CLOVER center AAV engineering paper highlighted on the cover of Nature Neuroscience and in News and Views
In this paper we describe several vector tools for studying the central and peripheral nervous systems, including two capsids AAV-PHP.eB and AAV-PHP.S and a collection of AAV genomes.
Global representations of goal-directed behavior in distinct cell types of mouse neocortex"Allen, W.E., Kauvar, I.V., Chen, M.Z., Richman, E.B., Yang, S.J., Chan, K., Gradinaru, V., Deverman, B.E., Luo, L., Deisseroth, K. Neuron, 2017;94, 891-907. [Article]
Hillier, D., Fiscella, M., Drinnenberg, A., Trenholm, S., Rompani, S. B., Raics, Z., et al. (n.d.). Causal evidence for retina-dependent and -independent visual motion computations in mouse cortex. Nature Neuroscience, advance online publication SP - EP . [Article]
Bone CLARITY: Clearing, imaging, and computational analysis of osteoprogenitors within intact bone marrow" Greenbaum, A.*, Chan, K.Y.*, Dobreva, T., Brown, D., Balani, D.H., Boyce, R., Kronenberg, H.M., McBride, H.J., Gradinaru, V. Sci Transl Med, 2017; 9, eaah6518. [ Article | Caltech News Release | Nature Research Highlights | Popular Science]
Ken now joins the CLOVER Center as a postdoctoral fellow applying AAV-PHP vectors to the study and potential treatment of Huntington's disease.