10.1016/j.cell.2018.06.005

PHP.B

POS

Mouse, Vgat-Cre

Spinal cord

hSyn FLEX

Rescue

1E12 vg/animal

Tail vein

8 weeks

https://doi.org/10.1016/j.cell.2018.06.005

PHP.B

POS

Mouse

Cochlea neurons

hSyn

Opsin, Chronos

1-2E9 vg/animal

Cochlea

4-12 weeks

https://doi.org/10.15252/embj.201899649

PHP.B

POS

Mouse, neonate

Cochlea neurons

hSyn

Opsin, Chronos

1-2E9 vg/animal

Cochlea

4-12 weeks

https://doi.org/10.15252/embj.201899649

PHP.eB

POS

Mouse, GFAP-mCAT

CNS, astrocytes

GFAP

FP

5E10 vg/animal

RO

3 weeks

https://doi.org/10.1038/s42255-018-0031-6

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Sensor, GCaMP6s

6E11 vg/animal

Tail vein

4-8 weeks

https://doi.org/10.1117/1.NPh.6.2.025014

PHP.eB

POS

Mouse, fos-cre −/−

CNS, neurons

hSyn

Sensor, GCaMP6s

6E11 vg/animal

Tail vein

4-8 weeks

https://doi.org/10.1117/1.NPh.6.2.025014

PHP.eB

NEG

Mouse, C57BL/6J

Inner ear

CAG

FP

3.6E9 vg/animal

Round window membrane

https://doi.org/10.1038/s41467-019-11687-8

PHP.eB

POS

Mouse, C57BL/6J aged

CNS, oligodendrocyte

CMV

CRISPR, SpCas9

5E11 vg/animal

Tail vein

4 weeks

https://doi.org/10.1038/s41586-019-1484-9

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, oligodendrocyte

CMV

CRISPR, SpCas9

5E10 vg/animal

Tail vein

4 weeks

https://doi.org/10.1038/s41586-019-1484-9

PHP.eB

POS

Mouse, Sim1-Cre

CNS, neurons

hSyn FLEX

Recombinase, FLPo

RO

https://doi.org/10.1016/j.cell.2019.07.042

122503

PHP.eB

POS

Mouse, Sim1-Cre

CNS, neurons

CAG FRT

FP

RO

https://doi.org/10.1016/j.cell.2019.07.042

122504

PHP.eB

POS

Mouse, AKR/J

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

POS

Mouse, C57L/J

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

POS

Mouse, DBA/J

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

NEG

Mouse, BALB/cJ

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

POS

Mouse, FVB/NJ

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

POS

Mouse, LP/J

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

POS

Mouse, MOLF/EiJ

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

NEG

Mouse, CAST/EiJ

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

NEG

Mouse, CBA/J

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

NEG

Mouse, NOD/ShiLtJ

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

NEG

Mouse, NZB/B1NJ

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

NEG

Mouse, PWK/PhJ

CNS, all

CAG

FP

1E11 vg/animal

RO

https://doi.org/10.1371/journal.pone.0225206

PHP.eB

POS

Mouse, C57BL6 aged

CNS, all

CAG

FP

4E11 vg/animal

6-12 months

https://doi.org/10.1186/s13059-019-1866-1

PHP.eB

POS

Mouse, C57BL6 aged

CNS, all

CAG

Rescue, FP

4E11 vg/animal

6-12 months

https://doi.org/10.1186/s13059-019-1866-1

PHP.eB

POS

Mouse, C57BL/6N or 6J

CNS, neurons

NSE

FP

6.4E11 vg/animal

RO

1 month

https://doi.org/10.1038/s41596-019-0240-9

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBh

Rescue, FP

1-3E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.nbd.2018.10.014

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBA self complimentary

FP

1E12 vg/animal

Tail vein

3 weeks

10.3791/58960

PHP.B

POS

Mouse, GAAKO

CNS, all

CMV/CB

Rescue

5E12 vg/kg

RO

14 weeks

https://doi.org/10.1016/j.omtm.2019.01.006

PHP.B

POS

Mongolian gerbil

Inner ear nearons

hSyn

Opsin, ChR2 CatCH

1E10 vg/animal

cochlea spiral ganglion

4 weeks

https://doi.org/10.1038/s41467-019-09980-7

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

NEG

Mouse, BALBcJ

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

NEG

Mouse, Ly6a-KO

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

POS

Mouse, 129S1/SvlmJ

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

POS

Mouse, DBA/2J

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

POS

Mouse, FVB/NJ

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

NEG

Mouse, C3H/HeJ

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

NEG

Mouse, CBA/J

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

NEG

Mouse, A/J

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.ymthe.2019.02.013

PHP.B

POS

Mouse, C57BL/J

CNS, astrocytes

GFAP

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1007/s12035-018-1366-4

PHP.B

POS

Mouse, C57BL/J

CNS, neurons

rNSE

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1007/s12035-018-1366-4

PHP.B

NEG

Rat, Sprague-Dawley

CNS

FP

4-5E13 vg/kg

3 weeks

https://doi.org/10.1007/s12035-018-1366-4

PHP.B

NEG

Mouse

Inner ear

CMV

FP

1E7 vg/animal

Round window membrane

3 weeks

https://doi.org/10.1016/j.omtm.2019.01.002

PHP.B

POS

Mouse, C57BL/6J neonate

Inner ear

CBA

FP

5E10 vg/animal

Round window membrane

5 days

https://doi.org/10.1016/j.omtm.2018.11.003

PHP.B

POS

Mouse, CD1 neonate

Inner ear

CBA

FP

5E10 vg/animal

Round window membrane

5 days

https://doi.org/10.1016/j.omtm.2018.11.003

PHP.B

POS

Mouse, Crln1−/− neonate

Inner ear

CBA

Rescue

7.4E10 vg/animal

Round window membrane

4 weeks

https://doi.org/10.1016/j.omtm.2018.11.003

PHP.B

POS

Mouse, Crln1−/− neonate

Inner ear

CBA

Rescue

1.8E11 vg/animal

Round window membrane

4 weeks

https://doi.org/10.1016/j.omtm.2018.11.003

PHP.B

POS

Mouse, C57BL/6J

Retina

CBA

FP

2.1E9 vg/animal

subretinal

8 days

https://doi.org/10.1016/j.omtm.2018.11.003

PHP.B

NHP, cynologous monkey

Inner ear

CBA

FP

3E11 vg/animal

Round window membrane

7 weeks

https://doi.org/10.1016/j.omtm.2018.11.003

PHP.B

POS

Mouse, C57BL/6J

PNS, sciatic nerve

CMV

FP

2E11 vg/animal

Tail vein

5 weeks

https://doi.org/10.1016/j.neulet.2019.05.010

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

3E10 vg/animal

jugular vein

https://doi.org/10.1016/j.ymthe.2019.07.017

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

3E10 vg/animal

Carotid artery

https://doi.org/10.1016/j.ymthe.2019.07.017

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

3E10 vg/animal

lateral ventricle

https://doi.org/10.1016/j.ymthe.2019.07.017

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

3E10 vg/animal

intrathecal, cisterna magna

https://doi.org/10.1016/j.ymthe.2019.07.017

PHP.B

NEG

NHP, rhesus macaque juvenile

CNS, all

CAG

FP

1E12 vg/kg

Carotid artery

https://doi.org/10.1016/j.ymthe.2019.07.017

PHP.B

NEG

NHP, rhesus macaque juvenile

CNS, all

CAG

FP

1E12 vg/kg

intrathecal, cisterna magna

https://doi.org/10.1016/j.ymthe.2019.07.017

PHP.eB

POS

Mouse, C3H/He-C57BL/6 hybrid

CNS, all, Retina

CAG

FP

3.3E9 vg/animal

Tail vein

3 weeks

doi:10.7150/thno.42611

PHP.eB

POS

Mouse, Meg+/+, 129/svJ background

CNS, all

CAG

FP

5E10 vg/animal

Tail vein

3 weeks

https://doi.org/10.1093/braincomms/fcaa135

37825

PHP.eB

POS

Mouse, Meg+/-, 129/svJ background

CNS, all

CAG

FP

5E10 vg/animal

Tail vein

3 weeks

https://doi.org/10.1093/braincomms/fcaa135

37825

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

EF1a

Opsin, LINuS

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.bbrc.2019.11.023

PHP.eB

POS

Mouse, Fah−/−/Rag2−/−/Il2rg−/− (FRG)

CNS, all

CMV

FP

3.3E9 vg/animal

Tail vein

7 days

https://doi.org/10.1089/hum.2019.264

PHP.B

POS

Mouse, B6/C3H neonate

CNS, all

CAG

FP

1.5E8 vg/site

ICV

30 days

https://doi.org/10.1186/s13024-020-00361-z

PHP.eB

POS

Mouse, B6/C3H neonate

CNS, all

CAG

FP

3.6E8 vg/site

ICV

30 days

https://doi.org/10.1186/s13024-020-00361-z

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CBA-iMecp2

Rescue

1E11 vg/animal

Tail vein

up to 15 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CBA-iMecp2

Rescue

1E12 vg/animal

Tail vein

up to 15 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

NEG

Mouse, Mecp2-/y

CNS, all

CBA-iMecp2

Rescue

1E9 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2-/y

CNS, all

CBA-iMecp2

Rescue

1E10 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2-/y

CNS, all

CBA-iMecp2

Rescue

1E11 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2-/y

CNS, all

CBA-iMecp2

Rescue

1E12 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

NEG

Mouse, Mecp2-/y

CNS, all

CBA

FP

1E9 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2-/y

CNS, all

CBA

FP

1E10 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2-/y

CNS, all

CBA

FP

1E11 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2-/y

CNS, all

CBA

FP

1E12 vg/animal

Tail vein

up to 12 weeks

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2+/-

CNS, all

CBA-iMecp2

Rescue

1E11 vg/animal

Tail vein

up to 15 months

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, Mecp2+/-

CNS, all

CBA

FP

1E11 vg/animal

Tail vein

up to 15 months

https://doi.org/10.7554/eLife.52629

PHP.eB

POS

Mouse, C57BL/6J

CNS, spinal cord sciatic neurons

Syn

Rescue, FP

6E11 vg/animal

Tail vein

3 days or 4 weeks

https://doi.org/10.1172/JCI125771

PHP.eB

POS

Mouse, C57BL/6J

CNS, spinal cord sciatic neurons

Syn

FP

6E11 vg/animal

Tail vein

3 days or 4 weeks

https://doi.org/10.1172/JCI125771

PHP.eB

POS

Mouse, C57BL/6J

CNS, striatum astrocytes

GFAP

CRISPR, CasRx, sgRNA

1-3E10 vg/site

Intracranial (striatum)

1 week, 1 month, 3 months

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, C57BL/6J

CNS, striatum astrocytes

GFAP

CRISPR, CasRx

1-3E10 vg/site

Intracranial (striatum)

1 week, 1 month, 3 months

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, C57BL/6J

CNS, striatum astrocytes

GFAP

FP

1-3E10 vg/site

Intracranial (striatum)

1 week, 1 month, 3 months

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, C57BL/6J

Retina, astrocytes

GFAP

CRISPR, CasRx, sgRNA

1E10 vg/site

subretinal

2-3 weeks

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, C57BL/6J

Retina, astrocytes

GFAP

CRISPR, CasRx

1E10 vg/site

subretinal

2-3 weeks

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, C57BL/6J

Retina, astrocytes

GFAP

FP

1E10 vg/site

subretinal

2-3 weeks

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, Ai9

Retina, astrocytes

GFAP

CRISPR, CasRx, sgRNA

1E10 vg/site

subretinal

2-3 weeks, 1 month

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, Ai9

Retina, astrocytes

GFAP

CRISPR, CasRx

1E10 vg/site

subretinal

2-3 weeks, 1 month

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, Ai9

Retina, astrocytes

GFAP

FP

1E10 vg/site

subretinal

2-3 weeks, 1 month

https://doi.org/10.1016/j.cell.2020.03.024

PHP.eB

POS

Mouse, Hdac1 cKO aged

CNS, neurons

shRNA, FP

Intracranial (hippocampus)

3 weeks

https://doi.org/10.1038/s41467-020-16361-y

PHP.eB

NEG

Mouse, C57BL/6J neonate

CNS, neurons

Syn

Sensor, GCaMP6s

8E10 vg/site

transverse sinus

5 days - 3 weeks

https://doi.org/10.7554/eLife.53639

100843

PHP.eB

POS

Mouse

CNS, neurons, retina

CAG FLEX

Inducer, tTA2

RO

3 weeks

DOI: 10.1126/science.aaz5887

PHP.eB

POS

Mouse, CaMKIIa-Cre

CNS, neurons

hSyn DIO

FP

1.3E11 vg/animal

RO

3 weeks

https://doi.org/10.3389/fncel.2020.00145

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons, spinal cord

LAP1

FP

4E11 vg/animal

RO

30 days, 190 days

https://doi.org/10.1016/j.omtm.2020.04.004

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons, spinal cord

LAP2

FP

4E11 vg/animal

RO

30 days, 190 days

https://doi.org/10.1016/j.omtm.2020.04.004

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons, spinal cord

LAP1_2

FP

4E11 vg/animal

RO

30 days, 190 days

https://doi.org/10.1016/j.omtm.2020.04.004

PHP.eB

POS

Mouse, C57BL/6J

CNS, all, spinal cord

EF1a

FP

4E11 vg/animal

RO

30 days, 190 days

https://doi.org/10.1016/j.omtm.2020.04.004

PHP.eB

POS

Mouse, floxed-dCas9-VPRVPR/+/Vgat-CreCre/+/Scn1aRX/+

CNS, parvalbumin gabaergic neurons

4x U6

CRISPRa, sgRNA

1.8E11 vg/animal

Tail vein

8 weeks

https://doi.org/10.1016/j.nbd.2020.104954

43860

PHP.eB

POS

Mouse, Klb-CRE

CNS, hypothalamus

CAG FLEX

FP

RO

4 weeks

https://doi.org/10.1016/j.cmet.2020.06.008

28306

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons

E2

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons

Dlx

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons

E2

FP

1E12 vg/animal

RO

1 week

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons

E2

Chemogenetic PSAM4-5HT3-LC

1E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons, upper cortex layers

E11

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons, upper cortex layers

E14

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons cortex

E22

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, parvalbumin neurons global

E29

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Rat, Sprague-Dawley

CNS, parvalbumin neurons

E2

FP

Intracranial (cortex)

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

NHP, rhesus macaque

CNS, parvalbumin neurons

E2

FP

Intracranial (cortex)

https://doi.org/10.1038/s41593-020-0692-9

PHP.eB

POS

Mouse, PV-Cre

CNS, parvalbumin neurons

Brainbow

FP

2E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1038/s41467-020-18422-8

PHP.eB

POS

Human Organoid

F49B7 Retinal organoid

EF1a

Sensor, GCaMP6s

1.3E11 vg/organoid

Direct application to tissue

3-4 weeks

https://doi.org/10.1016/j.cell.2020.08.013

PHP.eB

POS

Mouse, C57BL/6J

CNS, brainstem serotonergic neurons

TPH2

Opsin, ChRmine, FP

4E11 vg/animal

RO

6 weeks

https://doi.org/10.1038/s41587-020-0679-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, purkinje neuron

L7

Opsin, ChRmine, FP

4E11 vg/animal

RO

2 months

https://doi.org/10.1038/s41587-020-0679-9

PHP.eB

POS

Mouse, C57BL/6J

CNS, purkinje neuron

L7

Opsin, ChRmine, FP

Intracranial

2 weeks

https://doi.org/10.1038/s41587-020-0679-9

PHP.eB

POS

Mouse, CD1

CNS, neurons

hSyn1

FP

RO

https://doi.org/10.1038/s41586-020-2926-0

PHP.eB

POS

Mouse, CD1

CNS, astrocytes

GfaBC1D

FP

RO

https://doi.org/10.1038/s41586-020-2926-0

PHP.eB

POS

Mouse, Flex-tdTomato

CNS, astrocytes

GfaBC1D

CRISPR, Cas9

RO

3 weeks

https://doi.org/10.1038/s41586-020-2926-0

PHP.eB

POS

Mouse, Flex-tdTomato

CNS, astrocytes

GfaBC1D

CRISPR, sgRNA, Recombinase, Cre

RO

3 weeks

https://doi.org/10.1038/s41586-020-2926-0

PHP.eB

POS

Mouse, CD1

CNS, astrocytes

GfaBC1D

Chemogenetic, Split TurboID

RO

4 weeks

https://doi.org/10.1038/s41586-020-2926-0

PHP.eB

POS

Mouse, CD1

CNS, neurons

hSyn1

Chemogenetic, Split TurboID

RO

4 weeks

https://doi.org/10.1038/s41586-020-2926-0

PHP.eB

POS

Mouse, CD1

CNS, astrocyte

GfaBC1D

Chemogenetic, TurboID

RO

4 weeks

https://doi.org/10.1038/s41586-020-2926-0

PHP.eB

POS

Mouse, PV-Cre

CNS, all

CBh

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.jneumeth.2020.108914

PHP.eB

POS

Mouse, PV-Cre

CNS, all

Ef1a DIO

FP, cSNAIL

4E11 vg/animal

RO

3-5 weeks

https://doi.org/10.1523/JNEUROSCI.1634-20.2020

160141

PHP.eB

POS

Mouse, Pvalb-2A-Cre Ai14

CNS, all

Ef1a DIO

FP, cSNAIL

4E11 vg/animal

RO

3-5 weeks

https://doi.org/10.1523/JNEUROSCI.1634-20.2020

160141

PHP.eB

NEG

Mouse, C57BL/6J neonate

CNS, all

CB7

FP

1E10 vg/animal

ICV

30 days

https://doi.org/10.1016/j.omtm.2020.10.011

PHP.eB

NEG

Mouse, C57BL/6J

CNS, olfactory bulb

CB7

FP

1E11 vg/animal

Intranasal

30 days

https://doi.org/10.1016/j.omtm.2020.10.011

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CB7

FP

1E11 vg/animal

Tail vein

30 days

https://doi.org/10.1016/j.omtm.2020.10.011

PHP.eB

NEG

Mouse, B6C3

CNS, all

CB7

FP

1E11 vg/animal

Tail vein

30 days

https://doi.org/10.1016/j.omtm.2020.10.011

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CB7, self complementary

FP

1E11 vg/animal

Tail vein

30 days

https://doi.org/10.1016/j.omtm.2020.10.011

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG neurons

hSyn

Chemogenetic, hM4D(Gi)

5E11 vg/site

Knee, intraarticular

3-4 weeks

https://doi.org/10.1002/art.41314

50475

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG neurons

hSyn

Chemogenetic, hM3D(Gq)

5E11 vg/site

Knee, intraarticular

3-4 weeks

https://doi.org/10.1002/art.41314

50474

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG neurons

CAG

FP

3E11 vg/site

Knee, intraarticular

3-4 weeks

https://doi.org/10.1002/art.41314

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG neurons

CAG

FP

1E12 vg/site

Knee, intraarticular

3-4 weeks

https://doi.org/10.1002/art.41314

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG sensory neurons

U6

shRNA

5E9 - 5E10 vg/animal

Intrathecal, lumbar

12 weeks

https://doi.org/10.1126/science.aaz5875

85741

PHP.S

NEG

Mouse, Swiss-Webster

PNS, trigeminal neurons, superior cervical ganglia

CBh

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41467-020-17936-5

PHP.S

POS

Mouse, C57BL/6J

PNS, Enteric plexus

hSyn

Inducer, tTA2

2.5E9 - 1E11 vg/animal

RO

3 weeks

https://doi.org/10.1111/nmo.14014

99120

PHP.S

POS

Mouse, C57BL/6J

PNS, Enteric plexus

TRE

FP

1E12 vg/animal

RO

3 weeks

https://doi.org/10.1111/nmo.14014

99131, 99114, 99113

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBA

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1089/hum.2019.186

PHP.B

NEG

Mouse, BALBcJ

CNS, all

CBA

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1089/hum.2019.186

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBA

FP

5E10 vg/animal

ICV

https://doi.org/10.1089/hum.2019.186

PHP.B

NEG

Mouse, BALBcJ

CNS, all

CBA

FP

5E10 vg/animal

ICV

https://doi.org/10.1089/hum.2019.186

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CMV

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41551-019-0501-5

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CMV

CRISPR, split intein CBE

4E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1038/s41551-019-0501-5

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CBh

FP

2E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1038/s41551-019-0501-5

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, all

CBh

CRISPR, split intein CBE

4E10 vg/animal

ICV

3-4 weeks

https://doi.org/10.1038/s41551-019-0501-5

137176, 137175

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, all

CBh

FP

1E10 vg/animal

ICV

3-4 weeks

https://doi.org/10.1038/s41551-019-0501-5

PHP.B

POS

Mouse, Rhodopsin-Cre Ai9

Retina

CBh

CRISPR, split intein CBE

5E9 vg/site

subretinal

3-4 weeks

https://doi.org/10.1038/s41551-019-0501-5

137176, 137175

PHP.B

POS

Mouse, Rhodopsin-Cre Ai9

Retina

CBh

FP

5E9 vg/site

subretinal

3-4 weeks

https://doi.org/10.1038/s41551-019-0501-5

PHP.eB

POS

Mouse, Npc1I1061T (c.3182T > C) neonate

CNS, all

CBh

CRISPR, split intein CBE

3E12 vg/animal

RO

up to 100 days

https://doi.org/10.1038/s41551-019-0501-5

137176, 137175

PHP.B

POS

Mouse, B6/129S neonate

CNS, all

CMV

FP

2E11 vg/animal

temporal facial vein

2 weeks

https://doi.org/10.1016/j.omtm.2020.05.021

PHP.B

POS

Mouse, B6/129 S-Fdxrm1J Otop3m1J/GrsrJ neonate

CNS, all

CMV

Rescue

2E11 vg/animal

temporal facial vein

up to 4 months

https://doi.org/10.1016/j.omtm.2020.05.021

PHP.B

POS

Mouse, Hexb−/−

CNS, all

BiCBA

Rescue

1E12 vg/animal

Tail vein

up to 600 days

https://doi.org/10.1016/j.ymthe.2020.06.021

PHP.B

POS

Mouse, Hexb−/−

CNS, all

BiCBA

Rescue

3E11 vg/animal

Tail vein

up to 600 days

https://doi.org/10.1016/j.ymthe.2020.06.021

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CMV

FP

3E11 vg/animal

Tail vein

3 weeks

https://dx.doi.org/10.7150%2Fthno.46992

PHP.eB

NEG

Mouse, Apoe-/-

CNS, all

CMV

FP

3E11 vg/animal

Tail vein

3 weeks

https://dx.doi.org/10.7150%2Fthno.46992

PHP.eB

NEG

Mouse, Ldlr-/-

CNS, all

CMV

FP

3E11 vg/animal

Tail vein

3 weeks

https://dx.doi.org/10.7150%2Fthno.46992

PHP.eB

NEG

Mouse, BALB/cJ

CNS, all

CMV

FP

3E11 vg/animal

Tail vein

3 weeks

https://dx.doi.org/10.7150%2Fthno.46992

PHP.eB

POS

Mouse, C57xBALB Ldlr+/-

CNS, all

CMV

FP

3E11 vg/animal

Tail vein

3 weeks

https://dx.doi.org/10.7150%2Fthno.46992

PHP.eB

POS

Mouse, CAS9+/− fetus

CNS, excitatory neurons

CBh

FP

5E9 - 1E10 vg/animal

In utero injection

3 weeks

https://doi.org/10.1242/dev.195586

PHP.eB

POS

Mouse, CAS9+/− fetus

CNS, excitatory neurons

CBh

CRISPR, sgRNA, FP

5E9 - 1E10 vg/animal

In utero injection

3 weeks

https://doi.org/10.1242/dev.195586

91947

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, all

CBA

FP

2E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.B

POS

Mouse, C57BL/6J [B6J.129(Cg)-Igs2tm1.1(CAG-cas9*)Mmw/J

CNS, all

CBA

FP, CRISPR, sgRNA

2E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.B

POS

Mouse, C57BL/6J [B6J.129(Cg)-Igs2tm1.1(CAG-cas9*)Mmw/J

CNS, all

CBA

FP, CRISPR, sgRNA

2E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.eB

POS

Mouse, C57BL/6J [B6J.129(Cg)-Igs2tm1.1(CAG-cas9*)Mmw/J

CNS, all

CBA

FP, CRISPR, sgRNA

5E10 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.eB

POS

Mouse, C57BL/6J [B6J.129(Cg)-Igs2tm1.1(CAG-cas9*)Mmw/J

CNS, all

CBA

FP, CRISPR, sgRNA

2E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

2.5E11 vg/animal

Tail vein

4-6 weeks

https://doi.org/10.3389/fbioe.2021.679483

AAV5-PHP.B

NEG

Mouse, C57BL/6J

CNS, all

CAG

FP

2.5E11 vg/animal

Tail vein

4-6 weeks

https://doi.org/10.3389/fbioe.2021.679483

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

miRNA

1E11 vg/site

Intracranial (striatum)

4-6 weeks

https://doi.org/10.3389/fbioe.2021.679483

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CAG

miRNA

4E12 vg/animal

Tail vein

4-6 weeks

https://doi.org/10.3389/fbioe.2021.679483

PHP.B

POS

Mouse, Ube3am−/p+ neonate

CNS, neuron

hSyn

Rescue

1.6E11 vg/animal

ICV

10-14 weeks

https://doi.org/10.1172/jci.insight.144712

PHP.B

POS

Mouse, C57BL/6J

CNS, neuron

hSyn

Rescue

1.6E11 vg/animal

ICV

10-14 weeks

https://doi.org/10.1172/jci.insight.144712

PHP.B

POS

Mouse, 5XFAD

CNS, neurons

hSyn

Rescue

6.25E13 vg/kg

Tail vein

2 weeks - 12 months

https://doi.org/10.1007/s13311-021-01151-1

PHP.B

POS

Mouse, 5XFAD

CNS, neurons

hSyn

FP

6.25E13 vg/kg

Tail vein

2 weeks - 12 months

https://doi.org/10.1007/s13311-021-01151-1

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Rescue

6.25E13 vg/kg

Tail vein

1,3,6 months

https://doi.org/10.1007/s13311-021-01151-1

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

FP

6.25E13 vg/kg

Tail vein

1,3,6 months

https://doi.org/10.1007/s13311-021-01151-1

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Rescue

3.12E13 vg/kg

Tail vein

1,3,6 months

https://doi.org/10.1007/s13311-021-01151-1

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Rescue

1.25E14 vg/kg

Tail vein

1,3,6 months

https://doi.org/10.1007/s13311-021-01151-1

PHP.B

POS

Mouse, Grin1flox/flox

CNS, astrocytes

GfaBC1D

Sensor, GCaMP3

1.4E11 vg/animal

RO

3 weeks

DOI: 10.1126/sciadv.abk1378

PHP.B

POS

Mouse, C57BL/6J

CNS, astrocytes

GfaBC1D

Sensor, GCaMP3

1.4E11 vg/animal

RO

3 weeks

DOI: 10.1126/sciadv.abk1378

PHP.B

POS

Mouse, AppNL-G-F

CNS, all

CAG

Rescue

1E12 vg/animal

Tail vein

12 months

https://doi.org/10.15252/emmm.201809824

PHP.B

POS

Mouse, C57BL/6J neonate

Cochlea neurons

hSyn

Sensor, vf-Chrimson

8.7E9 vg/animal

scala tympani

https://doi.org/10.15252/emmm.202013391

PHP.eB

POS

Mouse, C57BL/6J neonate

Cochlea neurons

hSyn

Sensor, vf-Chrimson-ES/TS

1.1E10 vg/animal

scala tympani

https://doi.org/10.15252/emmm.202013391

PHP.B

POS

Mouse, VGAT)-tdTomato

CNS, neurons

CBh

FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neulet.2021.135956

PHP.eB

POS

Mouse, VGAT)-tdTomato

CNS, neurons

mCaMKII

FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neulet.2021.135956

PHP.eB

POS

Mouse, VGAT)-tdTomato

CNS, neurons

SynI-mCMV

FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neulet.2021.135956

PHP.eB

POS

Mouse, VGAT)-tdTomato

CNS, neurons

NSE

FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neulet.2021.135956

PHP.eB

POS

Mouse, VGAT)-tdTomato

CNS, neurons

CBh

FP

2E11 vg/animal

RO

2 weeks

https://doi.org/10.1016/j.neulet.2021.135956

PHP.eB

POS

Mouse, KO ARSA

CNS, all

CAG

Rescue

5E11 vg/animal

RO

3 months

https://doi.org/10.3389/fnmol.2021.677895

PHP.B

POS

Mouse, C57BL/6J

CNS, neuron

Syn1

FP

3E11 vg/animal

ICV

4 weeks

https://doi.org/10.1089/hum.2020.301

PHP.B

NHP, rhesus macaque

CNS, neuron

Syn1

FP

2-4E12 vg/kg

ICV

4-4.5 weeks

https://doi.org/10.1089/hum.2020.301

PHP.eB

Cat

CNS, all

CAG

FP

5E8 vg/site

Intracranial (cortex)

7 days

https://doi.org/10.1016/j.isci.2021.102685

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

5E8 vg/site

Intracranial (cortex)

https://doi.org/10.1016/j.isci.2021.102685

PHP.eB

NHP, rhesus macaque

CNS, all

CAG

FP

2E9 vg/site

Intracranial (cortex)

7 days

https://doi.org/10.1016/j.isci.2021.102685

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CMV

FP

4.8E9 vg/site

Intracranial (anterior cingulate, cortex, cerebellum)

30 days

https://doi.org/10.1038/s41434-021-00272-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

X on

FP

2E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41586-021-03770-2

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

X on

Rescue

2E12 vg/animal

RO

4 weeks

https://doi.org/10.1038/s41586-021-03770-2

PHP.eB

NHP, macaca nemestrina

CNS, parvalbumin neurons

3xSP10ins-eHGT_359h-minRho*

FP

5E10 vg/site

Intracranial (cortex)

64 days

https://dx.doi.org/10.3791/62546

163504

PHP.eB

NHP, macaca nemestrina

CNS, cortex L5 neuron

eHGT_453m-minBglobin

FP

5E10 vg/site

Intracranial (cortex)

113 days

https://dx.doi.org/10.3791/62546

164453

PHP.eB

POS

Mouse, C57BL/6J

CNS, astrocytes

GFAP

Sensor, iGlow

7E9 vg/site

Intracranial (hippocampus)

2 weeks

https://doi.org/10.1242/jcs.255455

PHP.eB

POS

Mouse, Scn2agt/gt

CNS, all

EF1a

Recombinase, FLPo, FP

2E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.celrep.2021.109495

PHP.eB

POS

Mouse, Scn2agt/gt

CNS, all

EF1a

FP

2E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1016/j.celrep.2021.109495

PHP.eB

POS

Mouse, Scn2agt/gt

CNS, all

EF1a

Recombinase, FLPo, FP

5E7 vg/site

Intracranial (striatum)

3 weeks

https://doi.org/10.1016/j.celrep.2021.109495

PHP.eB

POS

Mouse, Scn2agt/gt

CNS, all

EF1a

FP

5E7 vg/site

Intracranial (striatum)

3 weeks

https://doi.org/10.1016/j.celrep.2021.109495

PHP.eB

POS

Mouse, Cabp2–/– neonate

Cochlea

hCMV hBA

Rescue, FP

8E9 vg/site

scala tympani

5-8 weeks

https://doi.org/10.3389/fnmol.2021.689415

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

5E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.3389/fneur.2021.685802

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CAG

FP

5E11 vg/animal

Tail vein

4 weeks

https://doi.org/10.3389/fneur.2021.685802

PHP.eB

NEG

Mouse, C57BL/6J

CNS, all

CAG

FP

5E10 vg/animal

Tail vein

4 weeks

https://doi.org/10.3389/fneur.2021.685802

PHP.eB

NEG

Mouse, C57BL/6J

CNS, all

CAG

FP

5E9 vg/animal

Tail vein

4 weeks

https://doi.org/10.3389/fneur.2021.685802

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

CamKIIa

FP

5E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.3389/fneur.2021.685802

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn1

FP

5E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.3389/fneur.2021.685802

PHP.eB

NHP, macaca fascicularis

CNS, all

CBA

FP

9E9 vg/site

Intracranial (putamen)

28 - 30 days

https://doi.org/10.1016/j.ymthe.2021.07.010

PHP.eB

NHP, macaca fascicularis

CNS, all

CBA

FP

3.2E11 vg/animal

ICV

28 - 30 days

https://doi.org/10.1016/j.ymthe.2021.07.010

PHP.eB

NHP, macaca fascicularis

CNS, all

CBA

FP

3.2E11 vg/animal

ICM

28 - 30 days

https://doi.org/10.1016/j.ymthe.2021.07.010

PHP.eB

NHP, macaca fascicularis

CNS, all

CBA

FP

3.2E11 vg/animal

Intrathecal, lumbar

28 - 30 days

https://doi.org/10.1016/j.ymthe.2021.07.010

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1128/JVI.01164-21

AAV1-PHP.B

NEG

Mouse, C57BL/6J

CNS, all

CB7

FP

1E12 vg/animal

Tail vein

3 weeks

https://doi.org/10.1128/JVI.01164-21

PHP.B

POS

Mouse, Rosa26-Cas9 knockin

CNS, all

4x U6

CRISPR, sgRNA

6E9 vg/animal

RO

2 months

https://doi.org/10.1016/j.cmet.2021.06.013

PHP.eB

POS

Mouse, Ndufs4-/-

CNS, all

EF1a

Rescue

6E12 vg/animal

RO

up to 280 days

https://doi.org/10.1016/j.cmet.2021.06.013

PHP.eB

POS

Mouse, Ndufs4-/-

CNS, all

EF1a

FP

6E12 vg/animal

RO

up to 280 days

https://doi.org/10.1016/j.cmet.2021.06.013

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

Syn

Sensor, GCaMP6s

IV

https://doi.org/10.1038/s41467-021-26255-2

PHP.B

NEG

Mouse, TgCRND8

CNS, cortex, striatum, thalamus

smCBA

FP

1E11 vg/animal

Tail vein, focused ultrasound FUS

3 weeks

https://doi.org/10.1016/j.omtm.2021.10.001

PHP.B

Mouse, TgCRND8

CNS, cortex, striatum, thalamus

smCBA

FP

1E10 vg/animal

Tail vein, focused ultrasound FUS

3 weeks

https://doi.org/10.1016/j.omtm.2021.10.001

PHP.B

NEG

Mouse, BalbcJ

CNS, cortex, striatum

smCBA

FP

1E11 vg/animal

Tail vein, focused ultrasound FUS

3 weeks

https://doi.org/10.1016/j.omtm.2021.10.001

PHP.eB

NEG

Mouse, C57BL/6J

Ef1a DIO

FP, cSNAIL

4E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1523/JNEUROSCI.2534-20.2021

PHP.eB

POS

Mouse, Pvalb-Cre

CNS, parvalbumin neurons

Ef1a DIO

FP, cSNAIL

4E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1523/JNEUROSCI.2534-20.2021

PHP.eB

POS

Mouse, Sst-Cre

CNS, somatostatin neurons

Ef1a DIO

FP, cSNAIL

4E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1523/JNEUROSCI.2534-20.2021

PHP.eB

POS

Mouse, Drd1-Cre

CNS, dopaminergic neurons

Ef1a DIO

FP, cSNAIL

4E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1523/JNEUROSCI.2534-20.2021

PHP.eB

POS

Mouse, Adora2a-Cre

CNS, stiatopallidal neurons

Ef1a DIO

FP, cSNAIL

4E11 vg/animal

RO

3-4 weeks

https://doi.org/10.1523/JNEUROSCI.2534-20.2021

PHP.B

NHP, rhesus macaque

CNS, all

CAG

FP

1E12 vg/animal

Intrathecal, lumbar

2 months

https://doi.org/10.3389/fbioe.2021.762209

PHP.eB

NHP, rhesus macaque

CAG

FP

1E12 vg/animal

Intrathecal, lumbar

2 months

https://doi.org/10.3389/fbioe.2021.762209

PHPeB

POS

Mouse, UCP1-Cre

CNS, hypothalamus

FP

8E10 vg/animal

RO

4 weeks

https://doi.org/10.1016/j.molmet.2021.101405

PHP.eB

POS

Mouse, Oxtr 1×PA-iCre/+

CNS, Oxtr neurons

CBh FLEX

FP

2.5E11 vg/animal

RO

4 weeks

https://doi.org/10.1523/ENEURO.0423-21.2022

PHP.eB

POS

Mouse, C57BL/6J

CNS, spinal cord neurons

hSyn

Rescue, FP

3E11 vg/animal

Intrathecal, lumbar

12 weeks

https://doi.org/10.1186/s13024-021-00511-x

PHP.S

POS

Mouse, C57BL/6J

PNS, DRG neurons

hSyn

Rescue, FP

3E11 vg/animal

Intrathecal, lumbar

12 weeks

https://doi.org/10.1186/s13024-021-00511-x

PHP.eB

POS

Mouse, Sarm1 KO

CNS, spinal cord neurons

hSyn

Rescue, FP

3E11 vg/animal

Intrathecal, lumbar

12 weeks

https://doi.org/10.1186/s13024-021-00511-x

PHP.S

POS

Mouse, Sarm1 KO

PNS, DRG neurons

hSyn

Rescue, FP

3E11 vg/animal

Intrathecal, lumbar

12 weeks

https://doi.org/10.1186/s13024-021-00511-x

PHP.eB

POS

Mouse, fosGFP

CNS, S1 neurons

Sensor, RCaMP1.07

1E9 vg/site

Intracranial (cortex)

1 week

DOI: 10.1126/science.abl5981

PHP.eB

POS

Mouse, C57BL/6J

CNS, S1 neurons

Sensor, RCaMP1.07

1E9 vg/site

Intracranial (cortex)

1 week

DOI: 10.1126/science.abl5981

PHP.eB

POS

Mouse, Thy1-Cre

CNS, S1 neurons

hSyn DIO

FP, Rescue, Retrograde tracing

Intracranial (cortex)

3 weeks

https://doi.org/10.1186/s13041-022-00898-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, S1 neurons

hSyn

FP, Rescue, Retrograde tracing

Intracranial (cortex)

3 weeks

https://doi.org/10.1186/s13041-022-00898-8

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

FP, Rescue, Retrograde tracing

4E11 vg/animal

IV

3 weeks

https://doi.org/10.1186/s13041-022-00898-8

PHP.eB

POS

Mouse, VGAT-Cre

CNS, GABAergic neurons

hSyn DIO

FP, Rescue, Retrograde tracing

4E11 vg/animal

IV

3 weeks

https://doi.org/10.1186/s13041-022-00898-8

PHP.eB

POS

Mouse, VGAT-Cre

CNS, GABAergic neurons

hSyn

FP, Rescue, Retrograde tracing

4E11 vg/animal

IV

3 weeks

https://doi.org/10.1186/s13041-022-00898-8

PHP.eB

POS

Mouse, Z-Q175-KI

CNS, striatum astrocytes

GfaBS1D

FP, Rescue

1E9 vg/site

Intracranial (striatum)

3-5 weeks

https://doi.org/10.3389/fncel.2021.792652

PHP.eB

POS

Mouse, Z-Q175-KI

CNS, astrocytes

GfaBS1D

FP, Rescue

2-4E11 vg/animal

IV

https://doi.org/10.3389/fncel.2021.792652

PHP.eB

POS

Mouse, C57BL/6J

CNS, endothelial pericyte

CAG

FP

4E11 vg/animal

RO or tail vein

2 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, C57BL/6J

CNS, endothelial pericyte

CAG

FP, Rescue

4E11 vg/animal

RO or tail vein

2 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, endothelial pericyte

CAG

FP

4E10 vg/animal

RO or tail vein

3 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, endothelial pericyte

CAG

FP, Rescue

4E10 vg/animal

RO or tail vein

3 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, BAT-GAL

CNS, endothelial pericyte

CAG

FP

4E11 vg/animal

RO or tail vein

2 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, BAT-GAL

CNS, endothelial pericyte

CAG

FP, Rescue

4E11 vg/animal

RO or tail vein

2 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, BAT-GAL

CNS, endothelial pericyte

CAG

FP

4E10 vg/animal

RO or tail vein

3 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, BAT-GAL

CNS, endothelial pericyte

CAG

FP, Rescue

4E10 vg/animal

RO or tail vein

3 weeks

DOI: 10.1126/science.abm4459

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn DIO, fDIO

FP

1E10 vg/animal

RO

18 days

https://doi.org/10.1038/s42003-022-03096-3

55650

PHP.eB

POS

Mouse, Crabp1 KO

CNS, spinal cord, neuromuscular junction

hSyn

Rescue, FP

3 months

https://doi.org/10.1038/s41418-022-00959-4

PHP.eB

POS

Mouse, Crabp1 KO

CNS, spinal cord, neuromuscular junction

hSyn

FP

3 months

https://doi.org/10.1038/s41418-022-00959-4

PHP.eB

POS

Mouse, mc1Bth/+ neonate

Cochlea

CMV, U6

CRISPR, CasRx sgRNA

5E9 vg/site

Round window membrane

2 weeks

https://doi.org/10.1038/s41392-022-00893-4

PHP.eB

POS

Mouse, Tmc1+/+

Cochlea

CMV, U6

CRISPR, CasRx sgRNA

5E9 vg/site

Round window membrane

2 weeks

https://doi.org/10.1038/s41392-022-00893-4

PHP.eB

POS

Mouse, B6/C3H neonate

CNS, all

CMV, U6

Rescue sup-tRNA, FP

1E11 vg/animal

IV

10 weeks

https://doi.org/10.1038/s41586-022-04533-3

PHP.eB

POS

Mouse, B6/C3H neonate

CNS, all

CMV, U6

Rescue sup-tRNA, FP

2E11 vg/animal

IV

10 weeks

https://doi.org/10.1038/s41586-022-04533-3

PHP.eB

POS

Mouse, Fmr1-KO

CNS, all

CMV

Rescue

5E11 vg/animal

RO

4 or 8 weeks

https://doi.org/10.15252/emmm.202114649

PHP.eB

Mouse, C57BL/6J

Muscle

CMV

FP

1E12 vg/animal

Intramuscular

4 weeks

https://doi.org/10.1016/j.genrep.2021.101227

PHP.eB

POS

Mouse, Per2fl/fl

CNS, astrocytes

GFAP

Recombinase, iCre, FP

1E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41598-021-91770-7

PHP.eB

POS

Mouse, Per2fl/fl

CNS, astrocytes

CAG

FP

1E11 vg/animal

Tail vein

3 weeks

https://doi.org/10.1038/s41598-021-91770-7

PHP.eB

NEG

Mouse, Per2fl/fl

CNS, astrocytes

GFAP

Recombinase, iCre, FP

1E11 vg/animal

Intraperitoneal, IP

3 weeks

https://doi.org/10.1038/s41598-021-91770-7

PHP.eB

POS

Mouse, Per2fl/fl

CNS, astrocytes

GFAP

Recombinase, iCre, FP

1E11 vg/animal

Intraperitoneal, IP

2 months

https://doi.org/10.1038/s41598-021-91770-7

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

hSyn

Rescue, FP, Epitope

5E11 vg/animal

RO

3 weeks

DOI: 10.7554/eLife.65417

PHP.eB

POS

Mouse, C57BL/6J

CNS, excitatory neurons

CamKIIa

FP

1E11 vg/animal

IV

3 weeks

https://doi.org/10.1038/s41598-021-95930-7

PHP.eB

POS

Mouse, C57BL/6J

CNS, gabaergic interneuron

mDLX

FP

1E11 vg/animal

IV

3 weeks

https://doi.org/10.1038/s41598-021-95930-7

83900

PHP.eB

POS

Mouse, 3xTg-AD

CNS, all

CMV

FP

1E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.1016/j.bbr.2021.113673

PHP.eB

POS

Mouse, 3xTg-AD

CNS, all

CMV

FP, Rescue

1E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.1016/j.bbr.2021.113673

PHP.eB

POS

Mouse, C57BL/6JRcc neonates

CNS, hippocampus

U6, hSyn

shRNA, FP

1-2E9 vg/site

ICV

3 weeks

https://doi.org/10.1523/JNEUROSCI.0908-21.2022

PHP.eB

POS

Rat, Sprague-Dawley

CNS, all

CAG

FP

6E11 vg/animal

ICM

1 month

https://doi.org/10.1038/s41434-021-00244-y

37825

PHP.eB

NEG

Rat, Sprague-Dawley

CNS, all

CAG

FP

6E10 vg/animal

ICM

1 month

https://doi.org/10.1038/s41434-021-00244-y

37825

PHP.B

POS

Mouse, Mcoln1−/−

CNS, all

CMV

Rescue, FP

1E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.1093/hmg/ddab093

PHP.B

POS

Mouse, Mcoln1−/+

CNS, all

CMV

Rescue, FP

1E12 vg/animal

Tail vein

4 weeks

https://doi.org/10.1093/hmg/ddab093

PHP.eB

POS

Mouse, Mmut−/− neonate

CNS, neurons

CamKIIa

Rescue

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2021.04.005

PHP.eB

POS

Mouse, Mmut−/−

CNS, neurons

CBA

FP

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2021.04.005

PHP.eB

POS

Mouse, Mmut+/− neonate

CNS, neurons

CamKIIa

Rescue

1E11 vg/animal

RO

3 weeks

https://doi.org/10.1016/j.omtm.2021.04.005

PHP.S

POS

Mouse, C57BL/6J

PNS, trigeminal ganglia

CAG

FP

0.7 - 5E11 vg/animal

RO

3 weeks

https://doi.org/10.3389/fnins.2021.715954

PHP.S

POS

Mouse, PV-RTM

PNS, Lumbar DRG

hSyn

FP

1-2E11 vg/animal

Intrathecal, lumbar

2 weeks

https://doi.org/10.1016/j.ymthe.2021.04.023

PHP.S

POS

Mouse, PV-RTM

PNS, Lumbar DRG

hSyn

FP

1-2E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.1016/j.ymthe.2021.04.023

PHP.S

POS

Mouse, PV-Cre

PNS, Lumbar DRG

hSyn FLEX

Chemogenetic, hM3Dq, FP

1-2E11 vg/animal

Intrathecal, lumbar

8 weeks

https://doi.org/10.1016/j.ymthe.2021.04.023

PHP.S

NEG

Mouse, C57BL/6J

PNS, schwann cells

CAG

FP

9E10 vg/animal

Intrathecal

6 weeks

https://doi.org/10.1038/s41598-021-02694-1

PHP.S

NEG

Mouse, C57BL/6J

PNS, schwann cells

CAG

FP

1E12 vg/animal

Tail vein

6 weeks

https://doi.org/10.1038/s41598-021-02694-1

PHP.eB

POS

Mouse, C57BL/6J neonate

CNS, neurons

hSyn, U6

FP, shRNA

ICV

https://doi.org/10.1073/pnas.2001679118

PHP.eB

POS

Mouse, LSL-Cas9

CNS, neurons

hSyn, U6

CRISPR, sgRNA, Recombinase, Cre

5E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.1016/j.omtm.2021.02.012

PHP.eB

POS

Mouse, LSL-Cas9

CNS, astrocytes

GFAP, U6

CRISPR, sgRNA, Recombinase, Cre

5E11 vg/animal

Tail vein

2 weeks

https://doi.org/10.1016/j.omtm.2021.02.012

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

FP

4E11 vg/animal

Tail vein

4 weeks

https://doi.org/10.1016/j.omtm.2020.12.006

PHP.eB

POS

Mouse, Vglut2-Cre

CNS, amygdala

hSyn

FP

1.2E11 vg/animal

RO

3 weeks

https://doi.org/10.1038/s41586-021-03413-6

PHP.eB

POS

Mouse, neonate

CNS, all

CMV

Rescue, FP

2E11 vg/animal

Intracardiac

https://doi.org/10.1007/s10565-021-09601-4

PHP.B

POS

Mouse, C57BL/6J

Cochlea

hSyn

Opsin, vf-Chrimson

1E10 vg/site

Round window membrane

https://doi.org/10.15252/emmm.202013391

PHP.eB

POS

Mouse, C57BL/6J

Cochlea

hSyn

Opsin, vf-Chrimson-ES/TS

1E10 vg/site

Round window membrane

https://doi.org/10.15252/emmm.202013391

PHP.eB

POS

Mouse, KO ARSA

CNS, all

CAG

Rescue

5E11 vg/animal

RO

3 months

https://doi.org/10.3389/fnmol.2021.677895

PHP.eB

POS

Mouse, SstCre/+ neonate

CNS, somatostatin neurons

hSyn DIO

Chemogenetic, hM4D(Gi), FP

2E10 vg/animal

ICV

9 weeks

https://doi.org/10.1093/ijnp/pyab002

44362

PHP.eB

POS

Mouse, SstCre/+ neonate

CNS, somatostatin neurons

hSyn DIO

FP

2E10 vg/animal

ICV

9 weeks

https://doi.org/10.1093/ijnp/pyab002

50459

PHP.eB

POS

Mouse, C57BL/6J

CNS, all

CMV

FP

3E9 vg/site

Intracranial (cortex, cerebellum)

https://doi.org/10.1038/s41434-021-00272-8

165441, 165442, 165443

PHP.S

POS

Mouse, Cck-Ires-Cre

PNS, myenteric neurons

CAG DIO

FP

5.7E11 vg/animal

Tail vein

2-3 weeks

https://doi.org/10.1038/s41593-020-00736-x

PHP.B

POS

Mouse, H11-Cas9 neonate

CNS, all

CAG U6

FP, CRISPR, sgRNA

1E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00224-2

PHP.B

POS

Mouse, H11-Cas9 neonate

CNS, all

CAG U6

FP, CRISPR, sgRNA

2E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00224-2

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

mGAD65

FP

5E12 vg/animal

RO

3 weeks

https://doi.org/10.1186/s13041-021-00746-1

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

mDlx

FP

5E12 vg/animal

RO

3 weeks

https://doi.org/10.1186/s13041-021-00746-1

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

mGAD65

FP

1E11 vg/site

Intrcranial (cerebellum)

https://doi.org/10.1186/s13041-021-00746-1

PHP.B

POS

Mouse, C57BL/6J

CNS, neurons

mDlx

FP

1E11 vg/site

Intrcranial (cerebellum)

https://doi.org/10.1186/s13041-021-00746-1

PHP.eB

POS

Mouse, C57BL/6J

CNS, neurons

mGAD65

FP

3E12 vg/animal

RO

3 weeks

https://doi.org/10.1186/s13041-021-00746-1

PHP.B

POS

Mouse, H11-Cas9 neonate

CNS, all

CBA U6

FP, CRISPR, sgRNA

5E10 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.eB

POS

Mouse, H11-Cas9 neonate

CNS, all

CBA U6

FP, CRISPR, sgRNA

5E10 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.B

POS

Mouse, H11-Cas9 neonate

CNS, all

CBA U6

FP, CRISPR, sgRNA

2E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.eB

POS

Mouse, H11-Cas9 neonate

CNS, all

CBA U6

FP, CRISPR, sgRNA

2E11 vg/animal

ICV

5-6 weeks

https://doi.org/10.1038/s41434-021-00223-3

PHP.B

POS

Mouse, C57BL/6J

CNS, all

CBh

miRNA

1E12 vg/animal

RO

3-4 weeks

https://doi.org/10.1016/j.neuroscience.2020.04.004